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Diets and the famine reaction: an interview with Associate Professor Amanda Salis, University of Sydney

The statistic that you often hear is that 95% of diets fail, but in actual fact, emerging research is now showing that it’s around 70% of diets that fail. That means that around 30% of people who are losing weight are actually keeping it off. So we’re doing better now than we were doing in the past, but there’s still work to be done.

7 Nov 2013

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

Despite high expectations for the commonly used diabetes drug metformin to improve risk factors for heart disease in people without diabetes, few beneficial effects have been found in a randomised trial of patients with established cardiovascular disease, published in The Lancet Diabetes & Endocrinology.

7 Nov 2013

Inhibition of heart protein reduces damage from heart attack, say researchers

The stop and start of blood flow to the heart during and after a heart attack causes severe damage to heart cells, reducing their capacity to function and potentially causing their death.

7 Nov 2013

Linagliptin shows efficacy, tolerability in adults with T2D and liver disease

Boehringer Ingelheim and Eli Lilly and Company announce new data that reinforce the efficacy and tolerability of linagliptin in people with Type 2 Diabetes and liver disease, as well as Asian people with T2D aged 65 years or older.

7 Nov 2013

Researchers identify new class of anti-inflammatory drugs may be used to treat IBD

Researchers in UCD Conway Institute and Systems Biology Ireland have identified a way that a new class of anti-inflammatory drugs may be used to treat inflammatory bowel disease (IBD).

7 Nov 2013

Stroke patients treated at hospitals with neurology residency programs benefit from tPA drugs

Stroke patients treated at hospitals with neurology residency programs are significantly more likely to get life-saving clot-busting drugs than those seen at other teaching or non-teaching hospitals, new Johns Hopkins-led research suggests.

7 Nov 2013

Patrys receives FDA Orphan Medicinal Product Designation for PAT-SM6

Patrys Limited, a clinical stage biotechnology company, has received confirmation of Orphan Medicinal Product Designation for its lead anti-cancer product PAT-SM6, from the USA Food and Drugs Administration.

7 Nov 2013

New hand-held device can help prevent thousands of unnecessary TB deaths

Thousands of deaths from tuberculosis, an infectious bacterial disease, could be prevented using a new hand-held device that is being developed to detect potentially fatal drug resistance in less than 15 minutes.

7 Nov 2013

Investigators find potential new target for treatment of low-grade gliomas

Investigators at Johns Hopkins have found a known genetic pathway to be active in many difficult-to-treat pediatric brain tumors called low-grade gliomas, potentially offering a new target for the treatment of these cancers.

7 Nov 2013

Utah pathologist receives prestigious Packard Foundation award for research on good bacteria

Bacteria have a bad reputation, but University of Utah pathologist June L. Round, Ph.D., likes to look at their good side-and for the second time this year she's received a prestigious national award to aid her research into bacteria that actually are good for human health.

7 Nov 2013

Simple urine test can help identify disease risks in young type 1 diabetes patients

Using a simple urine test, researchers can now identify young people with type 1 diabetes at risk of heart and kidney disease. The new research, funded by JDRF, Diabetes UK, and the British Heart Foundation, was published today, 06 November, in the journal Diabetes Care.

7 Nov 2013

Researchers discover relationship between TGFb signalling pathways and CXCR4 in HCC

Researchers from the Biological clues of the invasive and metastatic phenotype group of the Bellvitge Biomedical Research Institute (IDIBELL) led by Isabel Fabregat have discovered the relationship between the TGFb signalling pathways and CXCR4 in hepatocellular carcinoma (HCC) .

7 Nov 2013

New study uses genomic sequencing to develop treatments for castration-resistant prostate cancer

A new study at Mayo Clinic is using genomic sequencing to develop customized treatments for men with castration-resistant prostate cancer, a progressive and incurable stage of prostate cancer, which no longer responds to hormone therapies that stop or slow testosterone production.

7 Nov 2013

Cocaine addicts may become trapped in drug binges due to emotional lows, says study

Cocaine addicts may become trapped in drug binges - not because of the euphoric highs they are chasing but rather the unbearable emotional lows they desperately want to avoid.

7 Nov 2013

Study: Increased duration of breastfeeding could be associated with decreased incidence of autism

In an article appearing in Medical Hypotheses on September 20, a New York-based physician-researcher from the Touro College of Osteopathic Medicine has called for the testing of umbilical cord blood for levels of a growth protein that could help predict an infant's propensity to later develop autism.

6 Nov 2013

Normal blood sugar regulation depends on partnership between pancreas and brain

A growing body of evidence suggests that the brain plays a key role in glucose regulation and the development of type 2 diabetes, researchers write in the Nov. 7 issue of the journal Nature.

6 Nov 2013

Advanced prostate cancer therapies: an interview with Dr. Nancy Dawson, Lombardi Comprehensive Cancer Center

The prostate gland produces part of the seminal fluid that protects sperm. It is located in front of the rectum and under the bladder, and surrounds the urethra, the tube through which urine flows from the bladder to and out of the penis.

6 Nov 2013

New app now in handy pocket format to help ex-drug and alcohol abusers

Ex-drug and alcohol abusers who have completed their treatment need a simple support system and daily motivation. Now they are getting both - in a handy pocket format.

6 Nov 2013

New drug combination therapy effectively kills cancer cells

Results from a recent preclinical study have shown that a new drug combination therapy being developed at Virginia Commonwealth University Massey Cancer Center effectively killed colon, liver, lung, kidney, breast and brain cancer cells while having little effect on noncancerous cells. The results lay the foundation for researchers to plan a future phase 1 clinical trial to test the safety of the therapy in a small group of patients.

6 Nov 2013

ADC Therapeutics, Five Prime sign exclusive license agreement for human antibodies

ADC Therapeutics Sarl, a portfolio company of Auven Therapeutics and the oncology drug development company specializing in proprietary antibody drug conjugates, and Five Prime Therapeutics, Inc., a clinical-stage biotechnology company focused on discovering and developing novel protein therapeutics for cancer and inflammatory diseases, today announced an exclusive license agreement for human antibodies directed to an undisclosed target expressed on the surface of various types of cancers.

6 Nov 2013

Drugs News and Research

Diets and the famine reaction: an interview with Associate Professor Amanda Salis, University of Sydney

Study finds few beneficial effects of metformin drug for cardiovascular disease in people without diabetes

Inhibition of heart protein reduces damage from heart attack, say researchers

Linagliptin shows efficacy, tolerability in adults with T2D and liver disease

Researchers identify new class of anti-inflammatory drugs may be used to treat IBD

Stroke patients treated at hospitals with neurology residency programs benefit from tPA drugs

Patrys receives FDA Orphan Medicinal Product Designation for PAT-SM6

New hand-held device can help prevent thousands of unnecessary TB deaths

Investigators find potential new target for treatment of low-grade gliomas

Utah pathologist receives prestigious Packard Foundation award for research on good bacteria

Simple urine test can help identify disease risks in young type 1 diabetes patients

Researchers discover relationship between TGFb signalling pathways and CXCR4 in HCC

New study uses genomic sequencing to develop treatments for castration-resistant prostate cancer

Cocaine addicts may become trapped in drug binges due to emotional lows, says study

Study: Increased duration of breastfeeding could be associated with decreased incidence of autism

Normal blood sugar regulation depends on partnership between pancreas and brain

Advanced prostate cancer therapies: an interview with Dr. Nancy Dawson, Lombardi Comprehensive Cancer Center

New app now in handy pocket format to help ex-drug and alcohol abusers

New drug combination therapy effectively kills cancer cells

ADC Therapeutics, Five Prime sign exclusive license agreement for human antibodies

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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