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CRISPR-based system suppresses genes related to AAV antibody production

Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing sequence or enact a temporary change in its expression, but the body's immune response to AAV can thwart the whole endeavor.

4 Sep 2020

New consortium established to study the characteristics of blood cells

What's the risk of different human populations to develop a disease? To find out, a team led by Université de Montréal professor Guillaume Lettre created an international consortium to study the blood of hundreds of thousands of people worldwide.

4 Sep 2020

Researchers develop unique method to coax bone marrow stem cells into specialized cells

Researchers at the University of Illinois Chicago have developed a unique method for precisely controlling the deposition of hydrogel, which is made of water-soluble polymers commonly used to support cells in experiments or for therapeutic purposes.

4 Sep 2020

Therapeutic derived from turmeric shows promise in treating canine ocular condition

Researchers at Texas A&M University have produced a therapeutic derived from turmeric, a spice long-praised for its natural anti-inflammatory properties, that shows promise in decreasing ocular inflammation in dogs suffering from uveitis, an inflammation of the eye that leads to pain and reduced vision.

4 Sep 2020

Physician-owned practices adopt more QI strategies than hospital-owned practices

Little is known about what determines strategy implementation around quality improvement (QI) in small and medium-sized primary care practices.

4 Sep 2020

Scientists find new way to capture "live" images of immune cells inside the lungs

University of Calgary scientists have discovered how to capture "live" images of immune cells inside the lungs.

4 Sep 2020

Individual biocontainment unit protects health care workers against aerosolized SARS-CoV-2 virus

Especially in settings where personal protective equipment, or PPE, is in short supply, intubation -- inserting a breathing tube down a patient's throat -- poses a major risk of SARS-CoV-2 exposure for doctors and nurses as viral particles are released into the air.

3 Sep 2020

New training system uses IoT to motivate and track exercise intensity levels

A common notion is to walk 10,000 steps a day to improve ones' physical fitness, so pedometers have been a popular wearable health device from before the days of fitness trackers and smartphones.

3 Sep 2020

Novel fabric mask for enhanced protection and comfort

Imagine a reusable face mask that protects wearers and those around them from SARS-CoV-2, is comfortable enough to wear all day, and stays in place without frequent adjustment.

3 Sep 2020

Study shows fatty liver disease is a significant risk factor for COVID-19 hospitalization

A recent observational study by US researchers reveals that individuals with non-alcoholic fatty liver disease and steatohepatitis have increased odds of hospitalization due to coronavirus disease (COVID-19); conversely, metabolic surgery was found to be protective against the admission of infected individuals. The study is currently available on the medRxiv* preprint server.

3 Sep 2020

New intervention to help improve outcomes for adolescents with Type 1 diabetes

Adolescence is a difficult period of development, made more complex for those with Type 1 diabetes mellitus (T1DM).

3 Sep 2020

Underlying pathology of MIS-C in children following SARS-CoV-2 infection

Researchers at the Icahn School of Medicine at Mount Sinai, New York, have conducted a study that sheds light on the molecular underpinnings of multisystem inflammatory syndrome in children (MIS-C).

3 Sep 2020

New biocontainment unit could help healthcare workers caring for COVID-19 patients

The U.S. Army partnered with the University of Pittsburg Medical Center to create a biocontainment unit that could help healthcare workers caring for COVID-19 patients.

3 Sep 2020

COVID-19 vaccine candidate protects animals against SARS-CoV-2

Most people with COVID-19 have relatively mild disease, but a subset of people develop severe pneumonia and respiratory failure, potentially leading to death.

3 Sep 2020

Chest X-rays found to be highly predictive of COVID-19

A team of LSU Health New Orleans radiologists investigated the usefulness of chest X-rays in COVID-19 and found they could aid in a rapid diagnosis of the disease, especially in areas with limited testing capacity or delayed test results.

3 Sep 2020

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

The University of Chicago Medicine is launching a clinical trial to examine the potential of an antibody against the SARS-CoV-2 spike protein for treating COVID-19, the disease caused by the novel coronavirus.

3 Sep 2020

Scientists identify genetic risk factors underlying penicillin allergy

Penicillin, a life-saving medicine, is the most common cause of drug allergy, with clinical manifestations ranging from temporary skin reactions to life-threatening systemic syndromes.

3 Sep 2020

$6.6 million grant awarded to develop new device for treating mental health disorders

Researchers at the University of Minnesota Medical School have been awarded a $6.6 million grant from the National Institute of Mental Health to develop a new medical device that can treat mental health disorders in a way that has never been done before using brain rhythms.

3 Sep 2020

Study: Antibiotics have prolonged effects on breast milk microbiota in mothers of preterm infants

A team led by researchers at the University of Toronto and The Hospital for Sick Children has found that mothers of preterm babies have highly individual breast milk microbiomes, and that even short courses of antibiotics have prolonged effects on the diversity and abundance of microbes in their milk.

3 Sep 2020

Suppressing tumor's growth and spread from the inside

A new technology that allows researchers to peer inside malignant tumors shows that two experimental drugs can normalize aberrant blood vessels, oxygenation, and other aspects of the tumor microenvironment in non-small cell lung cancer, helping to suppress the tumor's growth and spread, UT Southwestern researchers report.

3 Sep 2020

Medicine News and Research

CRISPR-based system suppresses genes related to AAV antibody production

New consortium established to study the characteristics of blood cells

Researchers develop unique method to coax bone marrow stem cells into specialized cells

Therapeutic derived from turmeric shows promise in treating canine ocular condition

Physician-owned practices adopt more QI strategies than hospital-owned practices

Scientists find new way to capture "live" images of immune cells inside the lungs

Individual biocontainment unit protects health care workers against aerosolized SARS-CoV-2 virus

New training system uses IoT to motivate and track exercise intensity levels

Novel fabric mask for enhanced protection and comfort

Study shows fatty liver disease is a significant risk factor for COVID-19 hospitalization

New intervention to help improve outcomes for adolescents with Type 1 diabetes

Underlying pathology of MIS-C in children following SARS-CoV-2 infection

New biocontainment unit could help healthcare workers caring for COVID-19 patients

COVID-19 vaccine candidate protects animals against SARS-CoV-2

Chest X-rays found to be highly predictive of COVID-19

UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

Scientists identify genetic risk factors underlying penicillin allergy

$6.6 million grant awarded to develop new device for treating mental health disorders

Study: Antibiotics have prolonged effects on breast milk microbiota in mothers of preterm infants

Suppressing tumor's growth and spread from the inside

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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