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Newly identified microRNA impedes malignancy of tumor cells and metastasis

Cancer cells can reactivate a cellular process that is an essential part of embryonic development. This allows them to leave the primary tumor, penetrate the surrounding tissue and form metastases in peripheral organs.

27 Oct 2017

Drexel researchers pinpoint new targets for treating chronic lung disease in premature infants

Researchers at Drexel University have revealed that inhibiting the micro-RNA miR-34a significantly reduces bronchopulmonary dysplasia (BPD) in mice.

27 Oct 2017

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

Researchers at Linköping University in Sweden have discovered a previously unknown molecular binding site that can influence electrical impulses in nerves.

27 Oct 2017

Study into killer T-cell activity could provide roadmap for tackling antibiotic resistance

In a study that could provide a roadmap for combatting the rising threat of drug-resistant pathogens, researchers have discovered the specific mechanism the body's T cells use to kill bacteria.

27 Oct 2017

Researchers find link between disrupted energy production and late-onset Alzheimer's disease

A team of investigators from McLean Hospital and Harvard Medical School, led by Kai C. Sonntag, MD, PhD, and Bruce M. Cohen, MD, PhD, has found a connection between disrupted energy production and the development of late-onset Alzheimer's disease (LOAD). The findings appear in the current issue of Scientific Reports.

27 Oct 2017

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Precision Medicine in oncology, where genetic testing is used to determine the best drugs to treat cancer patients, is not always so precise when applied to some of the world's more diverse populations, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope, and the Keck School of Medicine of the University of Southern California.

27 Oct 2017

Sleeper cells in cancerous tumors can be destroyed if they possess specific defects

In many metastasized types of cancer, disseminated tumors grow back despite successful chemotherapy. As a research team under the direction of the University of Bern, Switzerland, has now discovered, this is because of isolated cancer cells that survive the chemotherapy due to a phase of dormancy.

27 Oct 2017

New device that fits on a key chain can accurately test for allergens

More than 50 million Americans have food allergies and often just trace amounts of allergens can trigger life-threatening reactions.

26 Oct 2017

Research advance may lead to preservation of hearing in people with Usher syndrome type III

A research advance co-led by Case Western Reserve University School of Medicine's Kumar Alagramam, PhD, may stop the progression of hearing loss and lead to significant preservation of hearing in people with Usher syndrome type III, a form of hereditary hearing loss linked to defects in the sensory "hair" cells in the inner ear. USH3 is caused by a mutation in the clarin-1 gene.

26 Oct 2017

Penn study sheds light on genetic cause of early hearing loss

From the moment a baby is born, they are put through a battery of screenings to test for all sorts of characteristics, which includes the sense of hearing.

26 Oct 2017

Scientists define molecular mechanism that triggers pump-induced disease

Researchers at Texas Tech University Health Sciences Center investigated a pump-induced disease and defined the molecular mechanism that triggers it. The study, "On the effect of hyperaldosteronism-inducing mutations in Na/K pumps," was published in the October issue of the Journal of General Physiology.

26 Oct 2017

Dartmouth study uncovers three novel genetic biomarkers for lung cancer

Both environmental and genetic risk factors contribute to development of lung cancer. Tobacco smoking is the most well-known environmental risk factor associated with lung cancer. A Dartmouth research team led by Yafang Li, PhD, has conducted a study to display that gene-smoking interactions play important roles in the etiology of lung cancer.

26 Oct 2017

Penn study shows how blood flow shapes developing heart valves into mature valve leaflets

Congenital heart valve defects appear in 2 percent of all live births, making them the most common type of birth defect. While some of these defects have been linked to specific genetic mutations, the majority have no clearly definable genetic cause, suggesting that epigenetic factors - changes in gene expression versus an alteration in the genetic code -- play an important role.

26 Oct 2017

Wayne State researchers win NIH grant to uncover new antibiotic targets

A research team from Wayne State University has received a $1.85 million grant from the National Institute of General Medical Sciences of the National Institutes of Health for the project "Mechanisms of Non-Shine-Dalgarno Translation Initiation."

26 Oct 2017

High intensity exercise training may reduce chances of developing colon cancer

Population studies strongly suggest that colon cancer risk is reduced in those who are physically active. Enlarged crypt lesions in the colon are early signs of increasing risk of colon cancer.

26 Oct 2017

New enzyme may one day enable genome surgery that erases harmful mutations

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A•T to a G•C.

26 Oct 2017

Survival of early stage lung cancer patients improves with advancement in surgery, radiation

With the advancement of surgical and radiation therapy strategies for stage 1 non-small-cell lung cancer (NSCLC), more patients are being treated, resulting in higher survival rates, according to a study published online today in The Annals of Thoracic Surgery.

26 Oct 2017

Timing of DNA damage within checkpoints matters to a cell's fate, study reports

DNA damage occurs routinely within your cells due to sun exposure, smoking and sometimes during the normal process of making new DNA.

26 Oct 2017

JGU researchers develop new technique to facilitate differentiation of stem cells into neurons

Very little is still known about how neurons can be generated from stem cells. Researchers at the University Medical Center of Johannes Gutenberg University Mainz have now developed a promising technique that will facilitate the differentiation of stem cells into neurons. This even enables them to accelerate the maturation process.

26 Oct 2017

Study: New histone modifications link cellular metabolism to chromatin architecture

Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published in 'Nature Structural and Molecular Biology'.

26 Oct 2017

B Cell News and Research

Newly identified microRNA impedes malignancy of tumor cells and metastasis

Drexel researchers pinpoint new targets for treating chronic lung disease in premature infants

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

Study into killer T-cell activity could provide roadmap for tackling antibiotic resistance

Researchers find link between disrupted energy production and late-onset Alzheimer's disease

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Sleeper cells in cancerous tumors can be destroyed if they possess specific defects

New device that fits on a key chain can accurately test for allergens

Research advance may lead to preservation of hearing in people with Usher syndrome type III

Penn study sheds light on genetic cause of early hearing loss

Scientists define molecular mechanism that triggers pump-induced disease

Dartmouth study uncovers three novel genetic biomarkers for lung cancer

Penn study shows how blood flow shapes developing heart valves into mature valve leaflets

Wayne State researchers win NIH grant to uncover new antibiotic targets

High intensity exercise training may reduce chances of developing colon cancer

New enzyme may one day enable genome surgery that erases harmful mutations

Survival of early stage lung cancer patients improves with advancement in surgery, radiation

Timing of DNA damage within checkpoints matters to a cell's fate, study reports

JGU researchers develop new technique to facilitate differentiation of stem cells into neurons

Study: New histone modifications link cellular metabolism to chromatin architecture

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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