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Researchers find CFI deficiency alarmingly high in old order Amish

Researchers from Children's Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population.

13 Aug 2025

Study supports pre-surgery use of GLP-1 RAs for weight reduction

Overweight patients waiting for operations could safely use a particular type of weight-loss treatment to reduce the risk of surgical complications linked to their obesity, a new study reveals.

12 Aug 2025

Lifestyle interventions key to closing life expectancy gap in mental illness

Mental health services must urgently increase investment in lifestyle interventions to improve care and help close the 15-year life expectancy gap faced by people with mental illness, a new Lancet Psychiatry Commission report warns.

12 Aug 2025

Mount Sinai receives major grant for new initiative dedicated to reducing cancer care disparities

The American Cancer Society (ACS) has awarded The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai a $4.08 million grant to establish the Cancer Health Research Center at Mount Sinai, a new initiative dedicated to reducing cancer-related health inequities across New York City.

12 Aug 2025

New COPD diagnostic schema identifies additional individuals at risk of poor respiratory outcomes

The diagnosis of chronic obstructive pulmonary disease, or COPD, is improved by incorporating CT lung imaging and respiratory symptoms.

12 Aug 2025

Adding MET inhibitor enhances immune response against small cell lung tumors

Adding a MET gene inhibitor enhances the effect of combined chemotherapy and immunotherapy in small cell lung cancer (SCLC), according to a multicenter study led by the Hospital del Mar Research Institute, in collaboration with researchers from the CIBERONC cancer research network.

12 Aug 2025

New injectable skin graft mimics dermis and promotes healing

Researchers have created what could be called "skin in a syringe". The gel containing live cells can be 3D printed into a skin transplant, as shown in a study conducted on mice.

12 Aug 2025

Contact lens with OLED offers safer simpler retinal diagnosis

Electroretinography (ERG) is an ophthalmic diagnostic method used to determine whether the retina is functioning normally.

12 Aug 2025

3D-printed kidney tumors offer a new tool in the fight against renal cancer

Scientists at Tsinghua University have developed a method to grow kidney tumors in the lab using cells from real patients, offering a potential new tool in the fight against renal cancer.

12 Aug 2025

Experts say rural emergency rooms are increasingly run without doctors

There was no doctor on-site when a patient arrived in early June at the emergency room in the small hospital at the intersection of two dirt roads in this town of 400 residents.

12 Aug 2025

Lavender oil could speed recovery after brain surgery

Lavender essential oil aromatherapy improves sleep quality and reduces postoperative delirium in brain surgery patients, offering a natural aid for recovery.

12 Aug 2025

Study identifies risk factors that increase risk of death in children with Fontan circulatory failure

A multi-center study has identified critical risk factors that increase the likelihood of death in children with a heart defect who are awaiting or have recently undergone heart transplantation, according to findings published in Circulation.

11 Aug 2025

Breakthrough approaches enhance RNA delivery while minimizing inflammation

Lipid nanoparticles (LNPs) are tiny fat bubbles that are used to deliver medicines, genes, and RNA into cells. However, in some cases LNPs can cause harmful inflammation as a result of the process of RNA delivery.

11 Aug 2025

Brain cells follow rhythmic patterns during learning and memory retrieval

A research team from the University Hospital Bonn (UKB), the University of Bonn, and the Medical Center - University of Freiburg has gained new insights into the brain processes involved in encoding and retrieving new memory content.

11 Aug 2025

Fetal procedure dramatically reduces mortality in high-risk Vein of Galen Malformation cases

Building upon the success of the first in utero brain surgery for Vein of Galen Malformation (VOGM) reported in 2023, new data published today in JAMA provides further evidence for the potential use of fetal embolization for this condition.

11 Aug 2025

New subcutaneous EEG device offers breakthrough in epilepsy monitoring

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London in partnership with the Mayo Clinic and UNEEG medical, has found that an electronic device placed under the scalp is an effective and feasible means of accurately tracking epilepsy.

11 Aug 2025