Protein C News and Research

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Study identifies new therapeutic targets for Huntington's disease

A scientific study describes that GluN3A subunits of NMDA receptors that interact with glutamate —the main exciting neurotransmitter in the nervous system— are therapeutic targets against Huntington's disease.

16 Jul 2013

Pair of studies sheds light on cancer cell signaling

A pair of studies by a team of University of Notre Dame researchers led by Crislyn D'Souza-Schorey, professor of biological sciences, sheds light on a biological process which is activated across a vast range of malignancies.

16 Jul 2013

Law of physics can be demonstrated by collection of individual protein molecules

Experiments by biochemists at the University of California, Davis show for the first time that a law of physics, the ergodic theorem, can be demonstrated by a collection of individual protein molecules -- specifically, a protein that unwinds DNA. The work will be published online by the journal Nature on July 14.

16 Jul 2013

New application note describes ChIP assay technology for screening multiple epigenetic targets

Porvair Sciences has announced an application note describing the excellent results achievable from a new 96-well format version of its ChromaTrap chromatin immunoprecipitation assay technology.

From Chromatrap® - Porvair Sciences Ltd 16 Jul 2013

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

As surgeons who take care of cancer patients, we have observed a troubling association between patients who suffer from infections after surgery and the rapid spread of their cancer. We have reported this in lung cancer patients, and others have made these observations in a variety of different cancers. However, the mechanisms responsible for this association are still poorly understood.

16 Jul 2013

USC study shows missing brain protein may be responsible for severe over-worry and fear

A little bit of learned fear is a good thing, keeping us from making risky, stupid decisions or falling over and over again into the same trap. But new research from neuroscientists and molecular biologists at USC shows that a missing brain protein may be the culprit in cases of severe over-worry, where the fear perseveres even when there's nothing of which to be afraid.

16 Jul 2013

Protein complex may be an effective alternative to opioid pain medications

A drug targeting a protein complex containing two different types of opioid receptors may be an effective alternative to morphine and other opioid pain medications, without any of the side effects or risk of dependence, according to research led by the Icahn School of Medicine at Mount Sinai.

16 Jul 2013

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced it has received approval by the U.S. Food and Drug Administration (FDA) to market the therascreen EGFR test as a companion diagnostic to guide the use of Boehringer Ingelheim's new targeted therapy, GILOTRIF™ (afatinib), for treatment of metastatic NSCLC in patients whose tumors have certain EGFR gene mutations.

From QIAGEN Manchester Limited 15 Jul 2013

Scientists discover new details of biochemical interactions necessary for cell division

Building on earlier work exploring the complex choreography by which intricate cellular proteins interact with and copy DNA prior to cell division, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators have captured a key step-molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target.

15 Jul 2013

Scientists uncover mechanism that controls cell death processes

Scientists have uncovered the mechanism that controls whether cells that are able to suppress immune responses live or die.

15 Jul 2013

Scientists discover novel method to kill cancer cells

A University of Southampton Professor, in collaboration with colleagues at the BC Cancer Agency Research Centre, have discovered a novel way of killing cancer cells. The research, recently published in the journal Cell, has found a new potential treatment for cancer, which leaves the body's healthy cells undamaged, unlike traditional therapies such as radiotherapy

15 Jul 2013

Natural tissue graft can spur regeneration of cartilage; improves symptoms in knee cartilage damaged patients

A natural tissue graft can spur regeneration of cartilage and improve symptoms in patients who have cartilage damage in their knee, according to a study by researchers from Hospital for Special Surgery.

15 Jul 2013

New discovery reveals how RNA moves genetic information from DNA to create proteins

The discovery cracks the "RNA control code," which dictates how RNA - a family of molecules that mediates DNA expression - moves genetic information from DNA to create proteins.

15 Jul 2013

RXi Pharmaceuticals reports positive results from second Phase 1 study with RXI‑109

RXi Pharmaceuticals Corporation, a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced positive results from their second placebo-controlled Phase 1 study with RXI‑109, an sd-rxRNA compound that targets Connective Tissue Growth Factor, and is being developed for the treatment of abnormal dermal scars such as hypertrophic scars and keloids in conjunction with scar revision surgery.

12 Jul 2013

Healthcare system factors may play a role in racial disparities related to kidney failure

Among patients with kidney disease who received specialized pre-dialysis care in a universal healthcare system, blacks experienced faster disease progression than whites, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The findings suggest that healthcare system factors have less influence on black-white disparities in kidney function decline than other factors.

12 Jul 2013

Researchers find new potential treatment for cancer

12 Jul 2013

UC Riverside professor receives grant to study potential treatment for age-related macular degeneration

A University of California, Riverside bioengineering professor has received a two-year, $120,000 grant to search for chemical compounds that have the potential to treat age-related macular degeneration.

12 Jul 2013

Research: Experimental drug can protect kidneys from acute kidney injury

New research reveals the mechanism by which an experimental drug can protect the kidneys from sudden damage, called acute kidney injury (AKI). The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), show how the drug may be able to save many lives and cut medical costs related to the condition.

12 Jul 2013

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive top-line results from its ongoing Phase I trial of ALN-TTRsc, a subcutaneously administered RNAi therapeutic targeting the transthyretin gene for the treatment of TTR-mediated amyloidosis.

12 Jul 2013

Protein that triggers blood clotting plays critical role in growth of pancreatic and breast cancer

A recently discovered form of the protein that triggers blood clotting plays a critical role in promoting the growth of metastatic pancreatic cancer and primary breast cancer, according to the cumulative findings from two new scientific manuscripts published online ahead of print in the International Journal of Cancer and PNAS (Proceedings of the National Academy of Sciences).

12 Jul 2013

Protein C News and Research

Study identifies new therapeutic targets for Huntington's disease

Pair of studies sheds light on cancer cell signaling

Law of physics can be demonstrated by collection of individual protein molecules

New application note describes ChIP assay technology for screening multiple epigenetic targets

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

USC study shows missing brain protein may be responsible for severe over-worry and fear

Protein complex may be an effective alternative to opioid pain medications

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

Scientists discover new details of biochemical interactions necessary for cell division

Scientists uncover mechanism that controls cell death processes

Scientists discover novel method to kill cancer cells

Natural tissue graft can spur regeneration of cartilage; improves symptoms in knee cartilage damaged patients

New discovery reveals how RNA moves genetic information from DNA to create proteins

RXi Pharmaceuticals reports positive results from second Phase 1 study with RXI‑109

Healthcare system factors may play a role in racial disparities related to kidney failure

Researchers find new potential treatment for cancer

UC Riverside professor receives grant to study potential treatment for age-related macular degeneration

Research: Experimental drug can protect kidneys from acute kidney injury

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Protein that triggers blood clotting plays critical role in growth of pancreatic and breast cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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