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Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

A little-used class of antidepressants appears potentially effective in combating a particularly deadly form of lung cancer, according to a new study from researchers at the Stanford University School of Medicine.

27 Sep 2013

Study shows how maternal viral infection may increase risk of having child with autism

Activating a mother's immune system during her pregnancy disrupts the development of neural cells in the brain of her offspring and damages the cells' ability to transmit signals and communicate with one another, researchers with the UC Davis Center for Neuroscience and Department of Neurology have found.

27 Sep 2013

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

The mood changes of a 'Jekyll-and-Hyde' protein, which sometimes boosts tumour cell growth and at other times suppresses it, have been explained in a new study led by Oxford University researchers.

27 Sep 2013

New ultra-specific test now available for prostate cancer

A new urine test for prostate cancer that measures minute fragments of RNA is now commercially available to men nationwide through the University of Michigan MLabs.

27 Sep 2013

Center of Reproductive Medicine announces participation in Thrive-IVF Research Study

The Center of Reproductive Medicine today announced its participation in the Thrive-IVF Research Study, a Phase 2 clinical trial sponsored by Nora Therapeutics, Inc., to evaluate the efficacy, safety and tolerability of NT100 in women who have had repeated in vitro fertilization (IVF) failures despite having good quality embryos.

26 Sep 2013

VolitionRx enters into distribution agreement with Active Motif for NuQ product line

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests for different types of cancer, today entered into an agreement with Active Motif, a leading provider of kits and reagents to enable epigenetics research.

26 Sep 2013

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

Three grants totaling more than $25 million over four years will help three research groups to develop authoritative information on the millions of genomic variants relevant to human disease and the hundreds that are expected to be useful for clinical practice. The awards are from the National Institutes of Health.

26 Sep 2013

MIT engineers develop nanoparticles that deliver cancer vaccines to lungs

Many viruses and bacteria infect humans through mucosal surfaces, such as those in the lungs, gastrointestinal tract and reproductive tract. To help fight these pathogens, scientists are working on vaccines that can establish a front line of defense at mucosal surfaces.

26 Sep 2013

Copenhagen researchers gain insight in molecular mechanisms behind breast cancer metastasis

Researchers at University of Copenhagen have gained more insight into the molecular mechanisms of importance for, for example, cancer cell growth and metastasis. The research objective is improved and more targeted drugs. The findings have just been published in the scientific journal Molecular Cell.

26 Sep 2013

Spanish scientists discover melatonin consumption helps control weight gain

Melatonin is a natural hormone segregated by the body and melatonin levels generally increase in the dark at night. It is also found in fruit and vegetables like mustard, Goji berries, almonds, sunflower seeds, cardamom, fennel, coriander and cherries.

26 Sep 2013

Scientist receives £58,000 from Alzheimer's Research UK to study chemical signals in AD

A University of Southampton scientist has just been awarded more than £58,000 by Alzheimer's Research UK to study chemical signals in the brain in Alzheimer's disease. The research will study the chemical signals that control learning and memory in an attempt to understand more about Alzheimer's and search for new treatments.

26 Sep 2013

MGH researchers identify rare gene mutations that appear to cause late-onset AD

Massachusetts General Hospital (MGH) researchers have identified and validated two rare gene mutations that appear to cause the common form of Alzheimer's disease (AD) that strikes after the age of 60.

25 Sep 2013

Researchers identify molecular pathway linking ICU ventilation to brain damage

At least 30 percent of patients in intensive care units (ICUs) suffer some form of mental dysfunction as reflected in anxiety, depression, and especially delirium. In mechanically-ventilated ICU patients, the incidence of delirium is particularly high, about 80 percent, and may be due in part to damage in the hippocampus, though how ventilation is increasing the risk of damage and mental impairment has remained elusive.

25 Sep 2013

Environmental enrichment protects against atrophy in chronic stages of TBI

For the first time, scientists at Toronto Rehab have found that in people with chronic moderate-severe traumatic brain injury (TBI), atrophy (shrinkage) in the brain may be countered by participating in environmental enrichment - increased physical, social and cognitive stimulation.

24 Sep 2013

Protein C News and Research

Study indicates that RNA translation is dictated by translational hotspots

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

Study shows how maternal viral infection may increase risk of having child with autism

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

New ultra-specific test now available for prostate cancer

Center of Reproductive Medicine announces participation in Thrive-IVF Research Study

VolitionRx enters into distribution agreement with Active Motif for NuQ product line

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

MIT engineers develop nanoparticles that deliver cancer vaccines to lungs

Copenhagen researchers gain insight in molecular mechanisms behind breast cancer metastasis

Spanish scientists discover melatonin consumption helps control weight gain

Scientist receives £58,000 from Alzheimer's Research UK to study chemical signals in AD

MGH researchers identify rare gene mutations that appear to cause late-onset AD

Researchers identify molecular pathway linking ICU ventilation to brain damage

Environmental enrichment protects against atrophy in chronic stages of TBI

Inflammatory marker may highlight aggressive RCC treatment need

Astrazeneca Licenses 3 X-Chem Drug Discovery Programs

Abbvie, Galapagos Ink Up To $405M CF Collaboration

Inflammation tracks mania course

Discovery could help develop new treatments for blood diseases

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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