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Scientists identify new genetic mutations that can cause pulmonary arterial hypertension

Columbia University Medical Center (CUMC) scientists have identified new genetic mutations that can cause pulmonary arterial hypertension (PAH), a rare fatal disease characterized by high blood pressure in the lungs.

25 Jul 2013

Faulty genetic pathway is a potent player in many types of allergies, say researchers

Newly published research by investigators at the Johns Hopkins Children's Center and the Johns Hopkins Institute of Genetic Medicine reveals that a faulty genetic pathway already known for its role in some connective tissue disorders is also a potent player in many types of allergies.

25 Jul 2013

Athletes should eat high fiber, low-fat food to maintain muscle, says OSU researcher

Athletes seeking a healthy performance weight should eat high fiber, low-fat food balanced with their training regimen in order to maintain muscle while still burning fat, according to a report by an Oregon State University researcher.

24 Jul 2013

Researchers discover mechanism that prevents immune system from spinning out of control

A team led by a University of Arizona researcher has discovered a previously unknown mechanism that prevents the immune system from going into overdrive, shedding light not only on how our body controls its response to pathogens but on conditions such as autoimmune diseases, allergies and chronic inflammation as well.

24 Jul 2013

Bacterial crystal protein could be safe, inexpensive treatment for parasitic worms in humans

A benign crystal protein, produced naturally by bacteria and used as an organic pesticide, could be a safe, inexpensive treatment for parasitic worms in humans and provide effective relief to over a billion people around the world.

24 Jul 2013

Findings open new perspectives for research on proteins that control metastasis

In experiments on zebrafish, Freiburg researchers have demonstrated that the same proteins that lead to the formation of metastases in humans also cause the cells to migrate during embryonic development.

24 Jul 2013

Platelet activation inhibits host cell entry of HIV, shows research

Scientists of the DPZ have shown that platelet activation inhibits the host cell entry of HIV. Infection biologists of the German Primate Center (DPZ) under the direction of Stefan Pöhlmann have found evidence that platelets (thrombocytes) might constitute an innate defense against infection with the human immunodeficiency virus (HIV).

24 Jul 2013

Scientists reveal new images of how white blood immune cells attack tumours, viral infections

Scientists from The University of Manchester have revealed new images which provide the clearest picture yet of how white blood immune cells attack viral infections and tumours.

From The University of Manchester 24 Jul 2013

Astrocytes can protect brain tissue and reduce disability due to stroke

One of regenerative medicine's greatest goals is to develop new treatments for stroke. So far, stem cell research for the disease has focused on developing therapeutic neurons - the primary movers of electrical impulses in the brain - to repair tissue damaged when oxygen to the brain is limited by a blood clot or break in a vessel. New UC Davis research, however, shows that other cells may be better suited for the task.

24 Jul 2013

Research: No association between pre-natal mercury exposure and autism-like behaviors

The potential impact of exposure to low levels of mercury on the developing brain - specifically by women consuming fish during pregnancy - has long been the source of concern and some have argued that the chemical may be responsible for behavioral disorders such as autism.

24 Jul 2013

Discovery may help explain how anti-inflammatory steroid drugs work

A gene long presumed dead comes to life under the full moon of inflammation, Stanford University School of Medicine scientists have found.

23 Jul 2013

Potential breakthrough to help prevent diabetes

The resistance to insulin seen in type 2 diabetics is caused partly by the lack of a protein that has not previously been associated with diabetes. This breakthrough could potentially help to prevent diabetes.

23 Jul 2013

Melatonin pre-treatment greatly increases cell survival, say researchers

When melatonin, a hormone secreted by the pineal gland, was used as a pre-treatment for mesenchymal stem cells prior to their transplantation into the brains of laboratory animals to repair damage from stroke, researchers in China found that the stem cells survived longer after transplantation. Previous studies had shown that 80 percent of transplanted MSCs died within 72 hours of transplantation.

23 Jul 2013

Scientists identify circuitry in brain that drives compulsive drinking in rats

A research team led by scientists from the Ernest Gallo Clinic and Research Center at the University of California, San Francisco has identified circuitry in the brain that drives compulsive drinking in rats, and likely plays a similar role in humans.

23 Jul 2013

NF-κB protein complex may boost immune system to eliminate cancerous cells

Researchers at Moffitt Cancer Center and Tianjin Medical University Cancer Institute and Hospital in China have discovered a gene expression signature that may lead to new immune therapies for lung cancer patients.

23 Jul 2013

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

P53 is a tumor suppressor gene. The gene encodes for a protein that monitors the state of the cell. If something goes wrong, it stops the cell from dividing or causes the cell to commit suicide. I call it the “guardian of the genome” as it is the molecule that seems to keep cells normal. It is one of our big defenses against cancer.

22 Jul 2013

Research: Arg-Phe-amide-related peptides may be important regulators of reproductive axis

During the last decade, our understanding of this hypothalamus-pituitary-gonadal axis has quickly expanded.

22 Jul 2013

Cochlear implants restore usable hearing to deaf patients

Cochlear implants, electrical prosthetic devices that stimulate inner ear neurons of individuals who have lost their cochlear sensory cells, restore usable hearing to deaf patients. Cochlear implant electrodes are placed in the fluid-filled scala tympani of the cochlea, at a significant distance from the spiral ganglion and even from the spiral ganglion dendrites.

22 Jul 2013

CLAMP: A newly discovered protein that regulates genes

They say a good man is hard to find. Were it not for a newly discovered protein, the X chromosome of a male fruit fly could never be found by a gene-regulating complex that male flies need to develop and survive. And that case is just one example of what the new finding means. More generally, the research provides biologists with a model of how proteins that govern gene transcription find their targets on chromosomes, a process that's essential to healthy cell function and sometimes implicated in disease.

22 Jul 2013

Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

Macrophages, also known as scavenger cells, play an important role in defending against bacteria and pathogens by activating inflammatory processes. In cases of lung inflammation (pneumonia) caused by pneumococcal bacteria, this important immune response function is hampered and blocked by the protein lipocalin 2.

22 Jul 2013

Protein C News and Research

Scientists identify new genetic mutations that can cause pulmonary arterial hypertension

Faulty genetic pathway is a potent player in many types of allergies, say researchers

Athletes should eat high fiber, low-fat food to maintain muscle, says OSU researcher

Researchers discover mechanism that prevents immune system from spinning out of control

Bacterial crystal protein could be safe, inexpensive treatment for parasitic worms in humans

Findings open new perspectives for research on proteins that control metastasis

Platelet activation inhibits host cell entry of HIV, shows research

Scientists reveal new images of how white blood immune cells attack tumours, viral infections

Astrocytes can protect brain tissue and reduce disability due to stroke

Research: No association between pre-natal mercury exposure and autism-like behaviors

Discovery may help explain how anti-inflammatory steroid drugs work

Potential breakthrough to help prevent diabetes

Melatonin pre-treatment greatly increases cell survival, say researchers

Scientists identify circuitry in brain that drives compulsive drinking in rats

NF-κB protein complex may boost immune system to eliminate cancerous cells

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

Research: Arg-Phe-amide-related peptides may be important regulators of reproductive axis

Cochlear implants restore usable hearing to deaf patients

CLAMP: A newly discovered protein that regulates genes

Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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