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Research deals with important issues in the field of urolithiasi

A balance between the activation of the inflammatory macrophages and suppression of the anti-inflammatory macrophages in the kidney may play a pivotal role in kidney stone formation. These macrophage-derived mediators may have potential as biomarkers to reflect the urinary stone risk, according to a new study from Japan, which was recently presented at the recent 2nd Meeting of the EAU Section of Urolithiasis and received Clinical Research Award.

2 Oct 2013

Genetic discovery could take guesswork out of prescribing correct dose of drugs

The discovery of genetic differences affecting up to a third of the population could take the guesswork out of prescribing the correct dose of 25 percent of drugs currently on the market, researchers say.

2 Oct 2013

New insights into how obesity, type 2 diabetes can create stress response in the brain

Joslin researchers have gained new insights into how obesity and type 2 diabetes can create a stress response in the brain, especially in the hypothalamus (the brain region that regulates appetite and energy production), that may contribute to altering metabolism throughout the body. The findings are reported in the October issue of the Journal of Clinical Investigation.

2 Oct 2013

Statin medications pose no threat to short-term memory and may protect against dementia

A review of dozens of studies on the use of statin medications to prevent heart attacks shows that the commonly prescribed drugs pose no threat to short-term memory, and that they may even protect against dementia when taken for more than one year.

2 Oct 2013

Researchers take major step in development of possible treatment for stroke recovery

Researchers at The University of Texas at Dallas have taken a step toward developing a new treatment to aid the recovery of limb function after strokes.

2 Oct 2013

Final patient completion of phase II study of TR040303 in patients treated for acute myocardial infarction announced by Trophos

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for indications with under-served needs in neurology and cardiology, announces today the final patient completion of a phase II study of TR040303 in patients treated for acute myocardial infarction (MI). Outcome data of this study is expected to be available towards the end of 2013.

2 Oct 2013

Research findings show how flawed transport gene contributes to autism

Researchers say it's clear that some cases of autism are hereditary, but have struggled to draw direct links between the condition and particular genes. Now a team at the Johns Hopkins University School of Medicine, Tel Aviv University and Technion-Israel Institute of Technology has devised a process for connecting a suspect gene to its function in autism.

1 Oct 2013

FDA Approves Takeda-Lundbeck Drug For Major Depressive Disorder

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1 Oct 2013

Merck & Co. Axes 8,500 In R&D Restructuring

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1 Oct 2013

Validation of thrombin generation assay (TGA) for an IVIG drug announced by Haemtech Biopharma Services

Haemtech Biopharma Services (HBS) is pleased to announce the successful validation of a thrombin generation assay (TGA) for an IVIG drug. The assay was validated in 2012 to support the use of TGA as a release assay for Biotest Pharmaceuticals Corporation's U.S. Food and Drug Administration Biologics License Application for BIVIGAM® [Immune Globulin Intravenous (Human), 10% Liquid] product. The validated TGA assay was designed and performed on the Calibrated Automated Thrombogram® platform (CAT) from Diagnostica Stago, Inc. (Parsippany, NJ).

1 Oct 2013

Pitt scientists open door to potential research into cures for Parkinson's disease

A mix of serendipity and dogged laboratory work allowed a diverse team of University of Pittsburgh scientists to report in the Oct. 1 issue of Nature Cell Biology that they had solved the mystery of a basic biological function essential to cellular health.

1 Oct 2013

New approaches needed for testing cancer drugs

Research institutes, regulators and the pharmaceutical industry are urged to cooperate to develop new approaches to testing cancer drugs, in order to bring the revolution in personalised medicine to patients across Europe, says the European Society for Medical Oncology.

1 Oct 2013

Insulin interaction map could lead to new therapeutic targets for type 2 diabetes

A team led by scientists at The Scripps Research Institute has created the first comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete the hormone insulin. The finding makes possible a deeper scientific understanding of the insulin secretion process—and how it fails in insulin disorders such as type 2 diabetes.

1 Oct 2013

FDA grants accelerated approval to Perjeta for neoadjuvant treatment of breast cancer

The U.S. Food and Drug Administration today granted accelerated approval to Perjeta (pertuzumab) as part of a complete treatment regimen for patients with early stage breast cancer before surgery (neoadjuvant setting). Perjeta is the first FDA-approved drug for the neoadjuvant treatment of breast cancer.

1 Oct 2013

ABAM Foundation receives $2M grant to establish Center for Physician Training in Addiction Medicine

The Conrad N. Hilton Foundation has awarded the American Board of Addiction Medicine (ABAM) Foundation a three-year, $2 million grant to establish The National Center for Physician Training in Addiction Medicine.

1 Oct 2013

Liquid biopsy: New device could help doctors diagnose and treat cancers

A microfluidic chip developed at the University of Michigan is among the best at capturing elusive circulating tumor cells from blood-and it can support the cells' growth for further analysis.

1 Oct 2013

Use of cocaine may increase one's vulnerability to HIV infection

Cocaine use may increase one's vulnerability to HIV infection, according to a new research report published in the Journal of Leukocyte Biology. In the report, scientists show that cocaine alters immune cells, called "quiescent CD4 T cells," to render them more susceptible to the virus, and at the same time, to allow for increased proliferation of the virus.

1 Oct 2013

Biochemists discover promising vitamin D-based treatment that halts or reverse MS

A diagnosis of multiple sclerosis (MS) is a hard lot. Patients typically get the diagnosis around age 30 after experiencing a series of neurological problems such as blurry vision, wobbly gait or a numb foot. From there, this neurodegenerative disease follows an unforgiving course.

1 Oct 2013

Roadmap of protein interactions may lead to new therapeutic approaches for type 2 diabetes

A team led by scientists at The Scripps Research Institute (TSRI) has created the first comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete the hormone insulin.

1 Oct 2013

Battle over health law brings gov't to brink of shutdown

A stopgap bill to fund the government when the fiscal year ends Oct. 1 continues to be caught up in Republican efforts to defund, delay or derail the health law. Federal agencies have contingency plans in place.

1 Oct 2013

Drugs News and Research

Research deals with important issues in the field of urolithiasi

Genetic discovery could take guesswork out of prescribing correct dose of drugs

New insights into how obesity, type 2 diabetes can create stress response in the brain

Statin medications pose no threat to short-term memory and may protect against dementia

Researchers take major step in development of possible treatment for stroke recovery

Final patient completion of phase II study of TR040303 in patients treated for acute myocardial infarction announced by Trophos

Research findings show how flawed transport gene contributes to autism

FDA Approves Takeda-Lundbeck Drug For Major Depressive Disorder

Merck & Co. Axes 8,500 In R&D Restructuring

Validation of thrombin generation assay (TGA) for an IVIG drug announced by Haemtech Biopharma Services

Pitt scientists open door to potential research into cures for Parkinson's disease

New approaches needed for testing cancer drugs

Insulin interaction map could lead to new therapeutic targets for type 2 diabetes

FDA grants accelerated approval to Perjeta for neoadjuvant treatment of breast cancer

ABAM Foundation receives $2M grant to establish Center for Physician Training in Addiction Medicine

Liquid biopsy: New device could help doctors diagnose and treat cancers

Use of cocaine may increase one's vulnerability to HIV infection

Biochemists discover promising vitamin D-based treatment that halts or reverse MS

Roadmap of protein interactions may lead to new therapeutic approaches for type 2 diabetes

Battle over health law brings gov't to brink of shutdown

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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