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Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Physicians are prescribing more opioid painkillers than ever before to patients undergoing common surgeries, according to new research from the department of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania.

21 Mar 2016

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Inc. today announced Valeant Pharmaceuticals International, Inc. will commercialize Mysimba (naltrexone HCl / bupropion HCl prolonged release) in Central and Eastern Europe.

15 Mar 2016

Research findings could help treat people with sexual disorders

Undesirable associations with sex can be unlearned, but return if the circumstances change. They must therefore be unlearned in different situations. The drug D-cycloserine may help here. These are the findings of psychologist Mirte Brom.

11 Mar 2016

Effective ways to ensure a long, healthy life

More people may be living to 100 and beyond than ever before, but the real challenge is how to become one of them yourself, and how to care for an aging population.

11 Mar 2016

Gar genome helps identify genetic sequences shared by human disease genes and zebrafish

Led by Drs John Postlethwait and Ingo Braasch from the Institute of Neuroscience, University of Oregon, US, in collaboration with the Broad Institute, the study of the Spotted Gar (Lepisosteus oculatus) genome reveals that it is small and manageable. Furthermore, it lacks much shuffling and duplication that occurred in the 'main' fish ancestral line; it conserved its genome.

10 Mar 2016

IUPUI researcher awarded $1.1 million grant to develop tools to improve care for chronic pain patients

An Indiana University-Purdue University Indianapolis researcher has been awarded $1.1 million to develop information-based tools to help primary care providers improve care for patients with chronic pain, a condition that affects 100 million Americans at a cost of $630 billion annually in health care costs and lost worker productivity.

10 Mar 2016

Overprescribing of opioids leads to serious public health problems

Overprescribing of opioids and opioid addiction are serious and growing public health problems in the U.S., and are the focus of a new report by an expert panel, entitled The American Opioid Epidemic: Population Health Implications and Potential Solutions," from the National Stakeholder Panel, Jefferson College of Population Health, which is published in a special supplement to Population Health Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The supplement is available open access on the Population Health Managementwebsite

10 Mar 2016

Early childhood intervention guide can help prevent substance use disorders

An online guide about interventions in early childhood that can help prevent drug use and other unhealthy behaviors was launched today by the National Institute on Drug Abuse, part of the National Institutes of Health.

10 Mar 2016

Scientists discover brain mechanisms that separate food consumption from cravings

Researchers investigating eating disorders often study chemical and neurological functions in the brain to discover clues to overeating. Understanding non-homeostatic eating -- or eating that is driven more by palatability, habit and food cues -- and how it works in the brain may help neuroscientists determine how to control cravings, maintain healthier weights and promote healthier lifestyles. Scientists at the University of Missouri recently discovered the chemical circuits and mechanisms in the brain that separate food consumption from cravings. Knowing more about these mechanisms could help researchers develop drugs that reduce overeating.

9 Mar 2016

Inhibition of mitochondrial calcium uptake specifically toxic to cancer cells

Inhibiting the transfer of calcium ions into the cell's powerhouse is specifically toxic to cancer cells, according to an article published this week in Cell Reports by researchers from the Perelman School of Medicine at the University of Pennsylvania.

4 Mar 2016

Researchers find key brain receptor linked to depression, drug addiction and Alzheimer's disease

Researchers at the University of Colorado Anschutz Medical Campus have found that a key receptor in the brain, once thought to only strengthen synapses, can also weaken them, offering new insights into the mechanisms driving depression, drug addiction and even Alzheimer's disease.

3 Mar 2016

Mobile device addiction linked to anxiety, depression in college-age students

Is cellphone use detrimental to mental health? A new study from the University of Illinois finds that addiction to, and not simply use of, mobile technology is linked to anxiety and depression in college-age students.

3 Mar 2016

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

The Centre for Addiction and Mental Health and Impel NeuroPharma have signed a licensing agreement to advance a new neuropeptide-based therapeutic approach shown to be effective in treating depression.

1 Mar 2016

Promising therapeutic strategy for relieving neuropathic pain

A specific molecule involved in maintaining pain after a nerve injury has been identified and blocked in mice by Hiroshima University researchers. These results reveal a promising therapeutic strategy for treating neuropathic pain.

1 Mar 2016

Scientists develop new optical technique to observe neurotransmitter activity of individual synapses

Columbia University scientists have developed a new optical technique to study how information is transmitted in the brains of mice. Using this method, they found that only a small portion of synapses -- the connections between cells that control brain activity--may be active at any given time.

26 Feb 2016

Increasing medication adherence: an interview with Dr Alejandro (Alex) Jaimes

Adherence applies to multiple levels of healthcare. Before a drug goes on the market it has to undergo testing in clinical trials: participants take the study drug and report how well the drug works, along with any side effects.

22 Feb 2016

People diagnosed with depression find difficult to stop smoking

People diagnosed with depression are about twice as likely to smoke as the general population. A survey of 6811 participants from Australia, Canada, the United Kingdom, and the USA, published today in the scientific journal Addiction, found that although depressed smokers tried to quit smoking more often than other smokers, they were more likely to return to smoking within a month.

22 Feb 2016

TSRI's Courtney Miller to receive Presidential Early Career Award for Scientists and Engineers

Courtney Miller, associate professor on the Florida campus of The Scripps Research Institute, has been selected to receive a Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the United States government on young professionals at the outset of their independent research careers.

19 Feb 2016

FDA-approved Alzheimer's medications may help people quit smoking

Despite several safe drug therapies available to help smokers quit, three-quarters report relapsing within six months of a quit attempt. University of Pennsylvania researchers Rebecca Ashare and Heath Schmidt saw potential for a permanent cessation solution in a class of FDA-approved medications used to improve cognitive impairments from Alzheimer's disease.

19 Feb 2016

Blue Cross Blue Shield Association commits to address nation's growing opioid crisis

Blue Cross Blue Shield Association and top executives from Blue Cross and Blue Shield companies around the country today committed to addressing the nation's growing opioid crisis with an executive-level committee that will investigate its impact on individuals, local communities and the healthcare system as a whole.

18 Feb 2016

Addiction News and Research

Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Research findings could help treat people with sexual disorders

Effective ways to ensure a long, healthy life

Gar genome helps identify genetic sequences shared by human disease genes and zebrafish

IUPUI researcher awarded $1.1 million grant to develop tools to improve care for chronic pain patients

Overprescribing of opioids leads to serious public health problems

Early childhood intervention guide can help prevent substance use disorders

Scientists discover brain mechanisms that separate food consumption from cravings

Inhibition of mitochondrial calcium uptake specifically toxic to cancer cells

Researchers find key brain receptor linked to depression, drug addiction and Alzheimer's disease

Mobile device addiction linked to anxiety, depression in college-age students

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

Promising therapeutic strategy for relieving neuropathic pain

Scientists develop new optical technique to observe neurotransmitter activity of individual synapses

Increasing medication adherence: an interview with Dr Alejandro (Alex) Jaimes

People diagnosed with depression find difficult to stop smoking

TSRI's Courtney Miller to receive Presidential Early Career Award for Scientists and Engineers

FDA-approved Alzheimer's medications may help people quit smoking

Blue Cross Blue Shield Association commits to address nation's growing opioid crisis

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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