Malignant News and Research

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Researchers identify ways to inhibit function of key protein linked to stem cell-like behavior in CML

A research team led by the Duke-NUS Graduate Medical School in Singapore has identified ways to inhibit the function of a key protein linked to stem cell-like behavior in terminal-stage chronic myeloid leukemia, making it possible to develop drugs that may extend the survival of these patients.

4 Jun 2013

Cytomegalovirus might accelerate the development of glioblastoma

A virus that infects most Americans but that usually remains dormant in the body might speed the progression of an aggressive form of brain cancer when particular genes are shut off in tumor cells, new research shows.

1 Jun 2013

International researchers find how brain cancer cells survive and drive tumor growth

An international team of researchers - led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine - has found that a singular gene mutation helps brain cancer cells to not just survive, but grow tumors rapidly by altering the splicing of genes that control cellular metabolism.

1 Jun 2013

University of Strathclyde uses new imaging technique to track nanomedicines' effects on patients

A pioneering imaging technique to track the effects of next-generation nanomedicines on patients has been harnessed by a University of Strathclyde academic.

31 May 2013

Raman spectroscopy algorithm has potential to diagnose breast lesions with high precision

A newly developed, single-step Raman spectroscopy algorithm has the potential to simultaneously detect microcalcifications and enable diagnosis of the associated breast lesions with high precision, according to data published in Cancer Research, a journal of the American Association for Cancer Research.

31 May 2013

Ruthenium complexes could pave way for cancer treatments, say UT Arlington researchers

A team of UT Arlington researchers has identified two ruthenium-based complexes they believe could pave the way for treatments that control cancer cell growth more effectively and are less toxic for patients than current chemotherapies.

30 May 2013

Digital chest tomosynthesis holds promise as first-line screening tool for lung cancer

Most lung cancers are detected when patients become symptomatic and have late-stage disease. However, recently, computed tomography creening for lung cancer has been reported to reduce lung cancer mortality.

29 May 2013

Liposomal anthracycline-based chemotherapy effective for children with leukemia: Study

Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added heart toxicity, according to the results of a study published online today in Blood, the Journal of the American Society of Hematology.

24 May 2013

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs before it's dissolved, researchers reported in an early online publication at Nature.

24 May 2013

SonaCare Medical highlights need for image-guided technologies to better identify prostate cancer

The need to add tissue preserving therapies to the prostate cancer treatment continuum was highlighted prominently at the 108th Annual Meeting of the American Urological Association, in San Diego.

24 May 2013

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induced by the oncogene BRAF, which usually appears mutated in melanoma and other cancers.

22 May 2013

Dean of Weill Cornell Medical College wins AWSM Award for Excellence

Dr. Laurie H. Glimcher, the Stephen and Suzanne Weiss Dean of Weill Cornell Medical College and provost for medical affairs of Cornell University, is the winner of a prestigious award from a group of female scientists from The Feinstein Institute for Medical Research dedicated to celebrating outstanding women in science and medicine.

22 May 2013

Research suggests that IMRT may not be more effective in patients who had prostatectomy

Intensity-modulated radiation therapy has become the most commonly used type of radiation in prostate cancer, but research from the University of North Carolina suggests that the therapy may not be more effective than older, less expensive forms of radiation therapy in patients who have had a prostatectomy.

22 May 2013

LDCT helps identify earliest stages of lung cancer

A study of veterans at high risk for developing lung cancer shows that low-dose computed tomography can be highly effective in helping clinicians spot tiny lung nodules which, in a small number of patients, may indicate the earliest stages of the disease.

22 May 2013

Researchers develop new mouse model to discover gene pathways that drive MPNST

University of Minnesota Medical School researchers from the Masonic Cancer Center, University of Minnesota, in partnership with the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors that allow them to discover new genes and gene pathways driving this type of cancer.

21 May 2013

Researchers identify novel biomarkers for predicting mortality in ICU patients

A metabolic profile of intensive care unit patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.

21 May 2013

Boston Scientific presents data on breakthrough products at Digestive Disease Week 2013

Boston Scientific Corporation is scheduled to participate in Digestive Disease Week 2013, May 18-21 in Orlando, Fla.

20 May 2013

Many Texas women who find abnormality on routine mammogram end up in surgical breast biopsy

Many women in Texas who are found to have an abnormality on routine mammogram or discover a lump in one of their breasts end up having an old-fashioned surgical biopsy to find out whether the breast abnormality is malignant.

17 May 2013

Researchers discover novel mechanism of tumor hypoxia

An article published recently in Tumor Microenvironment and Therapy - an open access journal by Versita, defines a novel mechanism of tumor hypoxia induced by the longitudinal gradient of residual oxygen along tumor vessels as they transverse the tumor.

10 May 2013

New research from Wake Forest Baptist looks at gene expression profiling in breast cancer

Predicting outcomes for cancer patients based on tumor-immune system interactions is an emerging clinical approach, and new research from Wake Forest Baptist Medical Center is advancing the field when it comes to the most deadly types of breast cancer.

10 May 2013

Malignant News and Research

Researchers identify ways to inhibit function of key protein linked to stem cell-like behavior in CML

Cytomegalovirus might accelerate the development of glioblastoma

International researchers find how brain cancer cells survive and drive tumor growth

University of Strathclyde uses new imaging technique to track nanomedicines' effects on patients

Raman spectroscopy algorithm has potential to diagnose breast lesions with high precision

Ruthenium complexes could pave way for cancer treatments, say UT Arlington researchers

Digital chest tomosynthesis holds promise as first-line screening tool for lung cancer

Liposomal anthracycline-based chemotherapy effective for children with leukemia: Study

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

SonaCare Medical highlights need for image-guided technologies to better identify prostate cancer

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

Dean of Weill Cornell Medical College wins AWSM Award for Excellence

Research suggests that IMRT may not be more effective in patients who had prostatectomy

LDCT helps identify earliest stages of lung cancer

Researchers develop new mouse model to discover gene pathways that drive MPNST

Researchers identify novel biomarkers for predicting mortality in ICU patients

Boston Scientific presents data on breakthrough products at Digestive Disease Week 2013

Many Texas women who find abnormality on routine mammogram end up in surgical breast biopsy

Researchers discover novel mechanism of tumor hypoxia

New research from Wake Forest Baptist looks at gene expression profiling in breast cancer

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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