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Cone snail venom could potentially treat severe forms of malaria

Severe forms of malaria such as Plasmodium falciparum may be deadly even after treatment with current parasite-killing drugs.

18 Feb 2021

Study reveals genetic signature of colibactin implicated in the development colorectal cancers

Escherichia coli bacteria are constitutive members of the human gut microbiota. However, some strains produce a genotoxin called colibactin, which is implicated in the development of colorectal cancer.

18 Feb 2021

Researchers develop new tool for tackling disseminated intravascular coagulation

Researchers have developed a new tool for addressing disseminated intravascular coagulation (DIC) - a blood disorder that proves fatal in many patients.

17 Feb 2021

Researchers develop a better solution to treat short bowel syndrome

Short Bowel Syndrome (SBS) is a medical disorder caused by a lack of a fully functional small intestine.

17 Feb 2021

Stability and pathogenicity of MERS coronavirus varies across different viral strains

An international team of researchers has conducted a study suggesting that individual variation across different strains of betacoronaviruses can alter their stability and pathogenicity profiles.

16 Feb 2021

Biodegradable microcapsules loaded with nerve growth factor can guide neuronal development

Researchers from Skoltech and their colleagues have demonstrated that nanoengineered biodegradable microcapsules can guide the development of hippocampal neurons in an in vitro experiment.

16 Feb 2021

Study outlines the reasons to test pediatric cancer patients for inherited genes

Because cancers in children are rare, many details about their biology remain unknown. In the field of cancer genetics, there's a limited understanding of how inherited genetic changes may contribute to the formation and growth of tumors.

16 Feb 2021

Artemisia plant extracts show potential anti-SARS-CoV-2 activity in vitro

A team of scientists from Germany and the USA recently explored the effectiveness of traditional plant medicines in treating SARS-CoV-2 infection.

16 Feb 2021

SARS-CoV-2 South Africa and Brazil variants show resistance to therapeutic antibodies

Scientists from Germany have determined the efficacy of currently used therapeutics in treating newer variants of SARS-CoV-2, including the UK, South Africa, and Brazil variants. Their findings reveal that both B.1.351 and B.1.1.248 variants are able to escape humoral immune responses induced by therapeutic antibodies, vaccinations, or natural SARS-CoV-2 infection.

15 Feb 2021

Nanobodies protect against SARS-CoV-2 variants in animal model

Nanobodies are a potential therapeutic strategy for treating COVID-19. While many previous studies report nanobodies active against SARS-CoV-2 in vitro, none have been evaluated via animal models' intranasal administration.

15 Feb 2021

New mouse model of SARS-CoV-2 infection reflects features of human infection

Now, a new preprint research paper posted to the bioRxiv server reports the development of a modified mouse model that allows productive SARS-CoV-2 infection of the mouse lungs, as well as the exploration of type I and III interferon responses in this condition.

14 Feb 2021

SARS-CoV-2's resistance to remdesivir in vitro

A new preprint research paper posted to the bioRxiv server discusses the emergence of mutations in the SARS-CoV-2 virus, allowing it to escape the effects of the most commonly used antiviral drug, remdesivir.

14 Feb 2021

Webinar: High-Content Imaging on Human Pluripotent Stem Cell Research

The upcoming webinar 'Visualizing Human Stem Cell Dynamics by Multicolor, Multiday High-Content Microscopy' will take place on February 17, 11 AM EST / 5 PM CET.

From Yokogawa Electric Corporation 12 Feb 2021

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

Scientists from Scientific and Educational Center & Smart Materials and Biomedical Applications under the leadership of Kateryna Levada together with colleagues from Center for Immunology and Cellular Biotechnology of the Immanuel Kant Baltic Federal University conducted a joint interdisciplinary study on the development of a new method for treating leukemia using nanomaterials.

11 Feb 2021

SARS-CoV-2 evolves antibody resistance in immunocompromised patient

Researchers in the United States who tracked the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an immunocompromised patient found that convalescent plasma therapy was associated with the emergence of viral variants that were less susceptible to neutralizing antibodies.

11 Feb 2021

Brain pericytes serve as a potential hub for SARS-CoV-2 infection

A team of scientists from the United States has recently conducted a study using pericyte-like cell-containing brain cortical organoids as an experimental model to investigate the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the central nervous system.

11 Feb 2021

New gut microbiome-based approach may have translational potential for cancer immunotherapy

Scientists from Nanjing University and the University of Macau have devised a new approach to extend the survival of transplanted probiotics in vivo, enhancing the efficacy of cancer chemo-/immunotherapies in mice.

11 Feb 2021

Second dose of Pfizer-BioNTech COVID-19 vaccine may not benefit previously infected individuals

Researchers at the NYU Grossman School of Medicine have shown that a second dose of the Pfizer-BioNTech BNT162b2 vaccine may not offer any additional protection against coronavirus disease 2019 (COVID-19) over one dose among individuals previously infected with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10 Feb 2021

Could Galectin-3 be a potential biomarker to help identify severe COVID-19 early?

Researchers have measured the galectin-3 levels in the sera of hospitalized patients. They found initial high levels indicate patients will become severely ill, suggesting it could be used as a predictor of severe disease.

10 Feb 2021

Polyclonal SARS-CoV-2 antibody shows potent neutralizing activity in vitro

Researchers shows a fully human immunoglobulin (IgG) that potently inhibits SARS-CoV-2 infection.

10 Feb 2021

in vitro News and Research

Cone snail venom could potentially treat severe forms of malaria

Study reveals genetic signature of colibactin implicated in the development colorectal cancers

Researchers develop new tool for tackling disseminated intravascular coagulation

Researchers develop a better solution to treat short bowel syndrome

Stability and pathogenicity of MERS coronavirus varies across different viral strains

Biodegradable microcapsules loaded with nerve growth factor can guide neuronal development

Study outlines the reasons to test pediatric cancer patients for inherited genes

Artemisia plant extracts show potential anti-SARS-CoV-2 activity in vitro

SARS-CoV-2 South Africa and Brazil variants show resistance to therapeutic antibodies

Nanobodies protect against SARS-CoV-2 variants in animal model

New mouse model of SARS-CoV-2 infection reflects features of human infection

SARS-CoV-2's resistance to remdesivir in vitro

Webinar: High-Content Imaging on Human Pluripotent Stem Cell Research

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

SARS-CoV-2 evolves antibody resistance in immunocompromised patient

Brain pericytes serve as a potential hub for SARS-CoV-2 infection

New gut microbiome-based approach may have translational potential for cancer immunotherapy

Second dose of Pfizer-BioNTech COVID-19 vaccine may not benefit previously infected individuals

Could Galectin-3 be a potential biomarker to help identify severe COVID-19 early?

Polyclonal SARS-CoV-2 antibody shows potent neutralizing activity in vitro

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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