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Cholesterol-lowering drugs could be alternative treatment for people who take statins

A new class of cholesterol-lowering drugs that target a recently discovered regulator of harmful cholesterol could be an alternative or complementary treatment for the 30 million people who take statins, after the first trial in humans confirms the technique’s feasibility and safety.

4 Oct 2013

Men who believe in God less likely to take drugs than atheists

Young Swiss men who say that they believe in God are less likely to smoke cigarettes or pot or take ecstasy pills than Swiss men of the same age group who describe themselves as atheists. Belief is a protective factor against addictive behaviour. This is the conclusion reached by a study funded by the Swiss National Science Foundation.

4 Oct 2013

FDA report reveals personal, professional devastation caused by cognitive dysfunctions of ME/CFS

PANDORA Org and other patient organizations say a recent report from the U.S. Food and Drug Administration (FDA) shows the agency must take further action to open up opportunities for ME/CFS drug development.

4 Oct 2013

ISIS conducts phase 2 study of ISIS-SMNRx in infants with type I spinal muscular atrophy

Isis Pharmaceuticals, Inc. (NASDAQ: ISIS) announced today that it dosed the first infant in the 12 mg dose group in the Phase 2 study evaluating ISIS-SMNRx in infants with Type I spinal muscular atrophy (SMA).

4 Oct 2013

Whitehead Institute researchers redefine gene mutation that cause Rett syndrome

Whitehead Institute researchers have redefined the function of a gene whose mutation causes Rett syndrome, a neurodevelopmental autism spectrum disorder. This new research offers an improved understanding of the defects found in the neurons of Rett syndrome patients and could lead to novel therapies for the disease.

4 Oct 2013

NYU researchers receive $6.25M grant for pioneering research into acute lymphoblastic leukemia

Researchers at The Cancer Institute at NYU Langone Medical Center is leading a $6.25 million, five-year research initiative, funded by the Leukemia & Lymphoma Society, to develop new therapies and advance the cure rate for children and young adults with acute lymphoblastic cancer (ALL), the most common form of childhood cancer.

4 Oct 2013

Parkinsonism predicts schizophrenia cognitive course

Parkinsonism is common in patients with first-episode psychosis and is predictive of cognitive impairment, say researchers.

3 Oct 2013

Discovery paves way for development of new medicines to combat herpes infections

Researchers at Lund University in Sweden and Carnegie Mellon University have for the first time managed to measure the internal pressure that enables the herpes virus to infect cells in the human body. The discovery paves the way for the development of new medicines to combat viral infections. The results indicate good chances to stop herpes infections in the future.

3 Oct 2013

Study: One in three teens with bipolar disorder develop substance abuse

A study published in the October 2013 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that approximately one in three teens with bipolar disorder developed substance abuse, for the first time, during 4 years of follow-up.

3 Oct 2013

New method to monitor activity of gene promoters during response to drug

When developing new drugs, monitoring cellular responses to candidate compounds is essential for assessing their efficacy and safety. Researchers from the RIKEN Center for Life Science Technologies report a new method to monitor and quantify the activity of gene promoters during the response to a drug, using the advanced gene expression analysis method CAGE followed by single-molecule sequencing.

3 Oct 2013

Cambridge Consultants helps MSF’s efforts to widen access to HIV viral load tests

Cambridge Consultants is working with Médecins Sans Frontières (MSF) to help support moves to expand access to vital diagnostic tests, which paves the way for better treatment of HIV in some of the world’s least-developed countries.

3 Oct 2013

Component of grape, citrus fruits block formation of kidney cysts

A new study published today in British Journal of Pharmacology has identified that a component of grapefruit and other citrus fruits, naringenin, successfully blocks the formation of kidney cysts.

3 Oct 2013

Specialized cells play major role in inflammation that underlies Crohn's disease in small intestine

Scientists have discovered that Crohn's disease, the inflammatory bowel disorder, can originate from specialised intestinal cell type called Paneth cells. As such, they propose that small intestinal Crohn's disease might be a specific disorder of this cell type, providing a possible new target for treatments.

3 Oct 2013

NCI explores how erectile dysfunction drugs work to prevent colon cancer

Erectile dysfunction drugs may be able to help prevent or even treat colon cancer, researchers say.

3 Oct 2013

UCLA study shows how cocaine makes immune cells susceptible to HIV

In many ways, the spread of HIV has been fueled by substance abuse. Shared needles and drug users' high-risk sexual behaviors are just some of the ways that narcotics such as cocaine have played a key role in the AIDS epidemic in much of the world.

3 Oct 2013

Adamas Pharmaceuticals reports positive results from ADS-5102 Phase 2/3 EASED clinical trial

Adamas Pharmaceuticals, Inc. presented positive results today from the Phase 2/3 EASED clinical trial of ADS-5102 at the World Parkinson's Congress. ADS-5102 is Adamas' proprietary long-acting capsule formulation of amantadine HCl in development for the treatment of levodopa-induced dyskinesia in Parkinson's disease patients.

2 Oct 2013

Data analyses from Brisdelle Phase 3 pivotal trials to be showcased at NAMS' meeting

Noven Pharmaceuticals, Inc., today announced that 11 presentations, featuring data analyses from its Phase 3 pivotal trials that supported the recent U.S. Food and Drug Administration approval of Brisdelle (paroxetine capsules, 7.5 mg/day) for the treatment of moderate to severe vasomotor symptoms associated with menopause, will be showcased at the 2013 Annual Meeting of The North American Menopause Society in Dallas on Oct. 9-10.

2 Oct 2013

Drugs News and Research

Cholesterol-lowering drugs could be alternative treatment for people who take statins

Men who believe in God less likely to take drugs than atheists

FDA report reveals personal, professional devastation caused by cognitive dysfunctions of ME/CFS

ISIS conducts phase 2 study of ISIS-SMNRx in infants with type I spinal muscular atrophy

Whitehead Institute researchers redefine gene mutation that cause Rett syndrome

NYU researchers receive $6.25M grant for pioneering research into acute lymphoblastic leukemia

Parkinsonism predicts schizophrenia cognitive course

Discovery paves way for development of new medicines to combat herpes infections

Study: One in three teens with bipolar disorder develop substance abuse

New method to monitor activity of gene promoters during response to drug

Cambridge Consultants helps MSF’s efforts to widen access to HIV viral load tests

Component of grape, citrus fruits block formation of kidney cysts

Specialized cells play major role in inflammation that underlies Crohn's disease in small intestine

NCI explores how erectile dysfunction drugs work to prevent colon cancer

UCLA study shows how cocaine makes immune cells susceptible to HIV

Adamas Pharmaceuticals reports positive results from ADS-5102 Phase 2/3 EASED clinical trial

Data analyses from Brisdelle Phase 3 pivotal trials to be showcased at NAMS' meeting

Hypertension Drug May Aid Cancer Treatment

NIMH Awards Optivia $1.8M CNS Drug Development

Laboratory testing kit that estimates risk of breast cancer relapse gets FDA approval

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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