Laboratory News and Research

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Potential new therapeutic option for prevention of PD-associated neuropathology

Scientists have identified a synergistic interaction that disrupts normal intracellular transport mechanisms and leads to the accumulation of neuron-damaging clumps of protein associated with Parkinson's disease (PD), a neurodegenerative disorder that is characterized by a specific loss of neurons in the midbrain and brainstem. The research, published by Cell Press in the December 24 issue of the journal Neuron, identifies a new potential therapeutic option for preventing PD-associated neuropathology.

24 Dec 2009

Study evaluates anemia treatment approaches adopted by different specialists

BioTrends Research Group, Inc. published a syndicated research report, "TreatmentTrends®: Anemia in the United States," based on primary research conducted with approximately 400 physicians in clinical practice.

24 Dec 2009

Researchers unveil complete genetic make-up of cavity-causing bacterium

Researchers have uncovered the complete genetic make-up of the cavity-causing bacterium Bifidobacterium dentium Bd1, revealing the genetic adaptations that allow this microorganism to live and cause decay in the human oral cavity.

24 Dec 2009

New compound may halt drug-resistant lung cancer

The ability to make, test, and map the atomic structure of new anti-cancer agents has enabled a team of Dana-Farber Cancer Institute scientists to discover a compound capable of halting a common type of drug-resistant lung cancer.

24 Dec 2009

Study: Protein channel aids nerve sensors in controlling blood pressure

University of Iowa researchers have shown that a protein channel helps nerve sensors in blood vessels keep blood pressure in check. Without the protein channel, known as ASIC2, the sensors are unable to send the brain the signals it needs to properly control blood pressure.

24 Dec 2009

Elusys Therapeutics receives contract to speed up drug development for Anthrax

The HHS Biomedical Advanced Research and Development Authority (BARDA) today awarded a contract to Elusys Therapeutics, Inc. of Pine Brook, N.J., for the advanced development of a medication to treat inhalational anthrax, one of the top bioterrorism threats facing the nation.

23 Dec 2009

Discovery enables scientists to devise novel strategies to diagnose and treat brain cancer

A team of Columbia scientists have discovered two genes that, when simultaneously activated, are responsible for the most aggressive forms of human brain cancer.

23 Dec 2009

RPC declares 2010 business plans

Radient Pharmaceuticals Corporation, a US-based vertically integrated pharmaceutical company, whose wholly-owned subsidiary AMDL Diagnostics, Inc. (ADI) announced today it 2010 Business Plan. This forecast is based upon the Company raising at least $2 million during the first half of 2010.

23 Dec 2009

Reduced calories increase human cell lifespan

Going back for a second dessert after your holiday meal might not be the best strategy for living a long, cancer-free life say researchers from the University of Alabama at Birmingham. That's because they've shown exactly how restricted calorie diets-specifically in the form of restricted glucose-help human cells live longer. This discovery, published online in The FASEB Journal (http://www.fasebj.org) could help lead to drugs and treatments that slow human aging and prevent cancer.

23 Dec 2009

Embryo biopsy safe for singleton pregnancies

The largest and longest running study of children born after preimplantation genetic diagnosis and screening has shown that embryo biopsy does not adversely affect the health of babies born as the result of a subsequent singleton pregnancy.

23 Dec 2009

NHLBI grant for identifying genetic and epigenetic causes of human congenital heart disease

Researchers at Children's Hospital Boston and Brigham and Women's Hospital have received funding from the National Heart, Lung, and Blood Institute (NHLBI) to support their search for undiscovered gene defects that cause congenital heart disease. The $4.19 million, 6-year grant is part of the Pediatric Cardiac Genomics Consortium (PCGC), which seeks to identify genetic and epigenetic causes of human congenital heart disease, and relate genetic variants present in the congenital heart disease patient population to clinical outcomes.

23 Dec 2009

MSU researchers expand global health outreach

Expanding Michigan State University's global health outreach, a team of researchers is working in the Dominican Republic to establish a model for HIV/AIDS care that can be exported to other resource-limited countries.

23 Dec 2009

U.S. Congress approves $1.6 million for AdMeTech Foundation's research program

AdMeTech Foundation, a nonprofit organization, announced today that the U.S. Congress has approved $1.6 million for funding of its groundbreaking research program aimed at developing novel imaging technologies for early prostate cancer detection, which in turn is critical for saving lives and designing customized patient care, including the most effective and the least invasive approach.

23 Dec 2009

New community-associated strain of MRSA more apt to cause serious problems

The often feared and sometimes deadly infections caused by MRSA - methicillin-resistant Staphylococcus aureus - are now moving out of hospitals and emerging as an even more virulent strain in community settings and on athletic teams, and raising new concerns about antibiotic resistance.

23 Dec 2009

Scientists develop inexpensive dipstick test to identify pesticides in foods and beverages

Scientists in Canada are reporting the development of a fast, inexpensive "dipstick" test to identify small amounts of pesticides that may exist in foods and beverages. Their paper-strip test is more practical than conventional pesticide tests, producing results in minutes rather than hours by means of an easy-to-read color-change, they say.

23 Dec 2009

Scientists explain how smallpox viruses disrupt immune systems

A team of researchers working in a high containment laboratory at the Centers for Disease Control and Prevention in Atlanta, GA, have solved a fundamental mystery about smallpox that has puzzled scientists long after the natural disease was eradicated by vaccination.: they know how it kills us.

23 Dec 2009

New drug to stop cancer cells from growing and to stimulate immune system to destroy cancer cells found

A study conducted at Scott & White Healthcare in Temple, Texas, found that a new drug stopped the growth of breast tumors in mice. This drug is unique in that it works both by stopping the cancer cells from growing and metastasizing to other organs, and by stimulating the immune system to destroy breast cancer cells and keeps them from coming back.

23 Dec 2009

WuXi PharmaTech announces winners of third Life Science and Chemistry Awards

WuXi PharmaTech, a leading pharmaceutical, biotechnology, and medical-device research and development outsourcing company with operations in China and the United States, today announced the winners of its third Life Science and Chemistry Awards, held on December 20, 2009, at the China World Hotel in Beijing.

23 Dec 2009

Guardian Technologies International meets and presents SM TBDx to Indian healthcare officials

Tuberculosis (TB) continues to be a serious global pandemic health threat with more than 9 million new cases diagnosed annually. TB is a leading cause of mortality in India, killing nearly 1,000 people each day.

23 Dec 2009

Niacin may not be beneficial for type 2 diabetic patients

High-density lipoprotein (HDL), known as "good" cholesterol, isn't as protective for people with type 2 diabetes, according to research reported in Circulation: Journal of the American Heart Association.

22 Dec 2009