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More than 15 percent of our genes are mobilized to defend against microbial attacks

The body's overwhelming genetic defense, which has implications for the survival of patients who are severely burned or injured, was revealed in a sweeping analysis of gene activity in volunteers who were injected with a bacterial product that temporarily created flu-like symptoms.

1 Sep 2005

When it comes to inflammation, too much of a good thing can be deadly

In some severely injured patients, this normal healing process can develop into a lethal, whole-body response, including bloodstream infection (sepsis) and multiple organ failure. How and why inflammation turns from healing to harming is still mysterious, so doctors can't accurately predict how each injured patient will fare.

31 Aug 2005

First human trials start in Canada for muscle-derived stem cells as a treatment for urinary incontinence

Human muscle-derived cells, pluripotent stem cells found in muscle, have been used to cure stress urinary incontinence in animal models, a finding which signals that these cells are prime candidates to treat the condition in adults.

31 Aug 2005

Vagus nerve stimulation (VNS) therapy for treatment-resistant depression proves effective for some patients

Vagus nerve stimulation (VNS) therapy, a treatment recently approved by the Food and Drug Administration for treatment-resistant depression, produced a positive response in more than 25 percent of patients in a national, yearlong study led by UT Southwestern Medical Center psychiatrists

31 Aug 2005

When it comes to heart bypass surgery, women twice as likely to die

According to a new study when it comes to heart bypass surgery, women are nearly twice as likely as men to die from complications.

30 Aug 2005

Episiotomies still common despite global recommendations to restrict use

Episiotomy is often called the unkindest cut of all. The procedure involves cutting the skin and muscles of the perineal area, the tissue between a woman's vagina and anus, while she is giving birth. It was once thought to be less painful and damaging than allowing the tissue to tear naturally.

30 Aug 2005

Outcomes of perineal laceration repair following childbirth

Women who have third-or fourth-degree perineal laceration repairs following the birth of their first baby have considerably different outcomes that can adversely impact quality of life and have implications on subsequent deliveries, according to Virginia Commonwealth University researchers.

30 Aug 2005

Aspirin shown to be beneficial before heart surgery

Surgeons who have been advising their patients to avoid taking aspirin in the days before surgery because they feared it could cause bleeding, will be reassured by the results of a new study.

30 Aug 2005

Good old fashioned soap and water the answer for "superbug"

Superbugs are bacteria that have mutated to become resistant to common antibiotics which are no longer any use against them.

30 Aug 2005

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

Many children who undergo bone marrow transplantation (BMT) as part of cancer treatment already have dental abnormalities that leave them vulnerable to potentially life-threatening bacterial infections, according to investigators at St. Jude Children's Research Hospital. A report on this study appears in the prepublication online edition of Bone Marrow Transplantation.

29 Aug 2005

Plastic surgery patients come from all walks of life

In the first-ever research of its kind, a study conducted by the American Society of Plastic Surgeons (ASPS) details the people considering plastic surgery and their motivations, debunking many stereotypes.

29 Aug 2005

Ellen MacKenzie to lead health policy and management department

Ellen J. MacKenzie, PhD, a leading expert in the study of injury prevention and trauma services research, has been selected to chair the Department of Health Policy and Management at the Johns Hopkins Bloomberg School of Public Health. MacKenzie, a professor in the Department and director of the Bloomberg School's Center for Injury Research and Policy , will begin her new duties on September 1, 2005.

29 Aug 2005

Minimally invasive prostate removal aided by a robot has possible benefits, high cost

Although minimally invasive prostate removal aided by a robot can lead to less blood loss, shorter hospital stays and fewer complications, there is no evidence that the procedure improves cure rates, according to a new technology assessment.

29 Aug 2005

Ways to avoid hazards of heart bypass under study

The heart-lung bypass machine that stills the heart while surgeons bypass an adult’s clogged arteries or repair a baby’s malformed heart can also trigger a potentially deadly inflammatory response.

28 Aug 2005

Elevated blood lactate levels may indicate poor prognosis in liver failure

A new study on fulminant hepatic failure (FHF), a sudden and severe shutdown of the liver, examined ways of determining early on whether patients would benefit from a transplant as opposed to responding to other medical treatment. The results showed that elevated blood lactate levels indicate a poor prognosis and thus the need for a transplant.

28 Aug 2005

Inflammation plays an important role in post-operative stroke

Duke University Medical Center researchers have discovered that patients who have two specific gene variants are more than three times as likely to suffer a stroke after heart surgery.

26 Aug 2005

No show patients cost the health service millions each year

According to a new survey, missed appointments costs the National Health Service in the UK £21m.

25 Aug 2005

Drug Cytotec as good as surgery at expelling tissue following failed pregnancy

According to test results just released, the drug Cytotec is almost as effective as surgery for removing tissue that can remain in the uterus after a failed pregnancy.

25 Aug 2005

Stem cells with heart bypass surgery trial to begin

The University of Pittsburgh Medical Center (UPMC) has been granted approval by the U.S. Food and Drug Administration (FDA) to conduct a clinical trial to determine the safety and feasibility of injecting a patient's own bone marrow-derived stem cells directly into the heart during conventional heart bypass surgery.

25 Aug 2005

Coronary angioplasty increases risk of developing Alzheimer's disease

Boston University School of Medicine (BUSM) researchers have discovered that patients who have either coronary artery bypass graft surgery or coronary angioplasty are at an increased risk of developing Alzheimer's disease.

25 Aug 2005