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Phasefocus™ appoints Chinese distributor as part of Asia expansion

Phasefocus continues to increase its global international profile with the appointment of Nuohai Life Sciences as the company’s exclusive distributor for mainland China, Hong Kong and Macau.

From Phase Focus Limited 11 Dec 2017

Breakthrough research could lead to development of yeast-based protein therapies

It took several years, but a research team headed by Professor Jens Nielsen at Chalmers University of Technology has finally succeeded in mapping out the complex metabolism of yeast cells.

11 Dec 2017

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

New genetic model identified for predicting outcomes in patients with primary myelofibrosis

A group of investigators from Mayo Clinic and multiple academic research centers in Italy have identified a genetic model for predicting outcomes in patients with primary myelofibrosis who are 70 years or younger and candidates for stem cell transplant to treat their disease.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Novel compound along with checkpoint inhibitors may enhance immune response in melanoma patients

A novel compound may restore immune response in patients with melanoma, according to a study presented at the ESMO Immuno Oncology Congress 2017.

8 Dec 2017

Simple molecular test may help predict presence of high-grade pancreatic cancers

A report in The Journal of Molecular Diagnostics, describes a new simple molecular test to detect chromosomal abnormalities -- biomarkers known as telomere fusions--in pancreatic tumor specimens and pancreatic cyst fluids.

8 Dec 2017

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

Researchers have discovered a mechanism of resistance to checkpoint inhibitors and how to reverse it. The biomarker results from the IMvigor210 study are reported at the ESMO Immuno Oncology Congress 2017.

8 Dec 2017

Researchers develop molecular beacon to find hypoxic spots in real time

Areas of hypoxia, or low oxygen in tissue, are hallmarks of fast-growing cancers and of blockages or narrowing in blood vessels, such as stroke or peripheral artery disease. University of Illinois researchers have developed a way to find hypoxic spots noninvasively in real time.

8 Dec 2017

MIT researchers discover new way to make bacteria vulnerable to existing antibiotics

MIT researchers have discovered a way to make bacteria more vulnerable to a class of antibiotics known as quinolones, which include ciprofloxacin and are often used to treat infections such as Escherichia coli and Staphylococcus aureus.

8 Dec 2017

Taurine could boost effectiveness of existing multiple sclerosis therapies

New research suggests that administering taurine, a molecule naturally produced by human cells, could boost the effectiveness of current multiple sclerosis (MS) therapies.

8 Dec 2017

Researchers seek to understand role of novel protein in tumor metastasis

Metastasis, the process in which a tumor spreads to other parts of the body, is responsible for 90% of deaths from tumors. It is the greatest challenge to a cancer patient's survival. Metastatic spread occurs in several steps, these include that tumor cells become mobile and cross into and out of blood vessels.

8 Dec 2017

3D mini brains put researchers on a fast track to repair the nervous system

The Houston Methodist Research Institute is making mini brains from human stem cells that put researchers on a fast track to repair the nervous system after injury or disease of the brain and spinal cord.

8 Dec 2017

IUPUI researchers receive $1.8 million grant to develop potential treatments for hydrocephalus

No drug treatment exists for hydrocephalus, the buildup of fluid known as "water on the brain" that can occur at any age.

8 Dec 2017

Research brings scientists one step closer to understanding development of ALS

University of Michigan-led research brings scientists one step closer to understanding the development of neurodegenerative disorders such as ALS.

8 Dec 2017

Optogenetics research sheds new light on social-spatial learning

Ilana Witten didn't set out to study spatial learning. She thought she was investigating how mice socialize--but she discovered that in mouse brains, the social and the spatial are inextricably linked.

8 Dec 2017

Using digital devices before bed may contribute to sleep and nutrition problems in children

It may be tempting to let your kids stay up late playing games on their smartphones, but using digital devices before bed may contribute to sleep and nutrition problems in children, according to Penn State College of Medicine researchers.

8 Dec 2017

Study identifies mechanism that could explain early link between sound input and cognitive function

Some expectant parents play classical music for their unborn babies, hoping to boost their children's cognitive capacity. While some research supports a link between prenatal sound exposure and improved brain function, scientists had not identified any structures responsible for this link in the developing brain.

7 Dec 2017

B Cell News and Research

Phasefocus™ appoints Chinese distributor as part of Asia expansion

Breakthrough research could lead to development of yeast-based protein therapies

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

New genetic model identified for predicting outcomes in patients with primary myelofibrosis

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Two immunotherapy approaches for multiple myeloma show hope

Novel compound along with checkpoint inhibitors may enhance immune response in melanoma patients

Simple molecular test may help predict presence of high-grade pancreatic cancers

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

Researchers develop molecular beacon to find hypoxic spots in real time

MIT researchers discover new way to make bacteria vulnerable to existing antibiotics

Taurine could boost effectiveness of existing multiple sclerosis therapies

Researchers seek to understand role of novel protein in tumor metastasis

3D mini brains put researchers on a fast track to repair the nervous system

IUPUI researchers receive $1.8 million grant to develop potential treatments for hydrocephalus

Research brings scientists one step closer to understanding development of ALS

Optogenetics research sheds new light on social-spatial learning

Using digital devices before bed may contribute to sleep and nutrition problems in children

Study identifies mechanism that could explain early link between sound input and cognitive function

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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