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MITHRAS trial investigates superiority of TMVR-induced iASD over medical therapy

The MITHRAS randomized clinical trial found that interventional closure of an iatrogenic atrial septal defect (iASD) driven by transcatheter mitral valve repair (TMVR) was not superior to conservative medical treatment with regard to the primary endpoint of change in six-minute walking distance.

16 Oct 2020

REFLECT II clinical trial evaluates safety and efficacy of cerebral embolic deflection filter

The REFLECT II randomized clinical trial evaluating the safety and efficacy of a device designed to reduce cerebral embolization and ischemic stroke, complications of transcatheter aortic valve replacement (TAVR), found that the device met the primary safety endpoint compared to historical controls but did not demonstrate superiority of the device for the primary hierarchical efficacy endpoint.

16 Oct 2020

Study challenges current standard for managing blood pressure in people with spinal cord injury

New research from the International Collaboration on Repair Discoveries (ICORD) challenges the current standard for managing blood pressure in people with spinal cord injury (SCI).

16 Oct 2020

NFID issues new report detailing risks of co-infection with flu and COVID-19 in vulnerable adults

The National Foundation for Infectious Diseases (NFID) issued a new Call to Action report detailing the risks of co-infection with influenza (flu) and COVID-19 in adults with chronic health conditions, and the importance of flu vaccination during the 2020-2021 season.

16 Oct 2020

New self-expanding bioprosthetic valve used in TAVR fails to demonstrate non-inferiority

In a randomized clinical trial, SCOPE II, a new self-expanding bioprosthetic valve used in transcatheter aortic valve replacement (TAVR) failed to demonstrate non-inferiority compared to an existing self-expanding valve.

16 Oct 2020

Synthetic signals could help control tissue regeneration, guide cellular therapies

For a tiny embryo to develop into an adult organism, its cells must develop in precise patterns and interact with their neighbors in carefully orchestrated ways.

16 Oct 2020

Study: E-cigarettes may not be a safer alternative to smoking during pregnancy

E-cigarettes might not be a safer alternative to smoking during pregnancy, according to the first known study into the effects of prenatal nicotine exposure on babies.

16 Oct 2020

A strategic collaboration to speed up the development of allogeneic cell therapies

The University of Texas MD Anderson Cancer Center and Allogene Therapeutics, Inc. today announced a strategic five-year collaboration agreement for the preclinical and clinical investigation of AlloCAR T candidates across Allogene's broad portfolio of hematologic and solid tumors.

16 Oct 2020

Tech Spotlight honors ISSCR's stem cell based clinical trials guide

The ISSCR's Stem Cell-Based Clinical Trials: Practical Advice for Physicians and Ethics/Institutional Review Committees was honored today by Tech Spotlight at Harvard Kennedy School's Belfer Center.

16 Oct 2020

UofSC scientists identify biological triggers that promote quicker nerve regeneration

University of South Carolina scientists are exploring ways to make nerve regeneration happen faster and more successfully.

15 Oct 2020

Glutathione precursor improves multiple deficits associated with premature aging

Premature aging in people with HIV is now recognized as a new, significant public health challenge. Accumulating evidence shows that people with HIV who are between 45 to 60 years old develop characteristics typically observed in people without HIV that are more than 70 years of age.

15 Oct 2020

Early trauma leads to changes in blood metabolites, study finds

A study by the Brain Research Institute at UZH reveals that early trauma leads to changes in blood metabolites - similarly in mice and humans.

15 Oct 2020

UTHSC professor receives $2.2 million for research into arterial stiffness and hypertension

In humans, large arteries lose elasticity and thicken with age and other pathological conditions, leading to arteriosclerosis and high blood pressure.

15 Oct 2020

Researchers develop a biodegradable, fast-acting thermotherapy patch from plant leaves

A team of researchers at Tampere University, Finland, has developed a biodegradable, transparent, flexible and fast-acting thermotherapy patch from plant leaves. The patch is compatible with flexible electronic applications. Plant material was used to reduce the amount of electronic waste.

15 Oct 2020

Bariatric surgery associated with longer life expectancy

People who have undergone obesity (bariatric) surgery live three years longer, on average, than those given conventional treatment for their obesity, a University of Gothenburg study shows. Compared with the general population, however, both groups' excess mortality is high.

15 Oct 2020

Cocaine use in mice leads to the formation of synapses by astrocytes

Drugs of abuse, like cocaine, are so addictive due in part to their cellular interaction, creating strong cellular memories in the brain that promote compulsive behaviors.

15 Oct 2020

Moffitt study uncovers how specific molecules promote cancer progression

The development of cancer is a highly complicated process, involving multiple genes and signaling pathways that become upregulated or downregulated throughout different stages of tumor growth and spread.

15 Oct 2020

Joint project receives NIH funding to assess the benefits of AI-enabled toilet seat technology

Toilet seats with high-tech sensors might be the non-invasive technology of the future that could help reduce hospital return rates of individuals with heart disease.

15 Oct 2020

New technology precisely diagnoses sickle cell disease in a minute

Researchers at the University of Colorado Boulder and the University of Colorado Anschutz Medical Campus have developed a new way to diagnose diseases of the blood like sickle cell disease with sensitivity and precision and in only one minute.

15 Oct 2020

Scientists engineer powerful novel anti-microbial molecules from wasp venom

Now, a team of scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered potent novel anti-microbial molecules from toxic proteins found in wasp venom. The researchers believe that the discovery holds promise in fighting the increasing number of antibiotic-resistant bacteria, that cause serious illness.

15 Oct 2020

Medicine News and Research

MITHRAS trial investigates superiority of TMVR-induced iASD over medical therapy

REFLECT II clinical trial evaluates safety and efficacy of cerebral embolic deflection filter

Study challenges current standard for managing blood pressure in people with spinal cord injury

NFID issues new report detailing risks of co-infection with flu and COVID-19 in vulnerable adults

New self-expanding bioprosthetic valve used in TAVR fails to demonstrate non-inferiority

Synthetic signals could help control tissue regeneration, guide cellular therapies

Study: E-cigarettes may not be a safer alternative to smoking during pregnancy

A strategic collaboration to speed up the development of allogeneic cell therapies

Tech Spotlight honors ISSCR's stem cell based clinical trials guide

UofSC scientists identify biological triggers that promote quicker nerve regeneration

Glutathione precursor improves multiple deficits associated with premature aging

Early trauma leads to changes in blood metabolites, study finds

UTHSC professor receives $2.2 million for research into arterial stiffness and hypertension

Researchers develop a biodegradable, fast-acting thermotherapy patch from plant leaves

Bariatric surgery associated with longer life expectancy

Cocaine use in mice leads to the formation of synapses by astrocytes

Moffitt study uncovers how specific molecules promote cancer progression

Joint project receives NIH funding to assess the benefits of AI-enabled toilet seat technology

New technology precisely diagnoses sickle cell disease in a minute

Scientists engineer powerful novel anti-microbial molecules from wasp venom

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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