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Cdk5 protein may play crucial role in deadly form of thyroid cancer

A specific protein once thought to exist only in the brain may play a crucial role in a deadly form of thyroid cancer, as well as other cancers, and provide a fresh target for researchers seeking ways to stop its progression, UT Southwestern Medical Center researchers report today in Cancer Cell.

15 Oct 2013

Teva gets FDA approval for generic version of TOBI in US

Teva Pharmaceutical Industries Ltd. announces today that the U.S. Food and Drug Administration has granted approval of the generic equivalent to TOBI (Tobramycin Inhalation Solution USP) in the United States.

15 Oct 2013

Drug treatment ineffective for acute bronchitis

A study published in the BMJ indicates that neither oral antibiotics nor nonsteroidal anti-inflammatory drugs are more effective than placebo for the treatment of acute bronchitis.

14 Oct 2013

Blood pressure reduction supported for early-stage kidney disease

Blood pressure reduction per se, rather than the particular antihypertensive used, reduces the risk for cardiovascular events in patients with chronic kidney disease, shows a meta-analysis published in BMJ.

14 Oct 2013

FDA approves OTREXUP injection for adults with RA, children with active pJIA

Antares Pharma, Inc. today announced the approval of OTREXUP (methotrexate) injection by the U.S. Food and Drug Administration. OTREXUP is the first FDA approved subcutaneous methotrexate for once weekly self-administration with an easy-to-use, single dose, disposable auto injector.

14 Oct 2013

First Edition: October 14, 2013

Today's headlines include the latest on the budget negotiations as well as examinations of what's happening with the health law's online insurance marketplaces.

14 Oct 2013

Football-shaped artificial particles teach immune cells to recognize, destroy cancer cells

Researchers at Johns Hopkins have succeeded in making flattened, football-shaped artificial particles that impersonate immune cells. These football-shaped particles seem to be better than the typical basketball-shaped particles at teaching immune cells to recognize and destroy cancer cells in mice.

14 Oct 2013

BioInvent extends license agreement with Bayer to develop antibodies

BioInvent International AB today announces that it has signed an extension to its 2008 license agreement with Bayer Pharma AG for the development of antibodies from BioInvent's n-CoDeR libraries.

14 Oct 2013

Polyamine-deficient diets effective as pain relief treatment for chronic and acute pain

Before and after spinal surgery, patients on a polyamine-deficient diets experienced significant relief of both chronic and acute pain, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

14 Oct 2013

ASA launches Opioid Overdose Resuscitation card to help people who abuse prescription drugs

In response to the prescription drug abuse epidemic in the United States, the American Society of Anesthesiologists is collaborating with the White House Office of National Drug Control Policy to respond to the problem, educate the public and advance programs to help those who misuse and abuse prescription drugs.

14 Oct 2013

IV lidocaine infusion provides significant pain relief to fibromyalgia patients

Patients with fibromyalgia resistant to more routine therapies have a new pain relief treatment available, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

14 Oct 2013

Researchers create online database of disease genes that could be targeted with drugs

Researchers at Washington University School of Medicine in St. Louis have created a massive online database that matches thousands of genes linked to cancer and other diseases with drugs that target those genes.

14 Oct 2013

PARP inhibitor drugs and chemotherapy can help women with ovarian cancer live longer

Conventional chemotherapy could further extend life in some women with ovarian cancer when used in tandem with a new type of targeted treatment, a new international study shows.

13 Oct 2013

Research roundup: Medicare Part D in 2014; barriers to mental health care; scattered patterns of ACOs

Medicare Part D continues to be a marketplace with an array of competing plans offered at a wide range of premiums and benefit designs. In 2014, Medicare beneficiaries will have a choice of 35 stand-alone PDPs, on average, up by four from 2013. ... Beneficiaries receiving Low-Income Subsidies will have access to a modestly higher number of plans for no monthly premium in 2014 compared to 2013 ... Notable trends for 2014 include a growing share of PDPs using preferred pharmacy networks and adopting more formulary cost-sharing tiers.

12 Oct 2013

Scientists develop new method to regenerate cartilage

Unlike our bones, the cartilage inside our joints is not vascularized (i.e., it has no blood vessels). This is one reason why cartilage does not heal well after an injury. In athletes in particular, joint injuries often result in cartilage degeneration and arthritis. The process is chronic and irreversible, and to this day, no effective treatment exists.

12 Oct 2013

Researchers discover how Fra-1 protein protects the liver from drug-induced liver damage

Drug abuse and alcohol are some of the most frequent causes of liver damage, particularly in developed countries. Such kind of liver damage can cause irreversible liver failure and even cancer. Researchers from the Spanish National Cancer Research Centre have discovered an important new protective role of the Fra-1 protein, which neutralizes the damage caused by agents, such as the analgesic drug acetaminophen (Paracetamol).

12 Oct 2013

Sanofi's Nasacort Allergy 24HR nasal spray receives FDA approval for over-the-counter use

Sanofi announced today that the U.S. Food and Drug Administration approved Nasacort Allergy 24HR nasal spray as an over-the-counter treatment for seasonal and year-round nasal allergies in adults and children 2 years of age and older.

12 Oct 2013

Scientists introduce new approach to the production of synthetic heparin mimetics

One of the risks of any large operation is the occurrence of blood clots. To prevent this, patients are routinely given the anticoagulant heparin or related drugs. American scientists have now introduced a new approach to the production of synthetic heparin mimetics with better activity profiles.

11 Oct 2013

State highlights: Calif. gov. signs bill allowing some non-physicians to perform early abortions; audit questions facts around N.C. Medicaid managed care

Giving California women more access to abortion, Gov. Jerry Brown signed a bill Wednesday that allows nurse practitioners and certain other non-physicians to perform the procedure during the first trimester of pregnancy.

11 Oct 2013

TSRI scientists discover viable strategy for weight loss in people

Scientists at The Scripps Research Institute have discovered key details of a brain-to-body signaling circuit that enables roundworms to lose weight independently of food intake. The weight-loss circuit is activated by combined signals from the worm versions of the neurotransmitters serotonin and adrenaline, and there are reasons to suspect that it exists in a similar form in humans and other mammals.

11 Oct 2013

Drugs News and Research

Cdk5 protein may play crucial role in deadly form of thyroid cancer

Teva gets FDA approval for generic version of TOBI in US

Drug treatment ineffective for acute bronchitis

Blood pressure reduction supported for early-stage kidney disease

FDA approves OTREXUP injection for adults with RA, children with active pJIA

First Edition: October 14, 2013

Football-shaped artificial particles teach immune cells to recognize, destroy cancer cells

BioInvent extends license agreement with Bayer to develop antibodies

Polyamine-deficient diets effective as pain relief treatment for chronic and acute pain

ASA launches Opioid Overdose Resuscitation card to help people who abuse prescription drugs

IV lidocaine infusion provides significant pain relief to fibromyalgia patients

Researchers create online database of disease genes that could be targeted with drugs

PARP inhibitor drugs and chemotherapy can help women with ovarian cancer live longer

Research roundup: Medicare Part D in 2014; barriers to mental health care; scattered patterns of ACOs

Scientists develop new method to regenerate cartilage

Researchers discover how Fra-1 protein protects the liver from drug-induced liver damage

Sanofi's Nasacort Allergy 24HR nasal spray receives FDA approval for over-the-counter use

Scientists introduce new approach to the production of synthetic heparin mimetics

State highlights: Calif. gov. signs bill allowing some non-physicians to perform early abortions; audit questions facts around N.C. Medicaid managed care

TSRI scientists discover viable strategy for weight loss in people

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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