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Breast cancer and MEN1: exploring the connection

Researchers evaluated the role of Multiple Endocrine Neoplasia 1 (MEN1) messenger ribonucleic acid (mRNA) in breast cancer

17 Jul 2023

Intensive exercise slows the course of Parkinson's disease, study finds

Neuroscientists from the Faculty of Medicine of the Catholic University, Rome Campus, and the A. Gemelli IRCCS Polyclinic Foundation found that intensive exercise could slow the course of Parkinson's disease and described the biological mechanisms.

14 Jul 2023

Combination therapy shows promise in treating advanced ER+ breast cancer

Advanced estrogen receptor-positive (ER+) breast cancer can be especially difficult to treat. A new study by researchers at Dartmouth Cancer Center led by Todd W. Miller, PhD, shows promise in using a combination of estrogen and a PARP inhibitor (a drug that suppresses DNA damage repair), to treat this type of cancer.

13 Jul 2023

Scientists discover mechanism of cell death in people living with HIV

Professor Simona Stäger's team has made a breakthrough in the study of the human immunodeficiency virus (HIV).

13 Jul 2023

Researchers find new way to target leprosy infection

Leprosy has existed since at least Biblical times, yet scientists still don't know exactly how Mycobacterium leprae causes the disease's symptoms.

12 Jul 2023

Cetuximab plus radiotherapy effective in treating locally advanced cutaneous squamous cell cancer

A new research paper was published in Oncotarget's Volume 14 on July 7, 2023, entitled, "Effectiveness and toxicity of cetuximab with concurrent RT in locally advanced cutaneous squamous cell skin cancer: a case series."

12 Jul 2023

How does SARS-CoV-2 affect the placenta during pregnancy?

Researchers examine host responses to SARS-CoV-2 within the placenta using transcriptomics.

12 Jul 2023

Difficult transmembrane protein targets for therapeutic antibodies

In this interview, News-Medical talks to Sylvia Xie, product scientist at Sino Biological, about the ongoing emergence of transmembrane proteins as targets for therapeutic antibodies.

From Sino Biological Inc. 12 Jul 2023

New insights into how dendritic cells arm T cells to fight disease

As part of the immune system, dendritic cells are essential for fighting body cells that have degenerated or are infected with a virus.

11 Jul 2023

Orexin is crucial to the regulation of pupil size, research shows

The way the brain regulates pupil size is different from previously thought: fundamentally responsible is the neurotransmitter orexin, as researchers at ETH Zurich have now shown.

11 Jul 2023

The genetics of neurogenic inflammation in rosacea

Researchers identify rare genetic variants in families with rosacea.

11 Jul 2023

Scientists investigate a bat virus with pandemic potential

The devastating COVID-19 pandemic occurred when the SARS-CoV-2 virus, native to a species of bats, mutated to infect humans.

10 Jul 2023

New research sheds light on role of progesterone in breast cancer

A new research perspective was published in Oncotarget's Volume 14 on July 1, 2023, entitled, "Deciphering the mechanisms of action of progesterone in breast cancer."

10 Jul 2023

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Researchers investigated the role of senescent cells in the context of SARS-CoV-2 infection.

10 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

How B-cells and androgens contribute to the development of PCOS

Researchers evaluate the role of B-cell frequencies in the pathogenesis of polycystic ovary syndrome.

9 Jul 2023

Case report and review of a novel chromosomal abnormality in AML patient

A new research paper was published in Genes & Cancer on June 28, 2023, entitled, "A novel t (5; 17) (q35; q21) associated with t (8; 21) (q22; q22) in a patient with acute myeloid leukemia: case report and review of literature."

7 Jul 2023

Cryo-EM helps decode the molecular architecture of a neural transport protein

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter.

6 Jul 2023

NOSTER & Science Microbiome Prize winner illuminates how "silent flagellins" from commensal microbiota evade innate immunity

Sara Clasen is the 2023 winner of the NOSTER & Science Microbiome Prize for her work in illuminating how "silent flagellins" from commensal microbiota evade a host's innate immunity.

6 Jul 2023

Study provides insights into the molecular mechanism of Batten disease

Neuronal Ceroid Lipofuscinosis are a group of devastating neurodegenerative lysosomal storage disorders that begin in childhood. Mutations in CLN3 gene lead to a NCL called Batten disease, characterized by the progressive loss of vision, movement, and cognition.

6 Jul 2023