Chromosome 7 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 7, one copy inherited from each parent, form one of the pairs. Chromosome 7 spans about 159 million DNA building blocks (base pairs) and represents more than 5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 7 likely contains about 1,150 genes.

Genes on chromosome 7 are among the estimated 20,000 to 25,000 total genes in the human genome.

New method designed to analyze the genes that regulate the immune system

Seattle scientists have developed a new method for analyzing the Major Histocompatibility Complex (MHC) of the human genome.

20 Apr 2006

Promising treatment for Huntington's disease soon to be tested clinically

At the Institut Curie, CNRS and Inserm researchers have shown that cysteamine, which is already used to treat a rare disease called cystinosis, prevents the death of neurons in Huntington's disease. Like Alzheimer's and Parkinson's, Huntington's disease, is characterized by the abnormal death of neurons.

19 Apr 2006

Researchers develop system for observing nuclear motion

The cell is understood to be highly organized, with specialized areas for different functions and molecular motors shuttling components around.

18 Apr 2006

First gene therapy human trial in the United States for a form of muscular dystrophy under way

The clinical trial for Duchenne muscular dystrophy (DMD) tests the safety and effectiveness of a therapy that was developed over two decades by scientists at the University of North Carolina Chapel Hill's School of Medicine and the University of Pittsburgh.

16 Apr 2006

Dasatinib provides significant benefit in chronic myeloid leukemia patients resistant to Gleevec

A study led by researchers from the Howard Hughes Medical Institute has found that dasatinib provides significant benefit in chronic myeloid leukemia (CML) patients resistant to Gleevec. (imatinib), according to a study presented during the 97th Annual Meeting of the American Association for Cancer Research.

11 Apr 2006

Researchers identify the role of a protein in hemoglobin gene silencing

Virginia Commonwealth University Massey Cancer Center researchers have identified the role of a protein in hemoglobin gene silencing that may one day be a potential target for the treatment of genetic blood disorders like sickle-cell anemia and beta-thalassemia on the molecular level.

11 Apr 2006

Researchers identify new disorder called cortical dysplasia-focal epilepsy syndrome

Researchers from the Translational Genomics Research Institute (TGen) and the Clinic for Special Children (CSC) in Strasburg, PA, have described a new childhood-onset disorder characterized by severe epilepsy and autistic traits, and identified its genetic basis.

11 Apr 2006

Minimal nutritional requirements for growing and maintaining human embryonic stem cells

Researchers at Yale have established the minimal nutritional requirements for growing and maintaining human embryonic stem cells, a recipe that is critical for clinical application and for developmental studies, according to a report in the Proceedings of the National Academy of Sciences.

11 Apr 2006

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

Inflammation, cartilage and bone erosions, joint destruction--that's the typical progression of arthritis and most rheumatic diseases.

4 Apr 2006

Weill Cornell experts publish review of genetic medicine

In an article published in the April issue of Nature Reviews Genetics, two experts at the Weill Medical College of Cornell University sum up the achievements, challenges and promise of a burgeoning field: genetic medicine.

3 Apr 2006

Malaria, mosquitoes and man - breaking a deadly cycle

Malaria kills a child every thirty seconds in Sub-Saharan Africa, according to recent estimates. It is a huge problem currently threatening over 40% of the world’s population and still on the increase.

31 Mar 2006

Weill Cornell researchers identify tumor-suppressor gene important to diffuse large B-cell lymphomas

Inactivation of a "tumor suppressor" gene could be a major cause of a class of blood cancers called diffuse large B-cell lymphomas, reports a team of researchers at the Weill Medical College of Cornell University.

30 Mar 2006

Procedure cures some diabetic mice, but not in the way previously reported

Researchers attempting to reproduce a controversial 2003 mouse experiment suggestive of a cure for type 1 diabetes have found evidence that the experimental procedure does eliminate diabetic symptoms in a small fraction of the mice exposed to it.

28 Mar 2006

Study provides a boost for efforts to reverse type-1 diabetes

Researchers have been able to confirm most but not all of the results of a high-profile study that brought new hope to diabetes patients. This study provides a boost for efforts to reverse type-1 diabetes in recently diagnosed patients but not for efforts to grow new islets from spleens.

27 Mar 2006

Chromosome 7 News and Research

New method designed to analyze the genes that regulate the immune system

Promising treatment for Huntington's disease soon to be tested clinically

Researchers develop system for observing nuclear motion

First gene therapy human trial in the United States for a form of muscular dystrophy under way

Dasatinib provides significant benefit in chronic myeloid leukemia patients resistant to Gleevec

Researchers identify the role of a protein in hemoglobin gene silencing

Researchers identify new disorder called cortical dysplasia-focal epilepsy syndrome

Minimal nutritional requirements for growing and maintaining human embryonic stem cells

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

Weill Cornell experts publish review of genetic medicine

Malaria, mosquitoes and man - breaking a deadly cycle

Weill Cornell researchers identify tumor-suppressor gene important to diffuse large B-cell lymphomas

Procedure cures some diabetic mice, but not in the way previously reported

Study provides a boost for efforts to reverse type-1 diabetes

Genetic differences between males and females might be evened out at the rim of the nucleus

Real-time molecule-by-molecule "movie" of protein production in live cells

Discovery of common genetic variation in an immune system gene that makes people much more likely to develop psoriasis

Cells have a natural defense against HIV

Sex chromosome genes influence aggression

SRY protein explains why men more likely to develop Parkinson's

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