Protein C News and Research

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Scientists discover biomarker that helps physicians predict how well cancer patients respond to drugs

A team of scientists led by Associate Professor Zeng Qi from A*STAR's Institute of Molecular and Cell Biology (IMCB) have discovered a new biomarker which will help physicians predict how well cancer patients respond to cancer drugs.

7 Aug 2013

Researchers identify specific genetic mutations that contribute to disorders of brain development

A collaborative team of researchers including scientists from UCLA has uncovered evidence that a specific genetic alteration appears to contribute to disorders of brain development, including schizophrenia. They also found that schizophrenia shares a common biological pathway with Fragile X mental retardation syndrome, a disorder associated with both intellectual impairment and autism.

7 Aug 2013

Combining drugs that target AXL and ErbB receptors could offer better way to fight tumors

Cancer drugs known as ErbB inhibitors have shown great success in treating many patients with lung, breast, colon and other types of cancer. However, ErbB drug resistance means that many other patients do not respond, and even among those who do, tumors commonly come back.

7 Aug 2013

Ensemble Therapeutics initiates research and development collaboration with Novartis

Ensemble Therapeutics, a biotechnology company developing Ensemblins, a novel class of small molecule therapeutics with the power of biologics, today announced the initiation of a two-part research and development collaboration with Novartis.

6 Aug 2013

New studies in mice support toxic role of aluminum in neurodegenerative conditions

Investigators have linked aluminum accumulation in the brain as a possible contributing factor to neurodegenerative disorders such as Alzheimer's disease. A new study published in Restorative Neurology and Neuroscience sheds light on the mechanism underlying aluminum-induced neuronal cell death and identifies necrostatin-1 as a substance which counteracts several of aluminum's neurotoxic effects.

6 Aug 2013

Isis Pharmaceuticals announces results of ISIS-CRPRx Phase 2 study in RA patients

Isis Pharmaceuticals, Inc. (NASDAQ: ISIS) announced that patients treated with ISIS-CRPRx achieved rapid, dose-dependent mean reductions of up to 67 percent in C-reactive protein (CRP) in a Phase 2 study in patients with rheumatoid arthritis (RA).

6 Aug 2013

NIH-funded study of aquaporin proteins could hold clues to cataract

Researchers have achieved dynamic, atomic-scale views of a protein needed to maintain the transparency of the lens in the human eye. The work, funded in part by the National Institutes of Health, could lead to new insights and drugs for treating cataract and a variety of other health conditions.

6 Aug 2013

Novel way to dramatically raise potency of drug candidates targeting RNA

Scientists from the Jupiter campus of The Scripps Research Institute (TSRI) have shown a novel way to dramatically raise the potency of drug candidates targeting RNA, resulting in a 2,500-fold improvement in potency and significantly increasing their potential as therapeutic agents.

6 Aug 2013

Signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy

A team of scientists, led by Napoleone Ferrara, MD, has shown for the first time that a signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy.

6 Aug 2013

Study shows how bioactive component in soy foods plays a role against colon cancer

University of Illinois scientists have evidence that lifelong exposure to genistein, a bioactive component in soy foods, protects against colon cancer by repressing a signal that leads to accelerated growth of cells, polyps, and eventually malignant tumors.

6 Aug 2013

Bayer Collaboration Could Net $540M+ For Compugen

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6 Aug 2013

Nano-machine cell killer offers new insight into fight against pathogens

This is a veritable mechanics of aggression on the nanoscale. Certain bacteria, including Staphylococcus aureus, have the ability to deploy tiny darts. This biological weapon kills the host cell by piercing the membrane.

5 Aug 2013

Disruption to TOP3B gene increases susceptibility to schizophrenia and a learning disorder

A team of researchers have shown that schizophrenia and a disorder associated with autism and learning difficulties share a common biological pathway. This is one of the first times that researchers have uncovered genetic evidence for the underlying causes of schizophrenia.

5 Aug 2013

Researchers find vital enzyme complex that gets elevated in many cancers

A team of researchers from Philadelphia and Norway has determined the structure of an enzyme complex that modifies one end of most human proteins and is made at elevated levels in numerous forms of cancer. A study in Nature Structural & Molecular Biology, led by researchers at The Wistar Institute, depicts the structure and the means of action of a protein complex called NatA.

5 Aug 2013

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

New Studies in Mice Support Toxic Role of Aluminum in Neurodegenerative Conditions, According to Report in Restorative Neurology and Neuroscience

3 Aug 2013

Boulder Brands commends FDA's gluten-free labeling standards

Boulder Brands commends the U.S. Food and Drug Administration's decision today to standardize gluten-free labeling. Glutino and Udi's, Boulder Brands' gluten-free brands and trusted pioneers and leaders in gluten-free living, have spent years advocating for the FDA to create this mandate.

3 Aug 2013

New study paves way for novel approaches to protect people from infections

A new study published by University of Utah researchers is paving the way for novel approaches related to how people are immunized to protect them from diseases.

3 Aug 2013

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

An experimental treatment for alcohol dependence works better in individuals who possess specific combinations of genes that regulate the function and binding of serotonin, a brain chemical affected by the treatment, according to a study supported by the National Institutes of Health. A report of the finding appears online in the American Journal of Psychiatry.

3 Aug 2013

Omission Brewing announces support for FDA's gluten-free labeling standard

Omission Brewing Company today announced support for the FDA's new gluten-free labeling standard as an important step forward in providing clear, consistent guidance to gluten sensitive consumers, including celiac disease sufferers. With the new labeling rules issued today, the FDA has officially adopted the widely accepted standard of 20 ppm gluten, which has been in place in many countries around the world for several years.

3 Aug 2013

New research may influence development of anti-viral therapies to fight against Dengue

New research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus.

3 Aug 2013

Protein C News and Research

Scientists discover biomarker that helps physicians predict how well cancer patients respond to drugs

Researchers identify specific genetic mutations that contribute to disorders of brain development

Combining drugs that target AXL and ErbB receptors could offer better way to fight tumors

Ensemble Therapeutics initiates research and development collaboration with Novartis

New studies in mice support toxic role of aluminum in neurodegenerative conditions

Isis Pharmaceuticals announces results of ISIS-CRPRx Phase 2 study in RA patients

NIH-funded study of aquaporin proteins could hold clues to cataract

Novel way to dramatically raise potency of drug candidates targeting RNA

Signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy

Study shows how bioactive component in soy foods plays a role against colon cancer

Bayer Collaboration Could Net $540M+ For Compugen

Nano-machine cell killer offers new insight into fight against pathogens

Disruption to TOP3B gene increases susceptibility to schizophrenia and a learning disorder

Researchers find vital enzyme complex that gets elevated in many cancers

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

Boulder Brands commends FDA's gluten-free labeling standards

New study paves way for novel approaches to protect people from infections

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

Omission Brewing announces support for FDA's gluten-free labeling standard

New research may influence development of anti-viral therapies to fight against Dengue

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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