Protein C News and Research

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New insights into lasso peptides offer promise for drug development

Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions

20 Sep 2024

Fever enhances immune cell activity and induces mitochondrial stress

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also - in a particular subset of T cells - cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

20 Sep 2024

New two-dose HIV vaccine strategy shows promise for stronger immune response

One major reason why it has been difficult to develop an effective HIV vaccine is that the virus mutates very rapidly, allowing it to evade the antibody response generated by vaccines.

20 Sep 2024

STING protein plays new role in cellular stress clearance and survival

A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell.

20 Sep 2024

Novel drug molecule offers hope for early Parkinson's disease treatment

A novel drug molecule could potentially lead to new treatments to prevent Parkinson's disease in younger patients, according to new research.

20 Sep 2024

Study reveals sex differences in T-cell responses among lung cancer patients

Researchers at Saint Louis University School of Medicine investigated differences in T-cell responses between male and female patients with lung cancer that may help direct future treatments.

20 Sep 2024

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Researchers examine how different dietary components affect the gut microbiome and development of non-communicable diseases.

20 Sep 2024

Childhood adversity linked to elevated health risks, differing by sex and stress

Researchers assess the heterogeneous effects of childhood adversity on disease biomarkers and health conditions in adulthood.

20 Sep 2024

Amyloid-β and tau disrupt brain activity, driving early cognitive decline in Alzheimer’s risk

Researchers discover how amyloid-β and tau pathologies interact to drive early neurophysiological changes and cognitive decline in older adults at risk of Alzheimer’s disease.

20 Sep 2024

Janus particles enable highly precise measurements in microfluidic devices

The importance of testing for diseases was thrust into the limelight during the COVID-19 pandemic. Many of us have undergone a PCR (Polymerase Chain Reaction) or ELISA (Enzyme-Linked Immunosorbent Assay) test within the past four years.

20 Sep 2024

Study reveals biomarkers that predict disability worsening in multiple sclerosis

A pioneering study presented today at ECTRIMS 2024 has identified critical biomarkers that can predict disability worsening in multiple sclerosis (MS).

19 Sep 2024

Philanthropic investment establishes research center to advance precision diagnosis for diseases

An outstanding $21 million philanthropic investment will establish a pioneering research center to advance precision diagnosis for diseases that affect millions of Australians.

19 Sep 2024

Brazilian vegans meet protein needs but rely on ultra-processed products, study shows

In an article published in JAMA Network Open, researchers at the University of São Paulo's Medical School (FM-USP) report on a study involving 774 men and women who followed a vegan diet in Brazil.

19 Sep 2024

Researchers identify bacterial strains to combat antibiotic-resistant gut infections

Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time.

19 Sep 2024

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Findings from the international FORT-2 clinical trial showed that a combination treatment including immunotherapy is safe and tolerable in patients with locally advanced or metastatic bladder cancer.

19 Sep 2024

Immune proteins in tooth enamel provide clues about ancient human health

A new way of looking at tooth enamel could give scientists a path to deeper understanding of the health of human populations, from the ancient to the modern.

19 Sep 2024

Collaborative study offers hope for syphilis vaccine development

Syphilis cases have surged worldwide, leaving public health officials scrounging for ways to stop the spread. Now, a large, collaborative study of syphilis genetics from four continents has found hints of a possible target for a vaccine.

19 Sep 2024

Adaptive platform trial tests multiple treatments for traumatic brain injury

Traumatic brain injury (TBI) results in close to 70,000 deaths in the United States every year, and it is the cause of long-term physical, cognitive and mental disability in 5 million Americans. But despite three decades of work, treatments are sorely lacking.

19 Sep 2024

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Investigating ECM changes in the hypothalamus reveals mechanisms behind insulin resistance, offering insights into obesity and metabolic disease treatment.

19 Sep 2024

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

A team of researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and The University of Texas M.D. Anderson Cancer Center, have reported safety and efficacy results from a Phase 1 trial that featured a personalized vaccine to treat lymphoplasmacytic lymphoma, a rare and slow-growing type of blood cancer, according to a study published recently in Nature Communications.

19 Sep 2024

Protein C News and Research

New insights into lasso peptides offer promise for drug development

Fever enhances immune cell activity and induces mitochondrial stress

New two-dose HIV vaccine strategy shows promise for stronger immune response

STING protein plays new role in cellular stress clearance and survival

Novel drug molecule offers hope for early Parkinson's disease treatment

Study reveals sex differences in T-cell responses among lung cancer patients

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Childhood adversity linked to elevated health risks, differing by sex and stress

Amyloid-β and tau disrupt brain activity, driving early cognitive decline in Alzheimer’s risk

Janus particles enable highly precise measurements in microfluidic devices

Study reveals biomarkers that predict disability worsening in multiple sclerosis

Philanthropic investment establishes research center to advance precision diagnosis for diseases

Brazilian vegans meet protein needs but rely on ultra-processed products, study shows

Researchers identify bacterial strains to combat antibiotic-resistant gut infections

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Immune proteins in tooth enamel provide clues about ancient human health

Collaborative study offers hope for syphilis vaccine development

Adaptive platform trial tests multiple treatments for traumatic brain injury

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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