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UCSB study demonstrates new tool to resolve structure of membrane proteins

Membrane proteins are responsible for transporting chemicals and messages between a cell and its environment. But determining their structure has proved challenging for scientists. A study by UC Santa Barbara's Han Research Group demonstrates a new tool to resolve the structure of membrane-embedded and membrane-associating proteins using the water dynamics gradient they found across and above the lipid bilayer as a unique ruler.

1 Oct 2013

Sun Pharma, Intrexon partner to develop controllable gene-based therapies for ocular diseases

Sun Pharmaceutical Industries Ltd., an international specialty pharmaceutical company focused on chronic diseases, through its subsidiary, and Intrexon Corporation, a leader in synthetic biology, today announced the formation of a joint venture to develop controllable gene-based therapies for the treatment of ocular diseases that cause partial or total blindness in millions of people worldwide.

1 Oct 2013

Research reveals significant role of Axl receptor in progression, therapeutic resistance of AML

BerGenBio AS, an oncology biopharmaceutical company, announces that a paper entitled "Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine cross-talk of leukemia cells with bone marrow stroma" by Ben-Batalla et al., has been published in Blood, the most cited peer-reviewed research journal in the field of hematology.

1 Oct 2013

Standoff between a mutated gene and normal counterpart keeps certain cancer cells alive

What keeps leukemia cells alive almost forever, able to continue dividing endlessly and aggressively? New research at the Weizmann Institute suggests that, in around a quarter of all leukemias, the cancer cells rely on an internal "balance of terror" to keep going.

1 Oct 2013

Insulin interaction map could lead to new therapeutic targets for type 2 diabetes

A team led by scientists at The Scripps Research Institute has created the first comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete the hormone insulin. The finding makes possible a deeper scientific understanding of the insulin secretion process—and how it fails in insulin disorders such as type 2 diabetes.

1 Oct 2013

FDA grants accelerated approval to Perjeta for neoadjuvant treatment of breast cancer

The U.S. Food and Drug Administration today granted accelerated approval to Perjeta (pertuzumab) as part of a complete treatment regimen for patients with early stage breast cancer before surgery (neoadjuvant setting). Perjeta is the first FDA-approved drug for the neoadjuvant treatment of breast cancer.

1 Oct 2013

Researchers discover how aspirin improves survival in patients diagnosed with colon cancer

Researchers believe they have discovered how aspirin improves survival in patients diagnosed with colon cancer, the 2013 European Cancer Congress (ECC2013) heard today.

1 Oct 2013

Shortage of zinc may contribute to diseases like Alzheimer's and Parkinson's

Scientists at the University of Wisconsin-Madison have made a discovery that, if replicated in humans, suggests a shortage of zinc may contribute to diseases like Alzheimer's and Parkinson's, which have been linked to defective proteins clumping together in the brain.

1 Oct 2013

Researchers show that men experience more harm than good from routine PSA screening

Prostate cancer screening using the prostate-specific antigen (PSA) test is widely used in France despite a lack of evidence showing that it reduces cancer deaths. Now, researchers have shown that men experience more harm than good from routine PSA screening, according to research to be presented on Monday by Professor Mathieu Boniol, at the 2013 European Cancer Congress (ECC2013).

1 Oct 2013

Roadmap of protein interactions may lead to new therapeutic approaches for type 2 diabetes

A team led by scientists at The Scripps Research Institute (TSRI) has created the first comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete the hormone insulin.

1 Oct 2013

Virginia Tech faculty receives NIH New Innovator Award to research on influenza transmission

Influenza strikes five to 15 percent of the population and is estimated to cost the U.S. economy a hefty $90 million per year. If researchers can improve the understanding of how environmental conditions affect the ability of the influenza virus to survive and infect others while it is airborne, they may be able to help improve prediction and control of its spread.

1 Oct 2013

Vitamin D levels linked to emphysema

Researchers have found a relationship between emphysema and serum vitamin D levels, suggesting that the vitamin may play a role in modulating lung structure.

30 Sep 2013

Pfizer Licenses Gliknik's Pooled IVIG In $25M+ Deal

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30 Sep 2013

Researchers discover how aspirin improves survival in patients with colon cancer

Researchers believe they have discovered how aspirin improves survival in patients diagnosed with colon cancer, the 2013 European Cancer Congress heard today (Monday).

30 Sep 2013

Men with prostate cancer experience more harm than good from routine PSA screening

Prostate cancer screening using the prostate-specific antigen test is widely used in France despite a lack of evidence showing that it reduces cancer deaths. Now, researchers have shown that men experience more harm than good from routine PSA screening, according to research to be presented today (Monday) by Professor Mathieu Boniol, at the 2013 European Cancer Congress.

30 Sep 2013

Biology of tumour more important than primary site, say researchers

Identifying the molecular profile of a tumour where the primary site is unknown is crucial to the choice of treatment, the 2013 European Cancer Congress, will hear on Monday.

30 Sep 2013

Scientists discover two new compounds that could help treat CF patients having common mutation

Cystic fibrosis is a lethal genetic disorder that in France affects one child per 4,500 births. An international team led by scientists at the Institut Fédératif de Recherche Necker-Enfants Malades (CNRS/Inserm/Université Paris Descartes), led by Aleksander Edelman, has recently discovered two new compounds that could be used to treat patients carrying the most common mutation.

30 Sep 2013

Study suggests relationship between smoking history, response to inhibiting PD-L1/PD-1 pathway

New results from a trial of an antibody that helps the immune system to recognise and attack cancer cells have shown particularly encouraging responses in patients who are smokers or former smokers.

30 Sep 2013

First Phase II study: Everolimus drug slows spread of advanced papillary kidney cancer

The first Phase II study to investigate the use of the anti-cancer drug, everolimus, for the initial treatment of advanced papillary kidney cancer has shown that it is successful in slowing or preventing the spread of the disease, according to research to be presented today (Sunday) at the 2013 European Cancer Congress.

29 Sep 2013

Scientists unravel secrets of mechanism that snips our genes

Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.

27 Sep 2013

Protein C News and Research

UCSB study demonstrates new tool to resolve structure of membrane proteins

Sun Pharma, Intrexon partner to develop controllable gene-based therapies for ocular diseases

Research reveals significant role of Axl receptor in progression, therapeutic resistance of AML

Standoff between a mutated gene and normal counterpart keeps certain cancer cells alive

Insulin interaction map could lead to new therapeutic targets for type 2 diabetes

FDA grants accelerated approval to Perjeta for neoadjuvant treatment of breast cancer

Researchers discover how aspirin improves survival in patients diagnosed with colon cancer

Shortage of zinc may contribute to diseases like Alzheimer's and Parkinson's

Researchers show that men experience more harm than good from routine PSA screening

Roadmap of protein interactions may lead to new therapeutic approaches for type 2 diabetes

Virginia Tech faculty receives NIH New Innovator Award to research on influenza transmission

Vitamin D levels linked to emphysema

Pfizer Licenses Gliknik's Pooled IVIG In $25M+ Deal

Researchers discover how aspirin improves survival in patients with colon cancer

Men with prostate cancer experience more harm than good from routine PSA screening

Biology of tumour more important than primary site, say researchers

Scientists discover two new compounds that could help treat CF patients having common mutation

Study suggests relationship between smoking history, response to inhibiting PD-L1/PD-1 pathway

First Phase II study: Everolimus drug slows spread of advanced papillary kidney cancer

Scientists unravel secrets of mechanism that snips our genes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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