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St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

New genetic model identified for predicting outcomes in patients with primary myelofibrosis

A group of investigators from Mayo Clinic and multiple academic research centers in Italy have identified a genetic model for predicting outcomes in patients with primary myelofibrosis who are 70 years or younger and candidates for stem cell transplant to treat their disease.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

Dengue vaccine issues in the Philippines

The Dengue virus has been difficult to control in the Philippines, and the country has been attempting to immunize its children with the new dengue vaccine Dengvaxia since January 2016.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Generic versions of Viagra coming this week

Drug manufacturer Pfizer is coming up with a cheaper and generic version of their erectile dysfunction pill Viagra this week.

10 Dec 2017

Anti-impotence drug found to be ineffective at improving outcomes for IUGR pregnancies

A University of Liverpool led international clinical trial has found an anti-impotence drug to be ineffective at improving outcomes for pregnancies complicated by fetal growth restriction.

8 Dec 2017

Modern non-invasive diagnostics can get clear picture of the heart’s condition

By no means are only elderly people at risk from heart diseases. Physically active individuals can also be affected, for example if a seemingly harmless flu bug spreads to the heart muscle. Should this remain undetected and if, for example, a builder continues with his strenuous job or an athlete carries on training, this can lead to chronic inflammation and in the worst case even to sudden death.

8 Dec 2017

Study: Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients

Although combination antiretroviral therapy (cART) has improved survival of patients infected with HIV and has reduced the incidence of severe neurologic complications, almost half of cART-treated HIV patients experience some degree of neurocognitive impairment (neuroHIV).

8 Dec 2017

Researchers develop molecular beacon to find hypoxic spots in real time

Areas of hypoxia, or low oxygen in tissue, are hallmarks of fast-growing cancers and of blockages or narrowing in blood vessels, such as stroke or peripheral artery disease. University of Illinois researchers have developed a way to find hypoxic spots noninvasively in real time.

8 Dec 2017

Nutrition labeling has little impact on sodium consumption

Potato chips, frozen pizza, a fast food hamburger- these foods are popular in the American diet and saturated with sodium. Though eating too much can lead to high blood pressure and heart disease, 90 percent of Americans eat more than the recommended amount of sodium per day.

8 Dec 2017

Researchers seek to understand role of novel protein in tumor metastasis

Metastasis, the process in which a tumor spreads to other parts of the body, is responsible for 90% of deaths from tumors. It is the greatest challenge to a cancer patient's survival. Metastatic spread occurs in several steps, these include that tumor cells become mobile and cross into and out of blood vessels.

8 Dec 2017

Simple blood test shows promise to predict risk of breast cancer relapse

A simple blood test that detects tumor cells circulating in the blood shows promise as a new way to predict high or low risk of a breast cancer relapse.

8 Dec 2017

Cities, counties and schools sidestep FDA Canadian drug crackdown, saving millions

Schenectady County, N.Y., is on track to pay 20 percent less on prescription drugs for its employees this year than in 2003.

8 Dec 2017

Gene therapy shows promising effect against blood clots, study states

A new study conducted in the Children's Hospital Of Philadelphia (CHOP) reported positive results in a phase 1/2 clinical trial for the inherited bleeding disorder hemophilia B.

8 Dec 2017

Parental lifespan genes could pave way for new therapeutic targets to prolong life

A large-scale international study led by the University of Exeter Medical School has discovered new genes linked to parents' lifespan - which could one day be targeted to help prolong human life.

8 Dec 2017

Stress in early life may raise risk of heart disease in adulthood

Stress in early life may change the immune response in the kidneys, increasing the risk of heart disease later in life, according to a new study. The paper, published ahead of print in the American Journal of Physiology- Renal Physiology, was chosen as an APSselect article for December.

7 Dec 2017

Coordinated approach in emergency care of heart attacks saves lives

Coordinating the response to heart attacks among emergency responders and hospitals reduces the time to treatment and saves lives -- even on a large, regional scale, according to a study led by the Duke Clinical Research Institute with support from the American Heart Association.

7 Dec 2017

Large-scale study expands number of genetic markers linked to exceptional longevity

A new large-scale international study expands the number of genetic markers now known to be associated with exceptional longevity.

7 Dec 2017

Blood News and Research

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

New genetic model identified for predicting outcomes in patients with primary myelofibrosis

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Dengue vaccine issues in the Philippines

Two immunotherapy approaches for multiple myeloma show hope

Generic versions of Viagra coming this week

Anti-impotence drug found to be ineffective at improving outcomes for IUGR pregnancies

Modern non-invasive diagnostics can get clear picture of the heart’s condition

Study: Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients

Researchers develop molecular beacon to find hypoxic spots in real time

Nutrition labeling has little impact on sodium consumption

Researchers seek to understand role of novel protein in tumor metastasis

Simple blood test shows promise to predict risk of breast cancer relapse

Cities, counties and schools sidestep FDA Canadian drug crackdown, saving millions

Gene therapy shows promising effect against blood clots, study states

Parental lifespan genes could pave way for new therapeutic targets to prolong life

Stress in early life may raise risk of heart disease in adulthood

Coordinated approach in emergency care of heart attacks saves lives

Large-scale study expands number of genetic markers linked to exceptional longevity

Industry Focus eBook - Cell biology (5th edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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