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Unraveling the complexity of cancer biology can prompt new avenues for drug development

Unraveling the complexity of cancer biology can lead to the identification of new molecules involved in breast cancer and prompt new avenues for drug development. And proteogenomics, an integrated, multipronged approach, seems to be a way to do it.

13 Dec 2018

Virginia Tech and UC San Diego researchers team up to develop nonopioid drug for chronic pain

Researchers from the Virginia Tech School of Neuroscience are teaming with the University of California San Diego and the U.S. National Institutes of Health to develop a drug -- now in its earliest stages -- that can treat certain types of chronic pain without the addictive consequences of opioids.

12 Dec 2018

Researchers use INTEGRA's VIAFLO 96/384 to streamline the experimental workflow

Researchers are using INTEGRA’s VIAFLO 96/384 multichannel electronic pipette to study Pseudomonas aeruginosa.

From INTEGRA Biosciences 12 Dec 2018

New collaborative partnership in quest of novel antibiotics

The Global Antibiotic Research and Development Partnership, Eisai Co., Ltd. and Takeda Pharmaceutical Company Limited have signed an agreement for GARDP to access and screen components of Eisai and Takeda's chemical libraries.

12 Dec 2018

Study discovers link between meditation and how individuals respond to feedback

In a new study in the Journal of Cognitive, Affective & Behavioral Neuroscience researchers from the University of Surrey have discovered a link between meditation and how individuals respond to feedback.

11 Dec 2018

Natural flavonoid is effective at treating leishmanisis infections, study shows

Current treatment options for the parasitic disease leishmaniasis are largely ineffective, expensive, and tend to be plagued by resistant parasites and side effects. Now, researchers reporting in PLOS Neglected Tropical Diseases have showed that a natural flavonoid is effective at treating Leishmania amazonensis infections.

11 Dec 2018

Caffeine plus another compound in coffee may fight Parkinson’s disease

Rutgers scientists have found a compound in coffee that may team up with caffeine to fight Parkinson's disease and Lewy body dementia - two progressive and currently incurable diseases associated with brain degeneration.

10 Dec 2018

MIT researchers develop antimicrobial peptides from South American wasp’s venom

The venom of insects such as wasps and bees is full of compounds that can kill bacteria. Unfortunately, many of these compounds are also toxic for humans, making it impossible to use them as antibiotic drugs.

7 Dec 2018

Cannabis-based compound shows promise to reduce seizures in children with epilepsy

Interest has been growing in the use of cannabinoids--the active chemicals in cannabis or marijuana-- for the treatment of epilepsy in children. A recent Epilepsia analysis of relevant published studies indicates that this strategy looks promising.

5 Dec 2018

Study of infrequent cannabis users compares adverse effects of vaping and smoking

In a small study of infrequent cannabis users, Johns Hopkins Medicine researchers have shown that, compared with smoking cannabis, vaping it increased the rate of short-term anxiety, paranoia, memory loss and distraction when doses were the same.

4 Dec 2018

Major soil organic matter compound battles chronic wasting disease

A major compound in soil organic matter degrades chronic wasting disease prions and decreases infectivity in mice, according to a study published November 29 in the open-access journal PLOS Pathogens by Judd Aiken of the University of Alberta, and colleagues.

3 Dec 2018

Paleo diet linked to heart disease biomarker

More than twice the amount of a key biomarker linked closely to heart disease has been found in the blood of people on the paleo diet.

29 Nov 2018

Curry spice may improve exercise intolerance related to heart failure

New research suggests that curcumin, a main ingredient in curry, may improve exercise intolerance related to heart failure. The study is published ahead of print in the Journal of Applied Physiology.

29 Nov 2018

Gel formulation of a new male contraceptive on trial

The National Institutes of Health (NIH) is funding a clinical trial to see the safety and effectiveness of a new male contraceptive that would be available in gel formulation.

29 Nov 2018

Research reveals how a small molecule helps remove excess cholesterol

Scientists have determined the structure of the activated form of an enzyme that helps to return excess cholesterol to the liver, a study in eLife reports.

27 Nov 2018

Study finds genetic links between alcohol dependence and psychiatric disorders

In the largest study of genetic factors linked to alcohol dependence, an international team of researchers identified a gene known to affect risk, and they determined that many other genes also contribute to risk for alcohol dependence to a lesser degree.

26 Nov 2018

Researchers harness visible light to develop safer building block for drug discovery

When you reach for a bottle of acetaminophen, you may be looking for relief from a headache. But if you take more than what is recommended, the drug can damage your liver.

22 Nov 2018

Researchers characterize new animal model that mimics aspects of AMD

Age-related macular degeneration affects roughly 200,000 individuals in the United States each year. In most, it comes on slowly, gradually blurring the central field of vision used for activities like reading and driving. While treatments exist to slow its progression, there is no cure.

22 Nov 2018

New research project to combat obesity, type 2 diabetes receives NIH funding

A research project headed by a faculty member from the Ohio University Heritage College of Osteopathic Medicine, which will explore whether administering a protein that's produced in the body can help prevent obesity and type 2 diabetes, has received $464,145 in funding from the National Institutes of Health.

20 Nov 2018

Towards finding a druggable cancer target

It's known that cancer involves unchecked cell growth and that a biological pathway that regulates organ size, known at the Hippo pathway, is also involved in cancer.

19 Nov 2018