Malignant News and Research

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Researchers discover new mechanism that allows collective cell migration

Researchers at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC) have discovered a new mechanism that allows some cells in our body to move together, in some ways like the tortoise formation used by Roman soldiers depicted in the Asterix series.

12 Mar 2013

New immunoassay appears to be valid screening method for early detection of renal cell carcinoma

A new immunoassay that tests for the presence of three biomarkers appears to be a valid screening method for the early detection of malignant kidney cancer, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

11 Mar 2013

Combining mitochondrial inhibitors could improve efficacy of BRAF inhibitors in melanoma

A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism.

11 Mar 2013

Global cancer problem ‘needs international solution’

Global leaders in cancer research and policy are calling on the scientific community and worldwide governments to unite against the disease.

8 Mar 2013

Researchers discover ovarian stem-like epithelial cells that can mutate to form tumors

In collaboration with colleagues at Cornell University, a team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has discovered cells with stem-cell properties in the ovary that can mutate to form tumors.

8 Mar 2013

MicroRNA expression signatures may help define progression of Barrett's esophagus

A series of microRNA expression signatures that may help to define progression of the precancerous condition Barrett's esophagus into esophageal adenocarcinoma was reported recently in Cancer Prevention Research, a journal of the American Association for Cancer Research.

7 Mar 2013

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

UT Southwestern Medical Center scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.

6 Mar 2013

People with variations in FTO gene could be at increased risk of melanoma

The research shows that people with particular variations in a stretch of DNA within the FTO gene, called intron 8, could be at greater risk of developing melanoma.

5 Mar 2013

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

In an article published as the cover story of the March 2013 issue of Nature Chemical Biology, Lindsey James, PhD, research assistant professor in the lab of Stephen Frye, Fred Eshelman Distinguished Professor in the UNC School of Pharmacy and member of the UNC Lineberger Comprehensive Cancer Center, announced the discovery of a chemical probe that can be used to investigate the L3MBTL3 methyl-lysine reader domain.

3 Mar 2013

Advanced breast cancer increasing among younger women, study finds

An analysis of breast cancer trends in the U.S. finds a small but statistically significant increase in the incidence of advanced breast cancer for women 25 to 39 years of age, without a corresponding increase in older women, according to a study appearing in the February 27 issue of JAMA.

27 Feb 2013

New research offers clues for chemotherapy-induced cognitive impairment

It's not unusual for cancer patients being treated with chemotherapy to complain about not being able to think clearly, connect thoughts or concentrate on daily tasks. The complaint - often referred to as chemo-brain - is common. The scientific cause, however, has been difficult to pinpoint.

22 Feb 2013

Researchers determine that neuroblastoma is sensitive to BET bromodomain inhibitors

Neuroblastoma, the most common malignant tumor of early childhood, is frequently associated with the presence of MYCN amplification, a genetic biomarker associated with poor prognosis. Researchers have determined that tumors containing MYCN amplification are sensitive to a new class of drugs, BET bromodomain inhibitors.

22 Feb 2013

Two new non-invasive technologies can improve early identification of tumor response to therapy

The research was published early in the January issue of the journal Technology in Cancer Research and Treatment. The article describes experiments using ultrasonic molecular imaging (USMI) and Dynamic Contrast Enhanced-Perfusion Imaging (DCE-PI) to measure response to therapy for pancreatic cancer.

21 Feb 2013

Research involves new, safer ways to deliver biomedical agents against tumors

Jeremy L. Steinbacher, PhD, is among a new generation of scientists trying to improve their aim and approach to killing cancer cells. The Canisius College professor of chemistry/biochemistry is working to develop biomedical agents that more accurately target and attack tumors.

16 Feb 2013

Researchers identify new molecular pathway involved in alveoli growth

In a study of mice, researchers at Johns Hopkins have identified a new molecular pathway involved in the growth of tiny air sacs called alveoli that are crucial for breathing. The scientists say their experiments may lead to the first successful treatments to regrow the air sacs in people who suffer from diseases such as emphysema in which the air sacs have been destroyed by years of smoking.

15 Feb 2013

EMAS publishes clinical guide on lichen sclerosus in Maturitas journal

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announced today the publication of a clinical guide by the European Menopause and Andropause Society (EMAS) in its journal Maturitas on lichen sclerosus with summary recommendations.

15 Feb 2013

Malignant News and Research

Researchers discover new mechanism that allows collective cell migration

New immunoassay appears to be valid screening method for early detection of renal cell carcinoma

Combining mitochondrial inhibitors could improve efficacy of BRAF inhibitors in melanoma

Global cancer problem ‘needs international solution’

Researchers discover ovarian stem-like epithelial cells that can mutate to form tumors

MicroRNA expression signatures may help define progression of Barrett's esophagus

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

People with variations in FTO gene could be at increased risk of melanoma

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

Advanced breast cancer increasing among younger women, study finds

New research offers clues for chemotherapy-induced cognitive impairment

Researchers determine that neuroblastoma is sensitive to BET bromodomain inhibitors

Two new non-invasive technologies can improve early identification of tumor response to therapy

Research involves new, safer ways to deliver biomedical agents against tumors

Researchers identify new molecular pathway involved in alveoli growth

EMAS publishes clinical guide on lichen sclerosus in Maturitas journal

FOXC2 vital to epithelial-mesenchymal transition in breast cancer

New medication could help patients with renal tumours triggered by tuberous sclerosis

Growth factor aids mandible reconstruction

Metastatic renal cell carcinoma (mRCC) therapy: an interview with Charles A. Nicolette, Ph.D., CSO of Argos Therapeutics

Industry Focus eBook - Cell biology (5th edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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