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FDA accepts Merck's NOXAFIL IV solution NDA for priority review

Merck, known as MSD outside the United States and Canada, today announced that its New Drug Application for an investigational intravenous solution formulation of the company's antifungal agent, NOXAFIL (posaconazole), has been accepted for priority review by the U.S. Food and Drug Administration.

18 Nov 2013

Entire structure of health-care delivery needs to be re-engineered to address threat of antibiotic resistance

The entire structure of health-care delivery for effective antibiotics – from research and development, to distribution and rational use – needs to be re-engineered to address the looming global threat of antibiotic resistance, say the authors of a new report, published today [Sunday 17 November] in The Lancet Infectious Diseases, ahead of European Antibiotic Awareness Day, and the US Centers for Disease Control and Prevention (CDC) ‘Get Smart About Antibiotics Week’ on Monday 18 November.

18 Nov 2013

American Academy of Ophthalmology unveils comprehensive eye disease and condition patient database

The American Academy of Ophthalmology today unveiled the nation's first comprehensive eye disease and condition patient database. The IRIS Registry (Intelligent Research in Sight) made its debut in a presentation to 25,000 attendees during the opening session of the world's largest ophthalmic conference - the 117th Annual Meeting of the American Academy of Ophthalmology at the Ernest N. Morial Convention Center in New Orleans.

18 Nov 2013

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Findings by scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna reveal a surprising role for histone deacetylase 1 (HDAC1) - a member of a family of chromatin modifying proteins - in the development of skin tumors.

18 Nov 2013

Argos Soditic-managed funds announce acquisition of Cisbio Bioassays

The funds managed by Argos Soditic announce the acquisition, together with the management, of Cisbio Bioassays. This cutting-edge biotechnology company is the leader in the field of products and services for human in vitro diagnostics and pharmaceutical research.

18 Nov 2013

Research: Getting reminder texts helps patients take heart medicines more regularly

Getting reminder texts helped patients take their heart medicines (anti-platelet and cholesterol-lowering drugs) more regularly, according to research presented at the American Heart Association's Scientific Sessions 2013.

18 Nov 2013

Aligned approach to advanced bladder cancer treatment very much needed, study says

New study, involving eight Italian research centres, concluded that an aligned approach to the treatment of advanced bladder cancer is much needed, while confirming previously published results on survival estimates of associated salvage therapies.

18 Nov 2013

Researchers generate three-dimensional kidney structures from human stem cells

Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology.

18 Nov 2013

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Arvin Dar, PhD, structural and chemical biologist in oncological sciences at the Icahn School of Medicine at Mount Sinai, is one of 41 national recipients of the prestigious National Institutes of Health (NIH) Director's New Innovator Awards for High-Risk, High Reward Research. The award will support Dar's research into Ras-dependent cancers, specifically investigating how to combat mutations in Ras, a protein implicated in at least one of every five cancers.

16 Nov 2013

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

A protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells, according to new research out of the University of Minnesota. The findings could explain why nearly half of all patients infected with the AIDS virus experience some level of neurocognitive impairment.

16 Nov 2013

Researchers explain new function of 2 key molecules involved in tumor progression

Researchers from IMIM (Hospital del Mar Medical Research Institute) lead by Dr. Sandra Peir- have described a new function for two key molecules involved in tumor progression.

16 Nov 2013

Concordia University professors use funds to fight fungus and update aircraft

Thanks to new funding from the Government of Canada, two Concordia University professors just might create a greener aerospace industry and help cure fungal infections.

16 Nov 2013

Studies prove that students use prescription drugs to enhance cognitive performance

American and European studies prove that students use prescription medication or drugs to enhance their cognitive performance. Researchers from the universities of Zurich and Basel examined whether Swiss students have also experimented with neuroenhancement and which substances they take by conducting a survey of 6,725 students with an average age of 23 at the two universities and ETH Zurich.

16 Nov 2013

Scientists join patients to address Friedreich's Ataxia

The Spanish Federation of Ataxia (FEDAES)—in representation of the GENEFA Platform for a Friedreich's Ataxia cure—, the Babel Family association for biomedical research into Friedreich's Ataxia, the "Centro de Biología Molecular Severo Ochoa" (CMBSO), and the Institute for Research in Biomedicine (IRB Barcelona) have signed an agreement through which these patients' associations will fund, by means of donations, a 3-year research project addressing Friedreich's Ataxia.

16 Nov 2013

Quantitative models predict risk of acute urinary symptoms in prostate cancer patients treated with RT

An interim study by Italian researchers showed that using a modelling programme together with IPSS and dosage measure can predict the severity of acute urinary symptoms in patients with early prostate cancer who underwent radiotherapy.

16 Nov 2013

Scientists receive $2.2M grant to improve treatments for immune disorders, inflammatory diseases

Scientists from the Walter and Eliza Hall Institute have been awarded more than $2.2 million from the Australian Research Council (ARC) to improve treatments for immune disorders and inflammatory diseases.

16 Nov 2013

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Skin provides a first line of defense against viruses, bacteria and parasites that might otherwise make people ill. When an injury breaks that barrier, a systematic chain of molecular signaling launches to close the wound and re-establish the skin's layer of protection.

16 Nov 2013

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

The Joint Center for Cancer Precision Medicine, a collaborative initiative among Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, and the Broad Institute of MIT and Harvard, has been established to create "precision medicine treatment pathways" for patients with advanced cancers and to speed the development of personalized therapies.

16 Nov 2013

GO drug may improve outcome of bone marrow transplantation for select pediatric leukemia patients

Combining the drug gemtuzumab ozogamicin with conventional chemotherapy may improve the outcome of bone marrow transplantation for some children battling high-risk acute myeloid leukemia, according to a study led by St. Jude Children's Research Hospital. The results appear in the current edition of the journal Cancer.

16 Nov 2013

Diplomat selected as provider of IMBRUVICA capsules for MCL treatment

Diplomat, the country's largest independent specialty pharmacy, announced today it is one of five specialty pharmacies selected as a provider of IMBRUVICA (ibrutinib) capsules, approved Nov. 13 by the U.S. Food and Drug Administration for the treatment of Mantle Cell Lymphoma.

16 Nov 2013

Drugs News and Research

FDA accepts Merck's NOXAFIL IV solution NDA for priority review

Entire structure of health-care delivery needs to be re-engineered to address threat of antibiotic resistance

American Academy of Ophthalmology unveils comprehensive eye disease and condition patient database

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Argos Soditic-managed funds announce acquisition of Cisbio Bioassays

Research: Getting reminder texts helps patients take heart medicines more regularly

Aligned approach to advanced bladder cancer treatment very much needed, study says

Researchers generate three-dimensional kidney structures from human stem cells

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

Researchers explain new function of 2 key molecules involved in tumor progression

Concordia University professors use funds to fight fungus and update aircraft

Studies prove that students use prescription drugs to enhance cognitive performance

Scientists join patients to address Friedreich's Ataxia

Quantitative models predict risk of acute urinary symptoms in prostate cancer patients treated with RT

Scientists receive $2.2M grant to improve treatments for immune disorders, inflammatory diseases

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

GO drug may improve outcome of bone marrow transplantation for select pediatric leukemia patients

Diplomat selected as provider of IMBRUVICA capsules for MCL treatment

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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