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Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer. However, the particles have to be injected into patients, which has limited their usefulness so far.

27 Nov 2013

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine. Dopamine is the neurotransmitter that sends messages to the part of the brain that controls movement and coordination.

27 Nov 2013

Supreme Court to hear arguments on health law's contraceptive coverage mandate

The justices accepted a pair of cases that raise questions not just about religious freedom and equality for female employees, but whether the religious beliefs of the owners of secular corporations allows them to not comply with a law.

27 Nov 2013

Findings highlight possible new approach to combat malaria

An international team of scientists, including researchers at Columbia University Medical Center, has identified a key metabolic enzyme that common malaria parasites require for survival at each stage of infection in humans. The findings raise the possibility of a new approach to combating malaria, one of the world's deadliest diseases. The study was published today in the online edition of the journal Nature.

27 Nov 2013

Call for greater beta blocker use in COPD

Researchers say that stubbornly low rates of beta-blocker prescribing in patients with chronic obstructive pulmonary disease could be contributing toward increased mortality in these patients following myocardial infarction.

27 Nov 2013

US may be losing ground as the leader in biomedical research

The United States may be losing ground as the leader in biomedical research and within the next five years will be second to China in the funds it spends for R&D, according to Francis Collins, M.D., Ph.D, director of the National Institutes of Health.

27 Nov 2013

First Edition: Nov. 27, 2013

Kaiser Health News staff writer Phil Galewitz, in collaboration with McClatchy, reports: "Like half the states, South Carolina chose not to expand Medicaid under the federal health law next year, citing the program's high costs and inefficiency. Yet, state officials still forecast a 16 percent enrollment jump by the end of June, 2015, triple that of a typical year and even higher than the 12 percent average increase expected in states that are expanding eligibility.

27 Nov 2013

European research project examines toxicity factor to fight AIDS

December 1st is the annual World AIDS Day, a perfect opportunity to look at how medical research is progressing to fight the disease.

27 Nov 2013

Genetics and cardiovascular drugs: an interview with Nancy Lurker, CEO of PDI and Paul Kinnon, CEO of Transgenomic, Inc.

People inherit different versions of any particular gene, and some genes affect how patients process and metabolize medicines. This especially holds true for people with cardiovascular (CV) disease. They may be fast, slow or non-metabolizers and might also react badly (with serious adverse events) to certain drug therapies or not at all.

27 Nov 2013

FDA grants Orphan Drug Designation to CMC Contrast's CMC-001 MRI contrast media

CMC Contrast AB, a privately owned drug development company that is developing a targeted contrast agent for Magnetic Resonance Imaging (MRI), announced today that Orphan Drug Designation has been granted by the US Food and Drug Administration (FDA) for its liver specific contrast agent CMC-001.

27 Nov 2013

Alpha Biolaboratories launches first accredited next day DNA paternity testing service in UK

A Warrington-based DNA testing laboratory is offering the UK's first standard next day paternity results service and is on a recruitment drive to cope with the anticipated increase in demand.

27 Nov 2013

WHO releases new treatment guidelines for children suffering severe acute malnutrition

WHO today released new treatment guidelines for the almost 20 million children under-five worldwide who have severe acute malnutrition.

27 Nov 2013

Drug interactions impact use of cholesterol-lowering statin drugs

A new study has found that many people who stopped taking cholesterol-lowering statin drugs were also taking an average of three other drugs that interfered with the normal metabolism of the statins.

27 Nov 2013

Researchers show how unusual properties of A3G protein help fight HIV infection

A collaborative team led by a Northeastern University professor may have altered the way we look at drug development for HIV by uncovering some unusual properties of a human protein called APOBEC3G.

27 Nov 2013

Protecting or boosting neurotrophins may slow progression of Huntington's disease

A drug that acts like a growth-promoting protein in the brain reduces degeneration and motor deficits associated with Huntington's disease in two mouse models of the disorder, according to a study appearing November 27 in the Journal of Neuroscience. The findings add to a growing body of evidence that protecting or boosting neurotrophins - the molecules that support the survival and function of nerve cells - may slow the progression of Huntington's disease and other neurodegenerative disorders.

27 Nov 2013

Isis Pharmaceuticals commences Phase 1 study of ISIS-GSK3Rx for treatment of common viral infection

Isis Pharmaceuticals, Inc. announced today that it has initiated a Phase 1 study for ISIS-GSK3Rx and earned a $3 million milestone payment from GlaxoSmithKline.

27 Nov 2013

Breakthrough discovery could lead to development of future therapeutics for prostate cancer

Drs. Andrew Goldstein, Owen Witte, and Tanya Stoyanova and their colleagues from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have found that prostate cancer can develop in one type of stem cell, then evolve to be maintained by a stem cell that looks very different, making prostate cancer stem cells a "moving target" for treatments. The breakthrough discovery connects directly to the development of future therapeutics that target cancer and was published online ahead of print in the Proceedings of the National Academy of Sciences.

27 Nov 2013

Merck announces approval of NOXAFIL delayed-release tablets by FDA

Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved NOXAFIL® (posaconazole) 100 mg delayed-release tablets.

27 Nov 2013

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

A team of researchers at Cold Spring Harbor Laboratory (CSHL) has identified a leukemia-specific stretch of DNA called an enhancer element that enables cancerous blood cells to proliferate in Acute Myeloid Leukemia (AML), a devastating cancer that is incurable in 70% of patients.

27 Nov 2013

San Diego School of Medicine receives grant to provide professional training to senior drivers

For the seventh consecutive year, the Training, Research and Education for Driving Safety (TREDS) program at the University of California, San Diego School of Medicine has been awarded a grant from the California Office of Traffic Safety (OTS) that will help keep our roadways and senior drivers safe through professional training.

27 Nov 2013

Drugs News and Research

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

Supreme Court to hear arguments on health law's contraceptive coverage mandate

Findings highlight possible new approach to combat malaria

Call for greater beta blocker use in COPD

US may be losing ground as the leader in biomedical research

First Edition: Nov. 27, 2013

European research project examines toxicity factor to fight AIDS

Genetics and cardiovascular drugs: an interview with Nancy Lurker, CEO of PDI and Paul Kinnon, CEO of Transgenomic, Inc.

FDA grants Orphan Drug Designation to CMC Contrast's CMC-001 MRI contrast media

Alpha Biolaboratories launches first accredited next day DNA paternity testing service in UK

WHO releases new treatment guidelines for children suffering severe acute malnutrition

Drug interactions impact use of cholesterol-lowering statin drugs

Researchers show how unusual properties of A3G protein help fight HIV infection

Protecting or boosting neurotrophins may slow progression of Huntington's disease

Isis Pharmaceuticals commences Phase 1 study of ISIS-GSK3Rx for treatment of common viral infection

Breakthrough discovery could lead to development of future therapeutics for prostate cancer

Merck announces approval of NOXAFIL delayed-release tablets by FDA

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

San Diego School of Medicine receives grant to provide professional training to senior drivers

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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