Protein C News and Research

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New type of cancer immunotherapy harnesses body's immune system to attack tumors

By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy—harnessing the body's immune system to attack tumors. To accomplish this, they had to thread a needle in immune function, shrinking tumors without triggering unwanted autoimmune responses.

19 Aug 2013

Scientists reveal how females select 'right' sperm to fertilize their eggs

University of East Anglia scientists have revealed how females select the 'right' sperm to fertilize their eggs when faced with the risk of being fertilized by wrong sperm from a different species.

19 Aug 2013

Secondary cancers in melanoma patients treated for BRAF gene mutation require new strategies

Moffitt Cancer Center researchers suggest secondary cancers seen in melanoma patients who are being treated for a BRAF gene mutation may require new strategies, such as enhanced surveillance and combining BRAF-inhibitor therapy with other inhibitors, especially as they become more widely used.

17 Aug 2013

Interactions between sympathetic neurons and pancreatic cells have implications for organ development

The human body is a complicated system of blood vessels, nerves, organs, tissue and cells each with a specific job to do. When all are working together, it's a symphony of form and function as each instrument plays its intended roles.

17 Aug 2013

Study suggests Braintone has neuroprotective effects on ischemia-induced brain damage

Recently, the importance of the neurovascular unit, which is comprised of neurons, endothelial cells and astrocytes, has received great attention in the field of stroke, because stroke affects not only neurons, but also astrocytes and microvessels.

17 Aug 2013

Arrays of nanoscale sensors detect flaws in drugs and help improve production

MIT chemical engineers have discovered that arrays of billions of nanoscale sensors have unique properties that could help pharmaceutical companies produce drugs - especially those based on antibodies - more safely and efficiently.

17 Aug 2013

UCSF study shows potential for new treatment strategy for Parkinson’s disease

UC San Francisco scientists working in the lab used a chemical found in an anti-wrinkle cream to prevent the death of nerve cells damaged by mutations that cause an inherited form of Parkinson-s disease.

17 Aug 2013

ATSP-7041 stapled peptide activates p53, suppresses tumor growth in animal models

Aileron Therapeutics, Inc., a clinical stage biopharmaceutical company that is developing first-in-class therapeutics based on its proprietary Stapled Peptide drug platform, announced today the publication of preclinical data on ATSP-7041, a potent and selective stapled peptide re-activator of the wild type p53 tumor suppressor protein.

17 Aug 2013

Michigan researchers use TACC supercomputers to understand DNA bending, repair mechanisms

The biological information that makes us unique is encoded in our DNA. DNA damage is a natural biological occurrence that happens every time cells divide and multiply. External factors such as overexposure to sunlight can also damage DNA.

17 Aug 2013

DLBCLs resistant to chemotherapy can be reprogrammed to respond using azacitidine

A phase I clinical trial showed diffuse, large B-cell lymphomas (DLBCLs) resistant to chemotherapy can be reprogrammed to respond to treatment using the drug azacitidine, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

17 Aug 2013

Inflating blood pressure cuff ahead of heart bypass surgery reduces heart injury

Inflating a blood pressure cuff on the upper arm just ahead of heart bypass surgery reduces heart injury and might even improve bypass patients’ long-term survival, according to an Article published in The Lancet.

16 Aug 2013

Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease

Mad cow disease and its cousin Creutzfeld-Jakob disease cause fatal spongy changes in brain tissue. Today, we know that these diseases are caused by prions, proteins that are folded incorrectly. A team of German researchers have now been able to follow how the diseased proteins aggregate and "infect" healthy ones on the atomic scale. Their report appears in the journal Angewandte Chemie.

16 Aug 2013

Scientists shed new light on molecular causes of age related degenerative disease

An international collaboration jointly led by scientists from Trinity College Dublin has shed new light on the origins and molecular causes of age related degenerative conditions including Motor Neurone Disease (MND). The new perspective provided by this work may lead the way to new treatments and early diagnoses.

16 Aug 2013

New UV-visible spectrophotometer released by Hitachi High Technologies America, Inc.

The Life Sciences Division of Hitachi High Technologies America, Inc. released its newest UV-visible spectrophotometer, Model UH5300.

16 Aug 2013

Kinetin stops the effects of Parkinson's disease on brain cells, say scientists

The active ingredient in an over-the-counter skin cream might do more than prevent wrinkles. Scientists have discovered that the drug, called kinetin, also slows or stops the effects of Parkinson's disease on brain cells.

16 Aug 2013

Researchers define role of vinculin protein in enabling cell mobility

Researchers at the University of North Carolina and the National Institutes for Health have defined the role of the protein vinculin in enabling cell movement.

16 Aug 2013

Researchers discover how common oral bacterium can contribute to colorectal cancer

Researchers from Case Western Reserve University School of Dental Medicine have discovered how a common oral bacterium can contribute to colorectal cancer, a finding that opens promising new research avenues for the development of approaches to prevent and treat the disease.

16 Aug 2013

TSRI scientists discover molecular mechanism by which deadly Ebola virus assembles

Scientists at The Scripps Research Institute (TSRI) have discovered the molecular mechanism by which the deadly Ebola virus assembles, providing potential new drug targets.

16 Aug 2013

Scientists uncover potential drug target for effective therapy against bacterial disease brucellosis

UC Davis scientists have uncovered a potential drug target for the development of an effective therapy against the debilitating, chronic form of the bacterial disease brucellosis, which primarily afflicts people in Mediterranean and Middle Eastern countries.

16 Aug 2013

UCLA receives $5M from NIH to develop tool for detecting stomach cancer

Imagine having a sample of your saliva taken at the dentist's office, and then learning within minutes whether your risk for stomach cancer is higher than normal. That futuristic-sounding scenario may actually not be too far from reality.

16 Aug 2013

Protein C News and Research

New type of cancer immunotherapy harnesses body's immune system to attack tumors

Scientists reveal how females select 'right' sperm to fertilize their eggs

Secondary cancers in melanoma patients treated for BRAF gene mutation require new strategies

Interactions between sympathetic neurons and pancreatic cells have implications for organ development

Study suggests Braintone has neuroprotective effects on ischemia-induced brain damage

Arrays of nanoscale sensors detect flaws in drugs and help improve production

UCSF study shows potential for new treatment strategy for Parkinson’s disease

ATSP-7041 stapled peptide activates p53, suppresses tumor growth in animal models

Michigan researchers use TACC supercomputers to understand DNA bending, repair mechanisms

DLBCLs resistant to chemotherapy can be reprogrammed to respond using azacitidine

Inflating blood pressure cuff ahead of heart bypass surgery reduces heart injury

Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease

Scientists shed new light on molecular causes of age related degenerative disease

New UV-visible spectrophotometer released by Hitachi High Technologies America, Inc.

Kinetin stops the effects of Parkinson's disease on brain cells, say scientists

Researchers define role of vinculin protein in enabling cell mobility

Researchers discover how common oral bacterium can contribute to colorectal cancer

TSRI scientists discover molecular mechanism by which deadly Ebola virus assembles

Scientists uncover potential drug target for effective therapy against bacterial disease brucellosis

UCLA receives $5M from NIH to develop tool for detecting stomach cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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