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CPhA supports Medi-Cal lawsuit against the California Department of Health Care Services

The California Pharmacists Association (CPhA) today announced its support for a lawsuit filed December 3, 2013 in San Francisco Superior Court against the California Department of Health Care Services (DHCS) over the Medi-Cal provider reimbursement cuts.

11 Dec 2013

Navidea receives Fast Track designation for Lymphoseek injection

Navidea Biopharmaceuticals, Inc. (NYSE MKT:NAVB), a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, announced today that the US Food and Drug Administration (FDA) has granted Fast Track designation to Lymphoseek® (technetium 99m tilmanocept) Injection for sentinel lymph node detection in patients with head and neck cancer.

11 Dec 2013

Baxter seeks FDA approval of OBI-1 for adults with acquired hemophilia A

Baxter International Inc. today announced that the company has submitted a biologics license application (BLA) to the U.S. Food and Drug Administration (FDA) for the approval of OBI-1, a recombinant antihemophilic porcine sequence factor VIII, in patients with acquired hemophilia A.

From Baxter International Inc. 11 Dec 2013

Avanir Pharmaceuticals' AVP-923 phase II trial fails to meet primary efficacy endpoint

Avanir Pharmaceuticals, Inc. today announced that PRIME, its phase II clinical trial of the investigational drug AVP-923 (dextromethorphan / quinidine) for the treatment of central neuropathic pain in patients with multiple sclerosis did not meet the primary efficacy endpoint.

10 Dec 2013

Biosimulation and epilepsy treatments: an interview with Dr. Serge Bischoff, CEO of Rhenovia and RHENEPI program director

The need for biosimulation is primarily to do with the very high attrition rate in drug development and especially in the development of drugs for the central nervous system.

10 Dec 2013

Sanofi US launches second PiPH innovation challenge to improve drug development process

Today, Sanofi US launched its second Partners in Patient Health Innovation Challenge: Collaborate | Innovate, which will award $100,000 to the winning team. This year's theme is "Co-Creating for Breakthroughs: Moving toward a collaborative research and development ecosystem."

10 Dec 2013

Computational predictive toxicology services available in SafeBridge Consultants

SafeBridge Consultants, Inc., a division of Trinity Consultants, Inc., Dallas, TX, with offices in Mountain View, CA, New York, NY, and Liverpool, UK, announces the availability of computational predictive toxicology services to the biopharmaceutical and chemical industry.

10 Dec 2013

Preparing for better management of Tamiflu-resistant influenza viruses

Researchers in Umeå and Uppsala have found that residues of the influenza drug Tamiflu in our environment can make the influenza virus in birds resistant. This can have serious consequences in the event of an influenza pandemic. With more than 14 million SEK from the Swedish Research Councils Formas and VR, the research team will now continue their studies with a focus on alternative antiviral drugs.

10 Dec 2013

Epilepsy experts discuss on new NTI definition, bioequivalence guidelines at AES annual meeting

For several years, epilepsy practitioners have questioned the U.S. Food and Drug Administration's definition of bioequivalence as it applies to narrow therapeutic index drugs, such as those used for epilepsy. In response to these concerns, the FDA has sponsored 3 studies of antiepileptic drugs and also convened an advisory board to help determine which drugs are NTI.

10 Dec 2013

Studies expose high prevalence of epilepsy and other neurological disorders in US Veterans

Three studies coming out of the American Epilepsy Society's 67th Annual Meeting in Washington DC expose the high prevalence of epilepsy and other neurological disorders in US Veterans who served in Operation Enduring Freedom, Operation Iraqi Freedom and Operation New Dawn. The research conducted from these studies indicate that veterans are at a particularly high risk for traumatic brain injury, post traumatic stress disorder, psychological non-epileptic seizures and epileptic seizure diagnoses.

10 Dec 2013

Researchers develop new drug-eluting contact lens for prolonged delivery of glaucoma medication

For nearly half a century, contact lenses have been proposed as a means of ocular drug delivery that may someday replace eye drops, but achieving controlled drug release has been a significant challenge.

10 Dec 2013

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue. The findings are the latest from the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and appear in the December 9 edition of the scientific journal Cancer Cell.

10 Dec 2013

Children hospitalized for pneumonia have similar outcomes with big gun antibiotics or penicillin

Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with "big gun" antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin, according to a Vanderbilt study published in Pediatrics.

10 Dec 2013

Acetylon announces positive preclinical data of ricolinostat (ACY-1215) in models of lymphoma

Acetylon Pharmaceuticals, Inc., the leader in the development of selective histone deacetylase (HDAC) inhibitors for enhanced therapeutic outcomes, announced that positive preclinical data of selective HDAC6 inhibitor, ricolinostat (ACY-1215), in models of lymphoma were presented today in an oral presentation by Dr. Jennifer Amengual, Assistant Professor of Medicine & Experimental Therapeutics, Columbia University Medical Center.

10 Dec 2013

New drug that blocks defective gene can arrest Waldenstrom's Macroglobulinemia in animal models

In nearly one-third of patients with Waldenstrom's Macroglobulinemia, a specific genetic mutation switches on the disease, and a new drug that blocks the defective gene can arrest the disease in animal models, researchers at Dana-Farber Cancer Institute and allied institutions will report at the 2013 annual meeting of the American Society of Hematology.

10 Dec 2013

European study investigates high blood pressure drug for treating Alzheimer's patients

An extensive European study is currently investigating whether a drug used to treat high blood pressure may also help patients with Alzheimer's disease. The EU is investing almost 6 million euros on the project, in which Sahlgrenska Academy and Sahlgrenska University Hospital are responsible for Sweden's contribution.

10 Dec 2013

Study demonstrates feasibility to detect generalized tonic-clonic seizures with arm device

Medications remain the mainstay of epilepsy treatment, and to date there are no FDA-approved devices that provide an accurate means of detection for generalized tonic-clonic seizures, or convulsions, during activities of daily living. Two new studies presented at the American Epilepsy Society's 67th Annual Meeting in Washington D.C. provide data that warrants the development of non-invasive devices with the capability to signal the onset of an epileptic seizure and could be crucial to optimal patient dosing.

10 Dec 2013

New findings on effects of epilepsy on mother and child

New research pertaining to the latest findings on the effects of epilepsy on both the mother and child were presented at the American Epilepsy Society's 67th Annual Meeting in Washington DC. These studies explore folic acid use, the effect of surgery with intractable focal epilepsy, and antiepileptic drug exposure during breastfeeding.

10 Dec 2013

IBN and IBM discover new medical application for converted PET bottles

Researchers at Singapore's Institute of Bioengineering and Nanotechnology (IBN) and California's IBM Research - Almaden (IBM) have discovered a new, potentially life-saving application for polyethylene terephthalate (PET), which is widely used to make plastic bottles.

10 Dec 2013

Drugmaker pushes new drug over cheaper equivalent at Medicare's expense

The Washington Post explores the public impact of doctors' decisions to choose a more expensive drug to prevent blindness despite trials showing the drug is equivalent to a much cheaper product.

9 Dec 2013

Drugs News and Research

CPhA supports Medi-Cal lawsuit against the California Department of Health Care Services

Navidea receives Fast Track designation for Lymphoseek injection

Baxter seeks FDA approval of OBI-1 for adults with acquired hemophilia A

Avanir Pharmaceuticals' AVP-923 phase II trial fails to meet primary efficacy endpoint

Biosimulation and epilepsy treatments: an interview with Dr. Serge Bischoff, CEO of Rhenovia and RHENEPI program director

Sanofi US launches second PiPH innovation challenge to improve drug development process

Computational predictive toxicology services available in SafeBridge Consultants

Preparing for better management of Tamiflu-resistant influenza viruses

Epilepsy experts discuss on new NTI definition, bioequivalence guidelines at AES annual meeting

Studies expose high prevalence of epilepsy and other neurological disorders in US Veterans

Researchers develop new drug-eluting contact lens for prolonged delivery of glaucoma medication

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Children hospitalized for pneumonia have similar outcomes with big gun antibiotics or penicillin

Acetylon announces positive preclinical data of ricolinostat (ACY-1215) in models of lymphoma

New drug that blocks defective gene can arrest Waldenstrom's Macroglobulinemia in animal models

European study investigates high blood pressure drug for treating Alzheimer's patients

Study demonstrates feasibility to detect generalized tonic-clonic seizures with arm device

New findings on effects of epilepsy on mother and child

IBN and IBM discover new medical application for converted PET bottles

Drugmaker pushes new drug over cheaper equivalent at Medicare's expense

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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