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Experimental Therapeutics, Debiopharm join to develop oral small molecules targeting new class of epigenetic modulators

The Agency for Science, Technology and Research (A*STAR)'s Experimental Therapeutics Centre (ETC), a center of excellence to advance and accelerate drug discovery in Singapore, and Debiopharm Group™ (Debiopharm), the Swiss-based global biopharmaceutical company that focuses on the development of prescription drugs that target unmet medical needs including oncology as well as companion diagnostics, today announced the signature of an exclusive research collaboration to develop oral small molecules targeting new class of epigenetic modulators.

7 Oct 2013

Renowned leaders in diabetes prevention, treatment, research to descend at Jefferson Symposium

Renowned national and international leaders in diabetes prevention, treatment and research will descend on Philadelphia for the Second Annual Diabetes Symposium: New Advances and Innovations, a one-day symposium on advancing patient care at the intersection of diabetes and cardiovascular disease, cancer, sexual health and new this year, physicians and diabetes educators will address the latest advances in managing obesity in the diabetic patient.

7 Oct 2013

Newly discovered compound could be developed as antifungal drug to treat fungal infections

On a molecular level, you have more in common with shower curtain mold or the mushrooms on your pizza than you might think. Humans and fungi share similar proteins, a biological bond that makes curing fungal infections difficult and expensive.

7 Oct 2013

Anti-inflammatory mechanism leads to development of oral medications for atherosclerosis, IBS

Research led by Charles Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, describes a powerful new anti-inflammatory mechanism that could lead to the development of new oral medications for atherosclerosis and inflammatory bowel disorders (IBS).

7 Oct 2013

Researchers create catalyst that alters chemical profiles of numerous types of small molecules

Researchers report that they have created a man-made catalyst that is an "enzyme mimic." Unlike most enzymes, which act on a single target, the new catalyst can alter the chemical profiles of numerous types of small molecules.

7 Oct 2013

ERK pathway discovery may provide therapeutic options for treating drug addictions

The extracellular-signal regulated kinase (ERK) pathway plays a role in multiple drug addictions and appears to modulate neuronal plasticity through epigenetic mechanisms, say French scientists.

7 Oct 2013

Glutamergic agents may be used as novel treatment for mood and anxiety disorders

Glutamergic agents may one day be used as a novel treatment for mood and anxiety disorders, new research presented at the 26th ECNP Congress suggests.

7 Oct 2013

Self-medication is key reason for prescription drug abuse in docs

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5 Oct 2013

MIT investigators receive DARPA grant to develop new technologies for BioMOD program

Investigators from MIT's Biomanufacturing Research Program (BioMAN) have received a $10.4 million grant from the Defense Advanced Research Projects Agency (DARPA) to develop new technologies for DARPA's Biologically-derived Medicines On Demand (BioMOD) program.

5 Oct 2013

FDA approves Clinolipid injectable emulsion for intravenous feeding in adult patients

The U.S. Food and Drug Administration today approved Clinolipid (lipid injectable emulsion, USP) for intravenous feeding (parenteral nutrition) in adult patients, providing a source of calories and essential fatty acids for adult patients who are unable to eat or drink. Clinolipid was granted a priority review to help alleviate a drug shortage.

5 Oct 2013

Study shows precision medicine provides better treatment options for mentally ill person

A multidisciplinary team led by a geneticist and psychiatrist from Cold Spring Harbor Laboratory's (CSHL) Stanley Institute for Cognitive Genomics today publish a paper providing a glimpse of both the tremendous power and the current limitations of what is sometimes called "precision medicine."

5 Oct 2013

New biomarker for pancreatic cancer effectively targets potential therapy for small survival rate

University of Cincinnati (UC) researchers have discovered a biomarker, known as phosphatidylserine (PS), for pancreatic cancer that could be effectively targeted, creating a potential therapy for a condition that has a small survival rate.

5 Oct 2013

Researchers discover way to use stem cells as drug delivery vehicles

A group of Brigham and Women's Hospital, and Harvard Stem Cell Institute researchers and collaborators at MIT and MGH have found a way to use stem cells as drug delivery vehicles.

5 Oct 2013

Researchers receive prestigious European Health Award for project on new psychoactive drugs

The prestigious European Health Award 2013 has been awarded to Dr Ornella Corazza for the Recreational Drugs European Network (ReDNet), a collaborative prevention project on new psychoactive drugs led by University of Hertfordshire researchers Professor Fabrizio Schifano and Dr Corazza.

5 Oct 2013

Report: Doctors who abuse prescription drugs often do so for "self-medication"

Doctors who abuse prescription drugs often do so for "self-medication"—whether for physical or emotional pain or stress relief, reports a study in the October Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine.

5 Oct 2013

Metabolic enzymes in opium poppy are used to produce valuable painkilling drugs

University of Calgary scientists have discovered metabolic enzymes in the opium poppy that play "widespread roles" in enabling the plant to make painkilling morphine and codeine, and other important compounds.

5 Oct 2013

Modern strains of MRSA have become broadly resistant to antibiotics: Study

University of Notre Dame researchers Shahriar Mobashery and Mayland Chang and their collaborators in Spain have published research results this week that show how methicillin-resistant Staphylococcus aureus (MRSA) regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics.

5 Oct 2013

Drugs News and Research

Experimental Therapeutics, Debiopharm join to develop oral small molecules targeting new class of epigenetic modulators

Renowned leaders in diabetes prevention, treatment, research to descend at Jefferson Symposium

Newly discovered compound could be developed as antifungal drug to treat fungal infections

Anti-inflammatory mechanism leads to development of oral medications for atherosclerosis, IBS

Researchers create catalyst that alters chemical profiles of numerous types of small molecules

ERK pathway discovery may provide therapeutic options for treating drug addictions

Glutamergic agents may be used as novel treatment for mood and anxiety disorders

Self-medication is key reason for prescription drug abuse in docs

MIT investigators receive DARPA grant to develop new technologies for BioMOD program

FDA approves Clinolipid injectable emulsion for intravenous feeding in adult patients

Study shows precision medicine provides better treatment options for mentally ill person

New biomarker for pancreatic cancer effectively targets potential therapy for small survival rate

Researchers discover way to use stem cells as drug delivery vehicles

Researchers receive prestigious European Health Award for project on new psychoactive drugs

Report: Doctors who abuse prescription drugs often do so for "self-medication"

Metabolic enzymes in opium poppy are used to produce valuable painkilling drugs

Modern strains of MRSA have become broadly resistant to antibiotics: Study

New technique for breast cancer treatment and prevention-injection via nipple

New therapeutic targets and drugs may benefit people with leukemia

Scientists identify chemical agents that block flu virus's ability to replicate itself in cell culture

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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