Protein C News and Research

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Protein linked with asthma severity in children with high diesel exposure

A new study shows that exposure to diesel exhaust particles from traffic pollution leads to increased asthma severity in children. Moreover, the study finds that this is due to increased blood levels of IL-17A, a protein associated with several chronic inflammatory diseases, in children with high diesel exposure.

24 Sep 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

Scientists validate new system for identifying individuals with preclinical Alzheimer's disease

For years, scientists have attempted to understand how Alzheimer's disease harms the brain before memory loss and dementia are clinically detectable. Most researchers think this preclinical stage, which can last a decade or more before symptoms appear, is the critical phase when the disease might be controlled or stopped, possibly preventing the failure of memory and thinking abilities in the first place.

24 Sep 2013

Researchers discover drug that halts growth of brain tumor cells

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of - and ultimately left no detectable trace of - brain tumor cells taken from adult human patients.

24 Sep 2013

FDA approves STELARA (Ustekinumab) for treatment of active psoriatic arthritis

Janssen Biotech, Inc., announced today that the U.S. Food and Drug Administration (FDA) has approved STELARA® (ustekinumab) alone or in combination with methotrexate for the treatment of adult patients (18 years or older) with active psoriatic arthritis.

23 Sep 2013

Researchers lead two major trials to test potential treatments for asbestos-related cancer

University of Leicester researchers are leading two major trials into treatments for a type of cancer which affects those exposed to asbestos.

23 Sep 2013

New regulatory mechanism could help develop novel therapies for cancer

Molecular microbiologists at the University of Southern California (USC) have uncovered intricate regulatory mechanisms within the cell that could lead to novel therapeutics for the treatment of cancer and other diseases.

23 Sep 2013

Researchers report encouraging results from T1DAL study on type 1 diabetes

Encouraging results from the T1DAL study (Targeting effector memory T cells with alefacept in new onset type 1 diabetes), led by Mark R. Rigby MD, PhD from Indiana University and Riley Hospital for Children in Indianapolis and sponsored by the Immune Tolerance Network (ITN) with additional support from JDRF, are published today in The Lancet Diabetes & Endocrinology.

23 Sep 2013

New study on propofol drug may help develop effective anesthetics with fewer side effects

Researchers at Washington University School of Medicine in St. Louis and Imperial College London have identified the site where the widely used anesthetic drug propofol binds to receptors in the brain to sedate patients during surgery.

23 Sep 2013

Research on synapse stabilization aids understanding of autism, schizophrenia, intellectual disability

When we're born, our brains aren't very organized. Every brain cell talks to lots of other nearby cells, sending and receiving signals across connections called synapses.

21 Sep 2013

Researchers make new breakthroughs in brain circuitry controlling fertility

In a landmark discovery, the final piece in the puzzle of understanding how the brain circuitry vital to normal fertility in humans and other mammals operates has been put together by researchers at New Zealand's University of Otago.

21 Sep 2013

New cellular switch could eventually inhibit growth of aggressive malignant brain tumor

Researchers at UT Southwestern Medical Center have identified a cellular switch that potentially can be turned off and on to slow down, and eventually inhibit the growth of the most commonly diagnosed and aggressive malignant brain tumor.

21 Sep 2013

BASF Eyes Strategic Protein Growth, Buys Verenium For $62M

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20 Sep 2013

Antibody that binds, neutralizes HIV likely also targets the body's own self proteins

Researchers at The Scripps Research Institute discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines designed to elicit this protective antibody, called 4E10, and others like it, as doing so might be dangerous or inefficient.

20 Sep 2013

Small alteration in a brain gene contributes to risk for anxiety, depression and memory loss

Researchers at Weill Cornell Medical College have discovered why a tiny alteration in a brain gene, found in 20 percent of the population, contributes to the risk for anxiety, depression and memory loss.

20 Sep 2013

GW researcher awarded UO-1 grants to study gut microbiome on inflammation, cardiovascular disease

Dominic Raj, M.D., director of the division of nephrology and professor of medicine at the George Washington University School of Medicine and Health Sciences, was the recipient of two prestigious UO-1 grants from the National Institutes of Health.

20 Sep 2013

Dog food preservative may prevent nerve damage in patients taking chemotherapy

Working with cells in test tubes and in mice, researchers at Johns Hopkins have discovered that a chemical commonly used as a dog food preservative may prevent the kind of painful nerve damage found in the hands and feet of four out of five cancer patients taking the chemotherapy drug Taxol.

20 Sep 2013

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Researchers at A*STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers.

20 Sep 2013

Protein pair may be prognostic biomarker for identifying smoking-related lung cancers

Mayo Clinic researchers have shown that a specific protein pair may be a successful prognostic biomarker for identifying smoking-related lung cancers. The protein — ASCL1 — is associated with increased expression of the RET oncogene, a particular cancer-causing gene called RET. The findings appear in the online issue of the journal Oncogene.

20 Sep 2013

Drexel University researchers create molecule that can cause AIDS virus to destroy itself

Pinning down an effective way to combat the spread of the human immunodeficiency virus, the viral precursor to AIDS, has long been challenge task for scientists and physicians, because the virus is an elusive one that mutates frequently and, as a result, quickly becomes immune to medication.

20 Sep 2013

Protein C News and Research

Protein linked with asthma severity in children with high diesel exposure

Understanding genetic, physiological basis for metabolic diseases related to circadian function

Scientists validate new system for identifying individuals with preclinical Alzheimer's disease

Researchers discover drug that halts growth of brain tumor cells

FDA approves STELARA (Ustekinumab) for treatment of active psoriatic arthritis

Researchers lead two major trials to test potential treatments for asbestos-related cancer

New regulatory mechanism could help develop novel therapies for cancer

Researchers report encouraging results from T1DAL study on type 1 diabetes

New study on propofol drug may help develop effective anesthetics with fewer side effects

Research on synapse stabilization aids understanding of autism, schizophrenia, intellectual disability

Researchers make new breakthroughs in brain circuitry controlling fertility

New cellular switch could eventually inhibit growth of aggressive malignant brain tumor

BASF Eyes Strategic Protein Growth, Buys Verenium For $62M

Antibody that binds, neutralizes HIV likely also targets the body's own self proteins

Small alteration in a brain gene contributes to risk for anxiety, depression and memory loss

GW researcher awarded UO-1 grants to study gut microbiome on inflammation, cardiovascular disease

Dog food preservative may prevent nerve damage in patients taking chemotherapy

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Protein pair may be prognostic biomarker for identifying smoking-related lung cancers

Drexel University researchers create molecule that can cause AIDS virus to destroy itself

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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