Precision Medicine News and Research

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Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

microRNAs (miRs) are small endogenous noncoding RNA molecules (20–23 nucleotides) derived from imperfectly paired hairpin RNA structures naturally encoded in the genome that act specifically as triggering molecules to control translational repression or mRNA degradation.

11 Mar 2016

Scientists map biological networks of genes to gain new insights on disease mechanisms

Innovative software tools allowed the scientists to construct accurate "maps" of gene networks for about 400 different human cell and tissue types, ranging from immune cells to brain tissues, whereas previous studies were limited to just one or few tissues.

11 Mar 2016

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

UNC Lineberger Comprehensive Cancer Center researchers have discovered that a deficiency in a key protein that regulates immune system warning signals could be a new biomarker for colorectal cancer, the second largest cancer killer in the United States. They believe the marker could be used to gauge response to a potential new treatment for the disease.

11 Mar 2016

Secretory capacity of human gut does not decline with age, shows study

A breakthrough in basic research and the first comprehensive study on the secretory activity of the human intestine: over a period of eight years, Dr. Dagmar Krüger of the Department of Human Biology at TU Munich has examined more than 2200 specimens from around 450 patients with bowel disease.

10 Mar 2016

Complex biomarker tests for molecularly targeted therapies lack evidentiary standards

Potentially useful biomarker tests for molecularly targeted therapies are not being adopted appropriately into clinical practice because of a lack of common evidentiary standards necessary for regulatory, reimbursement, and treatment decisions.

7 Mar 2016

Cardiac reprogramming could shrink heart scar tissue, improve patients' heart function

Patients with heart failure often have a buildup of scar tissue that leads to a gradual loss of heart function. In a new study published today in the journal Cell Stem Cell, researchers from the University of North Carolina School of Medicine report significant progress toward a novel approach that could shrink the amount of heart scar tissue while replenishing the supply of healthy heart muscle.

4 Mar 2016

Mapping family health history could drive patients to more timely screenings

Most doctors and nurses review a patient's family history to identify risk factors for heart disease and cancer, often through a paper checklist or brief interview.

4 Mar 2016

New MyGene2 web tool may help find genes influencing Mendelian disorders

A new web tool, MyGene2, will enable patients and their families to join clinicians and scientists in the search for genes underlying rare disorders. The sharing of health information also will improve knowledge about how gene variants influence symptoms and other clinical features of Mendelian disorders.

3 Mar 2016

UAB researchers focus on five key areas to improve care of CVD patients

According to the Centers for Disease Control and Prevention, approximately 610,000 people die of heart disease in the United States every year — that's one in every four deaths. The impact of cardiovascular diseases is quite large.

28 Feb 2016

Rutgers Cancer Institute physicians named as 'Top Doctor for Women's Health'

Several physicians at Rutgers Cancer Institute of New Jersey have been named as a 'Top Doctor for Women's Health' by Inside Jersey magazine.

27 Feb 2016

Discovery highlights need to improve patient education about genomics

An overwhelming majority of people with incurable cancer want to hear findings from DNA sequencing of their own tumors and normal cells, and to learn how those results may affect their health and treatment options, Dana Farber Cancer Institute scientists report.

27 Feb 2016

Vanderbilt to lead Direct Volunteers Pilot Studies under Precision Medicine Initiative Cohort Program

Federal officials with the White House and National Institutes of Health announced today that Vanderbilt University Medical Center will lead the Direct Volunteers Pilot Studies under the first grant to be awarded in the federal Precision Medicine Initiative Cohort Program.

27 Feb 2016

Luminex collaborates with University of São Paulo to validate multi-analyte Zika virus assay

Luminex Corporation today announced it is collaborating with the Laboratory of Molecular Evolution & Bioinformatics, Biomedical Sciences Institute, University of São Paulo, Brazil to validate a multi-analyte Zika virus assay developed by Luminex partner, GenArraytion, Inc.

26 Feb 2016

Research finding could lay foundation for more accurate diagnosis for rare childhood brain tumor

An international research team has identified four likely new subtypes of a rare brain tumor using molecular techniques that lay the foundation for more accurate diagnosis and tailored therapies for the hard-to-treat cancer. Scientists at St. Jude Children's Research Hospital and the German Cancer Research Center led the study, results of which appear today in the scientific journal Cell.

26 Feb 2016

Precision Medicine News and Research

Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

Scientists map biological networks of genes to gain new insights on disease mechanisms

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

Secretory capacity of human gut does not decline with age, shows study

Complex biomarker tests for molecularly targeted therapies lack evidentiary standards

Cardiac reprogramming could shrink heart scar tissue, improve patients' heart function

Mapping family health history could drive patients to more timely screenings

New MyGene2 web tool may help find genes influencing Mendelian disorders

UAB researchers focus on five key areas to improve care of CVD patients

Rutgers Cancer Institute physicians named as 'Top Doctor for Women's Health'

Discovery highlights need to improve patient education about genomics

Vanderbilt to lead Direct Volunteers Pilot Studies under Precision Medicine Initiative Cohort Program

Luminex collaborates with University of São Paulo to validate multi-analyte Zika virus assay

Research finding could lay foundation for more accurate diagnosis for rare childhood brain tumor

Four molecular subtypes of pancreatic cancer identified

Current DRG-based cost recovery system appears problematic for patients with complex disorders

SIFT 4G software can lead to faster genome analysis

Increasing medication adherence: an interview with Dr Alejandro (Alex) Jaimes

FSU researchers explore new method to decipher genetic data for new prostate cancer treatments

Scientists resolve tumor heterogeneity using innovative DEPArray technology

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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