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Celldex commences dosing patients in Phase 1/2 study of its CDX-1401 vaccine candidate

Celldex Therapeutics, Inc. (NASDAQ: CLDX) today announced that the first patient has been dosed in a Phase 1/2 study of its vaccine candidate, CDX-1401, in patients with malignant solid tumors that express NY-ESO-1. CDX-1401 is a fully human monoclonal antibody designed to selectively deliver the NY-ESO-1 antigen to dendritic cells to generate a robust immune response against cancer cells expressing NY-ESO-1.

14 Sep 2009

Early vaccination minimizes the risk of damage by potentially harmful infections

Parents should not be worried, that early vaccination would overwhelm their babies. Recent data show, that the immune system of newborns is able to respond to a world full of antigens already at birth.

14 Sep 2009

Prevention and treatment of pneumonia are critical to reducing child mortality

New World Health Organization data to be published in this week's edition of the Lancet will shed new light on two leading causes of pneumonia, the world's leading killer of children under age 5, both globally and within specific countries.

14 Sep 2009

NIAID conducts human clinical trials of 2009 H1N1 influenza vaccines

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, also is conducting clinical trials of 2009 H1N1 influenza vaccines, produced by Sanofi Pasteur and CSL Limited. The NIAID trials are testing two different dosages (15 micrograms versus 30 micrograms) and evaluating the immune response to one and two doses of these vaccines.

14 Sep 2009

U.S., Australian researchers say single H1N1 vaccine dose protects adults against virus

The results of clinical trials have shown one dose of the H1N1 (swine) flu vaccine is enough to offer adults protection against the virus, U.S. and Australian researchers said Thursday, the Associated Press reports (Neergaard, 9/11).

11 Sep 2009

Pneumonia-causing diseases kill 1.2m children under 5 annually, Studies say

"Each year 1.2 million children under age 5 die from Streptococcus pneumoniae and Haemophilus influenzae B or Hib," which cause pneumococcal disease and are preventable with vaccines, according to studies published Thursday in the journal Lancet, Reuters reports.

11 Sep 2009

Flu Clinic Locator makes it easy for people to locate the most convenient clinic to get their seasonal flu vaccine

The American Lung Association is making it easier for people to get their seasonal flu vaccine this year with the availability of its 2009-2010 Flu Clinic Locator. The largest online directory of public seasonal influenza vaccination clinics is now available at www.flucliniclocator.org.

11 Sep 2009

HHS, Ad Council and Warner Bros unite to address childhood obesity

The U.S. Department of Health and Human Services (HHS) and the Ad Council today launched a new series of public service advertisements (PSAs) designed to address childhood overweight and obesity.

11 Sep 2009

New World Health Organization data emphasizes on two leading causes of pneumonia

New World Health Organization data to be published in this week's edition of The Lancet will shed new light on two leading causes of pneumonia, the world’s leading killer of children under age 5, both globally and within specific countries.

11 Sep 2009

Improving childhood immunization campaigns could reduce sickle-cell deaths in Africa, Study finds

By offering all children in Africa vaccines that protect against bacterial infections, researchers say the number of deaths among children living with sickle-cell anemia could be reduced, Reuters reports. An estimated 200,000 children in Africa annually are born with sickle-cell anemia, a genetic disease "in which red blood cells deform into a sickle shape and cluster, blocking blood flow and causing pain, vulnerability to infections and organ damage."

10 Sep 2009

Analysis: Marketing research sheds light low vaccination rates in some developing countries

Despite progress in raising the vaccination rates in the world's poorest countries, some countries, including the Democratic Republic of Congo, Ethiopia, India, Indonesia and Nigeria continue to have vaccination rates "below 50% in certain regions, compared with the 80% or more needed to achieve a low risk of the disease spreading," Douglas Holt, Oxford University professor of marketing, and Jacob McKnight, also of Oxford University, write in a Livemint.com analysis piece.

10 Sep 2009

U.S. public health officials recommend early flu vaccination

With increased influenza activity anticipated this fall, U.S. public health officials and other leading medical experts today urged Americans to be vigilant and get immunized early for protection against seasonal influenza - a threat to Americans' health each and every year.

10 Sep 2009

arGEN-X BV announces first closing of its Series A equity financing round

arGEN-X BV, a biopharmaceutical company focused on the discovery and development of human antibodies using its proprietary SIMPLE Antibody platform, today announced the successful first closing of its Series A equity financing round. The Company raised EUR 9.5million (~ USD 13.6 million) from a syndicate of leading life science investors. The financing round is one of the largest of its kind in the last 12 months.

10 Sep 2009

Polio vaccination resumes in Pakistan's Swat Valley

"Authorities in Pakistan's Swat Valley have resumed vaccinating children for polio, an act once banned by Taliban militants, now beaten back by an army offensive," the Associated Press reports. The three-day campaign, which started on Monday, is targeting about 215,000 children, said government official Khurshid Khan.

10 Sep 2009

WHO's Chan says swine flu will 'test' world on 'fairness'

Addressing a meeting of South East Asian health ministers Tuesday, WHO Director-General Margaret Chan said the H1N1 (swine) flu pandemic will "test the world on the issue of fairness" and "reveal in a measurable and tragic way the consequences of decades of failure to invest adequately in basic health systems and infrastructure,"

10 Sep 2009

Roche Group and ImmunoCellular Therapeutics sign research agreement regarding ICT-69 antibody

ImmunoCellular Therapeutics, Ltd. (OTCBB: IMUC), a clinical-stage biotechnology company that is developing immune based therapies for the treatment of brain and other cancers, announced today that it has entered into a research and license option agreement regarding its ICT-69 antibody with Roche Group (SWX: ROG.VX; RO.S, OTCQX: RHHBY), one of the world’s leading research-focused healthcare groups in the fields of pharmaceuticals and diagnostics.

10 Sep 2009

E.V-Trax Employee Vaccination Tracking System helps eliminate manual data entry

General Data Company, Inc., which specializes in barcode-based error-proofing and tracking system solutions, is offering a new mobile application to help healthcare organizations administer employee vaccinations and track the immunization status of their personnel for H1N1, influenza, and other vaccinations.

10 Sep 2009

First trial of 2009 H1N1 influenza vaccine testing launched

The first trial testing a candidate 2009 H1N1 influenza vaccine in pregnant women is launching this week, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, announced today.

10 Sep 2009

Merck's GARDASIL receives approval from FDA Advisory Committee

Merck & Co., Inc. announced today that the U.S. Food and Drug Administration’s (FDA) Vaccines and Related Biological Products Advisory Committee agreed that efficacy, immunogenicity and safety data from clinical trials in males support the use of GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16 and 18) Vaccine, Recombinant] in boys and men 9 through 26 years of age for the prevention of genital warts caused by human papillomavirus (HPV) types 6 and 11.

10 Sep 2009

Maxim Health to launch its annual influenza vaccination program on October 1

It is the start of the flu season and with seasonal influenza responsible for more than 36,000 deaths per year, getting a flu vaccine is critical. Today, Maxim Health Systems announced on October 1 it will launch its annual influenza vaccination program and will provide flu shots nationwide through more than 44,000 clinics.

9 Sep 2009

Immunization News and Research

Celldex commences dosing patients in Phase 1/2 study of its CDX-1401 vaccine candidate

Early vaccination minimizes the risk of damage by potentially harmful infections

Prevention and treatment of pneumonia are critical to reducing child mortality

NIAID conducts human clinical trials of 2009 H1N1 influenza vaccines

U.S., Australian researchers say single H1N1 vaccine dose protects adults against virus

Pneumonia-causing diseases kill 1.2m children under 5 annually, Studies say

Flu Clinic Locator makes it easy for people to locate the most convenient clinic to get their seasonal flu vaccine

HHS, Ad Council and Warner Bros unite to address childhood obesity

New World Health Organization data emphasizes on two leading causes of pneumonia

Improving childhood immunization campaigns could reduce sickle-cell deaths in Africa, Study finds

Analysis: Marketing research sheds light low vaccination rates in some developing countries

U.S. public health officials recommend early flu vaccination

arGEN-X BV announces first closing of its Series A equity financing round

Polio vaccination resumes in Pakistan's Swat Valley

WHO's Chan says swine flu will 'test' world on 'fairness'

Roche Group and ImmunoCellular Therapeutics sign research agreement regarding ICT-69 antibody

E.V-Trax Employee Vaccination Tracking System helps eliminate manual data entry

First trial of 2009 H1N1 influenza vaccine testing launched

Merck's GARDASIL receives approval from FDA Advisory Committee

Maxim Health to launch its annual influenza vaccination program on October 1

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