Heart News and Research

RSS

Experimental drugs from Sanofi and Regenron cut cholesterol in a new way

An experimental drug that acts in a novel way to lower cholesterol proved even more effective than statins and had few undesirable side effects, newly released data shows. The drug acts by modifying the way cholesterol levels are naturally controlled. A protein produced in the liver helps limit the amount of LDL, or “bad” cholesterol, that liver cells can remove from the bloodstream. The new drug, called REGN727, is a monoclonal antibody, made in a laboratory, that blocks the action of that protein.

27 Mar 2012

Chocolate for weight loss: Study

The US survey of a population of more than 1000 adults, published as a research letter in the Archives on Internal Medicine, reinforces the idea that chocolate packs heart healthy benefits, despite its high calorie and sugar content. For the study the participants reported eating chocolate an average of twice a week and exercising an average of 3.6 times a week. Their average age was 57.

27 Mar 2012

New CMS requirement increases ICD placement costs

The cost to place an implantable cardioverter-defibrillator (ICD) increased by $844 per case after a new requirement from the Centers for Medicare and Medicaid Services (CMS) went into effect in February 2010, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

First Edition: March 27, 2012

In today's headlines, the Supreme Court chronicles continue, with reports detailing what happened during yesterday's opening-day oral arguments and previewing what's on tap for today.

27 Mar 2012

Study reveals clinically relevant differences between on pump and off pump bypass

A large randomized trial comparing bypass surgery done with a heart-lung machine (on pump) and without it (off pump) found no differences in results between techniques overall but some clinically relevant differences, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

High-risk, high-cost PCI patients can be identified through pre-procedure bleeding risk score

A pre-procedure bleeding risk score can accurately identify high-risk, high-cost patients and may provide an opportunity to employ bleeding avoidance strategies to improve patient outcomes and reduce total costs related to percutaneous coronary intervention (PCI) procedures, according to a retrospective study being presented March 26 at the 61st annual American College of Cardiology (ACC) scientific session.

27 Mar 2012

Improved clinical quality leads to decline in quality of patients' experiences

Hospitals that adopt strategies to reduce errors and meet government requirements face an initial tradeoff between improved clinical quality and a decline in the quality of individual patients' experiences, according to new research.

27 Mar 2012

Detailed CT scan can safely and quickly rule out possibility of heart attack

A highly detailed CT scan of the heart can safely and quickly rule out the possibility of a heart attack among many patients who come to hospital emergency rooms with chest pain, according to the results of a study that will be presented by researchers from the Perelman School of Medicine at the University of Pennsylvania today at the American College of Cardiology's 61st Annual Scientific Session and published concurrently in the New England Journal of Medicine.

27 Mar 2012

Study shows safe and effective protocol for chest pain patients

Rhode Island Hospital physicians report that managing chest pain patients within an emergency department chest pain unit by both emergency medicine staff and cardiologists is safe and effective and may lower the use of stress testing.

27 Mar 2012

CRT-D appropriate for patients with left ventricular dysfunction

Cardiac resynchronization therapy with defibrillators (CRT-D) is appropriate for patients who have left ventricular dysfunction and require chronic ventricular pacing, based on the findings of an observational study that being presented March 26 that the 61st annual American College of Cardiology (ACC) scientific session.

27 Mar 2012

Catheter-based heart valve procedures effective for patients with aortic stenosis

Patients diagnosed with aortic stenosis who are too sick for open-heart surgery have better survival rates and an improved quality of life after undergoing catheter-based heart valve replacement than if the patients had been treated with standard medical therapy, according to a study authored by a Cedars-Sinai Heart Institute physician based on results from a multicenter clinical trial.

27 Mar 2012

Minimally invasive treatments re-establish blood flow in people with chronic DVT

Interventional radiology treatments re-establish blood flow in people with chronic deep vein thrombosis (DVT), reducing disabling symptoms and improving the quality of life for those afflicted with post-thrombotic syndrome—an under-recognized but frequent long-term complication of DVT.

27 Mar 2012

Pacemaker may effectively prevent NMS-related fainting spells

A select number of patients who suffer from neurally mediated synope (NMS) - a disorder in which the brain fails to regulate heart rate and blood pressure - may be good candidates to receive a dual-chamber pacemaker to prevent common NMS-related fainting spells, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

Bariatric surgery effectively controls diabetes

Overweight, diabetic patients who underwent bariatric surgery achieved significant improvement or remission of their diabetes, according to new research from Cleveland Clinic.

27 Mar 2012

UAB cardiac rehab program reduces mortality among people with heart attack

After two heart attacks and 10 stents, Rick Vinson had a decision to make — do nothing and likely die from heart disease like his father or take a chance at having a long life. Vinson chose the latter. After receiving his last stent in October 2010, he entered a cardiac rehab program at the University of Alabama at Birmingham. Since then he has dropped 20 pounds, his cholesterol has dropped to 141 from 315 and his triglycerides are down to 149 from 465.

27 Mar 2012

Scientists create first full 3-D images of vitamin B12

In a paper published recently in the journal Nature, scientists from the University of Michigan Health System and the Massachusetts Institute of Technology report they have created the first full 3-D images of B12 and its partner molecules twisting and contorting as part of a crucial reaction called methyltransfer.

27 Mar 2012

CCTA can safely and rapidly identify candidates for discharge from EDs

Coronary CT angiography (CCTA) -- a non-invasive way to look inside arteries that supply blood to the heart -- can quickly and reliably determine which patients complaining of chest pain at an emergency department can safely be sent home, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

Angioplasty can be safely and effectively performed at community hospitals

New evidence shows that with appropriate preparation, angioplasty can be safely and effectively performed at community hospitals without on-site cardiac surgery units, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

SAR236553/REGN727 antibody reduces LDL by up to 72% in patients

A novel monoclonal antibody identified in a new study dramatically lowered circulating LDL cholesterol by 40 percent to 72 percent, a development with potential to provide a new option for patients who are resistant to cholesterol-lowering drugs such as statins or to the current standard of care, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

27 Mar 2012

Researchers launch major aspirin trial to eradicate H. pylori

Researchers have launched a major clinical trial to investigate whether eliminating a common stomach bug could help to make taking aspirin safer in some patients.

27 Mar 2012