Malignant News and Research

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Protein helps leukemia cells avoid effects of chemotherapy by appearing dormant

A new study on how the progression of acute lymphocytic leukemia is influenced by the bone marrow environment has demonstrated for the first time that targeting a specialized protein known as osteopontin may be an effective strategy to increase the efficacy of chemotherapy in patients with this type of blood cancer.

16 Apr 2013

John Theurer Cancer Center to host Women's Oncology Conference for gynecologists, generalists

John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 cancer centers, will be hosting a Women's Oncology Conference for gynecologists and generalists on Wednesday, April 24 from 7:30am to 1:00 pm.

15 Apr 2013

Study: Certain types of papilloma virus might prevent cervical cancer

There are over 100 different types of human papilloma virus (HPV). Cervical cancer is known to be caused by infection with approximately 14 so-called "high-risk" types of this virus.

From The University of Manchester 12 Apr 2013

Conference on Malignant Hyperthermia to be held in Orlando

Learn the basics on how recognize, diagnose, and treat Malignant Hyperthermia by attending at the "MH Let's Save a Life" conference where patients sit side by side with healthcare professionals, students, and families learning about MH from experts affiliated with MHAUS on June 8, 2013 from 10 am - 4 pm at Orlando Regional Medical Center located in Orlando, FL.

11 Apr 2013

DelMar Pharmaceuticals reports positive results from VAL-083 Phase I/II clinical trial in patients with GBM

DelMar Pharmaceuticals, Inc. today announced additional positive interim data from an ongoing Phase I/II clinical trial of VAL-083 in patients with recurrent glioblastoma multiforme (GBM) or progressive secondary brain tumor.

11 Apr 2013

BRAF genetic mutation increases mortality among patients with papillary thyroid cancer

Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer (PTC); however, because overall mortality in PTC is low and the association was not independent of tumor characteristics, how to use this information to manage mortality risk in patients with PTC is unclear, according to a study in the April 10 issue of JAMA, a Genomics theme issue.

10 Apr 2013

First combination treatment of microwave ablation, radiotherapy performed on 52-year-old patient

Dr. Hudayi Korkusuz, a radiologist at the Department of Nuclear Medicine, has conducted the first combination treatment of microwave ablation and radiotherapy.

10 Apr 2013

New immunotherapies are seldom developed for childhood cancer

More often than not, cancer immunotherapies that work in adults are used in modified ways in children. Seldom are new therapies developed just for children, primarily because of the small number of pediatric patients relative to the adult cancer patient population.

9 Apr 2013

Researchers design drug to block incidence of head, neck cancer caused by HPV virus

Researchers have discovered a new mechanism by which the human papilloma virus (HPV) causes head and neck cancer, and they have designed a drug to block that mechanism. Though further research is needed, the new agent might offer a safer treatment for these tumors when combined with a tapered dose of standard chemotherapy.

9 Apr 2013

Researchers explore how blocking EGFR changes signaling in glioblastoma cells

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor, fuels a wide variety of cancers-including a highly malignant brain cancer known as glioblastoma.

9 Apr 2013

Certain brain tumors develop drug resistance by exploiting normal cellular signaling pathways

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors.

9 Apr 2013

Study evaluates efficacy of drug combinations in treating colorectal cancer

Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Once colorectal cancer has spread to other parts of the body, only 11 percent of patients will survive five years from the date of their diagnosis.

8 Apr 2013

Physician-researcher to lead pediatric Dream Team to create new treatments for childhood cancers

A physician-researcher from The Children's Hospital of Philadelphia will lead the first-ever pediatric "Dream Team" solely focused on creating new treatments for the most challenging childhood cancers.

8 Apr 2013

A*STAR's professor receives Szent-Gy-rgyi prize for groundbreaking cancer pill

Professor Alex Matter, Chief Executive Officer of A*STAR's Experimental Therapeutics Centre (ETC), has been awarded the 8th Annual Szent-Gy-rgyi Prize for Progress in Cancer Research by the National Foundation for Cancer Research (NFCR) for his contributions to the development of the first drug specifically targeting a molecular lesion in cancer.

7 Apr 2013

NeuroBlate Thermal Therapy System safe for treating recurrent glioblastoma, study shows

The first-in-human study of the NeuroBlate Thermal Therapy System finds that it appears to provide a new, safe and minimally invasive procedure for treating recurrent glioblastoma, a malignant type of brain tumor.

6 Apr 2013

Overexpression of miR-155 promotes growth of blood vessels in tumors and metastasis

Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in tumors, tumor inflammation, and metastasis.

4 Apr 2013

Three institutions partner to create research breakthroughs in children's health

Virginia Tech, Children's National Medical Center, and the George Washington University have partnered in a unique program to create research breakthroughs in children's health.

4 Apr 2013

Polymer scaffolds can advance the development of cancer therapeutics

Porous polymer scaffolds fabricated to support the growth of biological tissue for implantation may hold the potential to greatly accelerate the development of cancer therapeutics.

3 Apr 2013

CRG researchers reprogramme lymphoma and leukaemia cells to halt malignancy

Researchers from the Centre for Genomic Regulation (CRG) in Barcelona reprogramme lymphoma and leukaemia cells to halt their malignancy. Resulting cells remain benign even when no longer subjected to treatment and reduce likelihood of developing new tumours.

3 Apr 2013

Engineers develop prototype telerobotic platform for bladder cancer treatment

Although bladder cancer is the sixth most common form of cancer in the U.S. and the most expensive to treat, the basic method that doctors use to treat it hasn't changed much in more than 70 years.

3 Apr 2013

Malignant News and Research

Protein helps leukemia cells avoid effects of chemotherapy by appearing dormant

John Theurer Cancer Center to host Women's Oncology Conference for gynecologists, generalists

Study: Certain types of papilloma virus might prevent cervical cancer

Conference on Malignant Hyperthermia to be held in Orlando

DelMar Pharmaceuticals reports positive results from VAL-083 Phase I/II clinical trial in patients with GBM

BRAF genetic mutation increases mortality among patients with papillary thyroid cancer

First combination treatment of microwave ablation, radiotherapy performed on 52-year-old patient

New immunotherapies are seldom developed for childhood cancer

Researchers design drug to block incidence of head, neck cancer caused by HPV virus

Researchers explore how blocking EGFR changes signaling in glioblastoma cells

Certain brain tumors develop drug resistance by exploiting normal cellular signaling pathways

Study evaluates efficacy of drug combinations in treating colorectal cancer

Physician-researcher to lead pediatric Dream Team to create new treatments for childhood cancers

A*STAR's professor receives Szent-Gy-rgyi prize for groundbreaking cancer pill

NeuroBlate Thermal Therapy System safe for treating recurrent glioblastoma, study shows

Overexpression of miR-155 promotes growth of blood vessels in tumors and metastasis

Three institutions partner to create research breakthroughs in children's health

Polymer scaffolds can advance the development of cancer therapeutics

CRG researchers reprogramme lymphoma and leukaemia cells to halt malignancy

Engineers develop prototype telerobotic platform for bladder cancer treatment

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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