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UC San Diego researchers develop 3D visualization tool for mapping omics data onto organs

University of California San Diego researchers have developed the first 3D spatial visualization tool for mapping "'omics" data onto whole organs.

20 Oct 2017

Researchers use nanopore technique to detect biomarkers of disease

Adam Hall, Ph.D., isn't kidding when he says the research he does is on a very small scale. But he is understating things more than just a little.

20 Oct 2017

New synthetic genetic tool measures and manipulates protein aggregation in live cells

A common thread ties seemingly unlinked disorders like Alzheimer's disease and type II diabetes together. This thread is known as protein aggregation and happens when proteins clump together. These complexes are a hallmark of many diseases but have recently been linked to beneficial functions as well.

20 Oct 2017

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

Phospholipids - fat molecules that form the membranes found around cells - make up almost half of the dry weight of cells, but when it comes to autoimmune diseases, their role has largely been overlooked.

20 Oct 2017

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in cells of the immune system could be a strategy to treat inflammatory lung disease.

20 Oct 2017

Study unlocks complexities of cell death process that plays key role in health and disease

University of Pittsburgh scientists are unlocking the complexities of a recently discovered cell death process that plays a key role in health and disease, and new findings link their discovery to asthma, kidney injury, and brain trauma.

20 Oct 2017

Dana-Farber, Brigham and Women's Cancer Center certified to offer new CAR T-cell therapy

Following a successful clinical trial involving Dana-Farber Cancer Institute and Brigham and Women's Hospital, the first chimeric antigen receptor (CAR) T-cell therapy for adult cancers was approved by the Food and Drug Administration today.

20 Oct 2017

Gene circuit can be used to switch on inside cancer cells and stimulate immune attack, study suggests

A new study, conducted by researchers at MIT, suggests that a recently developed synthetic gene circuit can stimulate the immune system to kill cancer cells when it identifies indications of the cancer. The gene circuit will only stimulate a therapeutic response when it identifies two particular cancer markers.

20 Oct 2017

Chromosomes may be entangled, research finds

Everyone knows that long bits of yarn, or charging cables and the like, tend to get quickly tangled and form nasty knots. Little is known about the structures of our genetic material, chromosomes, which also consist of long strings that -- according to our experience -- should be likely to become knotted. However, up to now it has not been possible to study this experimentally.

20 Oct 2017

Findings suggest e-cigarettes may be just as bad as traditional cigarettes

E-cigarettes appear to trigger unique immune responses as well as the same ones that cigarettes trigger that can lead to lung disease, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

20 Oct 2017

Adipose-derived stem cell clinical trial focuses on non-healing leg wounds

Sanford Health is launching its second adipose-derived stem cell clinical trial - this one to focus on non-healing leg wounds.

20 Oct 2017

Researchers discover new function in gene-regulatory protein

Researchers at Umeå and Stockholm universities in Sweden and Johns Hopkins University School of Medicine in the US have published a new study in the journal Molecular Cell.

20 Oct 2017

Researchers reveal how certain nerves sustain prostate cancer growth

In a study in today's issue of Science, researchers at Albert Einstein College of Medicine, part of Montefiore Medicine, report that certain nerves sustain prostate cancer growth by triggering a switch that causes tumor vessels to proliferate.

20 Oct 2017

New CAR-T cell therapy offers effective option for certain blood cancer patients

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis is one of the first centers nationwide to offer a new immunotherapy that targets certain blood cancers.

19 Oct 2017

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Researchers say they have found the "first direct biological evidence" of damage in veterans with Gulf War illness to DNA within cellular structures that produce energy in the body.

19 Oct 2017

Small RNA molecules trigger cancer cells to commit suicide

Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.

19 Oct 2017

Penn researchers functionally dissect gene variant linked to FTLD

Seven years ago, Penn Medicine researchers showed that mutations in the TMEM106B gene significantly increased a person's risk of frontotemporal lobar degeneration (FTLD), the second most common cause of dementia in those under 65.

19 Oct 2017

New research provides insights into role of key cancer gene

New research represents a promising step towards better understanding of a key cancer gene. A long-running collaboration between researchers at the Babraham Institute, Cambridge, and the AstraZeneca IMED Biotech Unit reveals new insights into how the PTEN gene may control cell growth and behavior and how its loss contributes to the development and advancement of certain cancers.

19 Oct 2017

Scientists uncover surprising molecular link in critical cellular growth pathway

A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth.

19 Oct 2017

New procedure expands options open for carrying out tests on human brain cells

Researchers at the University of Tübingen have become the first to keep human brain tissue alive outside the body for several weeks.

19 Oct 2017

B Cell News and Research

UC San Diego researchers develop 3D visualization tool for mapping omics data onto organs

Researchers use nanopore technique to detect biomarkers of disease

New synthetic genetic tool measures and manipulates protein aggregation in live cells

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

Study unlocks complexities of cell death process that plays key role in health and disease

Dana-Farber, Brigham and Women's Cancer Center certified to offer new CAR T-cell therapy

Gene circuit can be used to switch on inside cancer cells and stimulate immune attack, study suggests

Chromosomes may be entangled, research finds

Findings suggest e-cigarettes may be just as bad as traditional cigarettes

Adipose-derived stem cell clinical trial focuses on non-healing leg wounds

Researchers discover new function in gene-regulatory protein

Researchers reveal how certain nerves sustain prostate cancer growth

New CAR-T cell therapy offers effective option for certain blood cancer patients

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Small RNA molecules trigger cancer cells to commit suicide

Penn researchers functionally dissect gene variant linked to FTLD

New research provides insights into role of key cancer gene

Scientists uncover surprising molecular link in critical cellular growth pathway

New procedure expands options open for carrying out tests on human brain cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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