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Phase II trial results of OHR/AVR118 in patients with cancer cachexia announced

Ohr Pharmaceutical, a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, today announced the results of a Phase II trial to evaluate the effects of OHR/AVR118 in advanced cancer patients with cachexia. Cancer cachexia is the complex, multi-symptom syndrome seen in late-stage cancer patients, characterized by anorexia and unintended loss of appetite, progressive and continual weight loss, accompanied by generalized host tissue wasting, skeletal muscle atrophy, immune and metabolic dysfunction, and a greatly diminished quality of life.

21 Mar 2013

Investigators examine effectiveness of probiotics for cancer treatment

One may not think of probiotics -- like those found in yogurt that promote good digestive health -- as a weapon used in the fight against cancer. But that is the focus of investigators at The Cancer Institute of New Jersey, who are examining the effectiveness of probiotics as they relate to the outcomes of bone marrow transplant for patients with blood cancers.

21 Mar 2013

New research may help clinicians determine factors that increase risk of blood clots after surgery

New research from the UC Davis Comprehensive Cancer Center, published in the Journal of Surgical Research, may help clinicians determine which patients are at highest risk for post-surgical blood clots in the legs or lungs.

21 Mar 2013

Genetically modified tomatoes mimic actions of good cholesterol

UCLA researchers have genetically engineered tomatoes to produce a peptide that mimics the actions of good cholesterol when consumed.

20 Mar 2013

Special issue on colorectal cancer published in GIE: Gastrointestinal Endoscopy journal

In recognition of National Colorectal Cancer Awareness Month, GIE: Gastrointestinal Endoscopy has published a special issue for March on colorectal cancer.

20 Mar 2013

Oral Cancer Foundation encourages dental practices to offer free oral cancer screenings in April

What has the greatest impact on survival rates of oral cancer? Radiation? Chemotherapy? Perhaps surgery? The truth is none of these; rather, it is the point in time at which the disease is discovered.

18 Mar 2013

Advanced gene sequencing test helps clinicians treat cancer

The University of Washington and Seattle Cancer Care Alliance (SCCA) partnered to launch UW-OncoPlex - an advanced gene sequencing test to help clinicians treat cancer. The new diagnostic tool is a significant milestone in the development of precision medicine and empowers doctors to predict which treatment therapies will be most effective for an individual patient's cancer.

14 Mar 2013

New study shows older patients get unnecessary colonoscopy screening

Colonoscopy is one of the most effective cancer screening procedures available. Colon cancer grows very slowly and can be treated if caught early through screening. But, perhaps because of this success, older Americans are undergoing screening colonoscopies despite recommendations against screening in adults aged 76 and older.

14 Mar 2013

Maintaining high-quality CT colonography while reducing radiation dose is possible, finds study

A new study by a Rhode Island Hospital researcher has found it's possible to maintain high-quality CT colonography diagnostic images while reducing the radiation dose.

13 Mar 2013

NCI-sponsored study to evaluate rosuvastatin for prevention of colon cancer

With March designated as Colorectal Cancer Awareness Month, the North Shore-LIJ Cancer Institute is enrolling people who were recently treated for colon cancer in a polyp prevention study. This National Cancer Institute (NCI)-sponsored study evaluates the cholesterol drug, rosuvastatin (Crestor), as a treatment to reduce the risk of colon cancer.

11 Mar 2013

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Takeda Pharmaceutical Company Limited (“Takeda”) today announced that a Marketing Authorisation Application (MAA) has been submitted to The European Medicines Agency (EMA) for vedolizumab, an investigational, gut-selective humanized monoclonal antibody for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn’s disease (CD), the two most common types of inflammatory bowel disease (IBD).

8 Mar 2013

Researchers explore genetic testing to identify people at high risk for preventable disease

In ten years time, routine preventive health care for adults may include genetic testing alongside the now familiar tests for cholesterol levels, mammography and colonoscopy.

8 Mar 2013

Visceral fat directly linked to increased risk for colon cancer, study reveals

Visceral fat, or fat stored deep in the abdominal cavity, is directly linked to an increased risk for colon cancer, according to data from a mouse study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

6 Mar 2013

Screening healthy adults could potentially prevent rare genetic disorders

Millions of people unknowingly carry rare gene mutations that put them at high risk of developing preventable diseases such as colorectal cancer, breast cancer, and several catastrophic blood vessel disorders.

6 Mar 2013

Ten tips to reduce risk of colorectal cancer

With colorectal cancer the second leading cause of cancer death, it's a great time to take a look at the health of your colon. "Colorectal cancer surpasses breast and prostate cancers as a leading cause of cancer death in men and women," said Dr. James Yoo, assistant professor of surgery and chief of the colon & rectal surgery program at the David Geffen School of Medicine at UCLA. "It is largely preventable with early screening and detection."

5 Mar 2013

Screening colonoscopy associated with reduced advanced colorectal cancer diagnoses

A new study led by a researcher at the Perelman School of Medicine at the University of Pennsylvania adds support to current medical recommendations stating that screening colonoscopy substantially reduces an average-risk adult's likelihood of being diagnosed with advanced colorectal cancer (CRC) in either the right or left side of the colon.

4 Mar 2013

Electronic health records increase colorectal cancer screening rates

Researchers used electronic health records to identify Group Health patients who weren't screened regularly for cancer of the colon and rectum-and to encourage them to be screened. This centralized, automated approach doubled these patients' rates of on-time screening-and saved health costs-over two years.

4 Mar 2013

Colonoscopy is also safe, confirms German Cancer Research Center study

Colon cancer develops slowly. Precancerous lesions usually need many years to turn into a dangerous carcinoma. They are well detectable in an endoscopic examination of the colon called colonoscopy and can be removed during the same examination. Therefore, regular screening can prevent colon cancer much better than other types of cancer.

3 Mar 2013

Weekend reading: Navigating treatment; Can a robot replace your doctor?

Your pathology report indicates that you have stomach cancer. Hearing those words conveying yet another cancer-related diagnosis - my fourth since the age of 20 - I felt, at the age of 57, as though I had been airdropped into a foreign country.

1 Mar 2013

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

According to a recent University of Eastern Finland (UEF) study, elevated cell sugar concentrations increase the production of hyaluronan which, in turn, promotes cancer growth. Regulating the production of hyaluronan may be a way to prevent the spreading of cancer.

28 Feb 2013

Colon News and Research

Phase II trial results of OHR/AVR118 in patients with cancer cachexia announced

Investigators examine effectiveness of probiotics for cancer treatment

New research may help clinicians determine factors that increase risk of blood clots after surgery

Genetically modified tomatoes mimic actions of good cholesterol

Special issue on colorectal cancer published in GIE: Gastrointestinal Endoscopy journal

Oral Cancer Foundation encourages dental practices to offer free oral cancer screenings in April

Advanced gene sequencing test helps clinicians treat cancer

New study shows older patients get unnecessary colonoscopy screening

Maintaining high-quality CT colonography while reducing radiation dose is possible, finds study

NCI-sponsored study to evaluate rosuvastatin for prevention of colon cancer

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Researchers explore genetic testing to identify people at high risk for preventable disease

Visceral fat directly linked to increased risk for colon cancer, study reveals

Screening healthy adults could potentially prevent rare genetic disorders

Ten tips to reduce risk of colorectal cancer

Screening colonoscopy associated with reduced advanced colorectal cancer diagnoses

Electronic health records increase colorectal cancer screening rates

Colonoscopy is also safe, confirms German Cancer Research Center study

Weekend reading: Navigating treatment; Can a robot replace your doctor?

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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