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Researchers identify immune cell subset that may drive chronic inflammation

For the first time, researchers have identified that an immune cell subset called gamma delta T cells that may be causing and/or perpetuating the systemic inflammation found in normal aging in the general geriatric population and in HIV-infected people who are responding well to drugs (anti-retrovirals).

11 Dec 2018

Research findings could lead to new targets for cancer-fighting therapeutics

A molecular pathway that's frequently mutated in many different forms of cancer becomes active when cells push parts of their membranes outward into bulging protrusions, Johns Hopkins researchers report in a new study.

11 Dec 2018

New computer model predicts prostate cancer progression

An international team of cancer researchers from Denmark and Germany have used cancer patient data to develop a computer model that can predict the course of disease for prostate cancer.

11 Dec 2018

Advanced illumination expands capabilities of light-sheet microscopy

Bruker announces the launch of the Luxendo InVi SPIM AIM next-generation lattice light-sheet microscope, with an advanced illumination module (AIM).

From Bruker Nano Surfaces and Metrology 11 Dec 2018

Scientists use water molecules to track electrical activity of nerve cells

Researchers have discovered a new way to monitor electrical activity in nerve cells; by observing water molecules surrounding neuronal membranes.

11 Dec 2018

Sacrificial immune cells alert body to infection

Scientists have discovered a new mechanism by which immune cells burst to alert the body to infection with Yersinia pestis.

11 Dec 2018

Cloned antibodies show potential to treat, diagnose life-threatening fungal infections

Despite public health efforts, many people who get fungal infections in their blood streams die, even if they can be identified and treated with antifungal drugs. These therapies are often ineffective on their own and increasingly the infections are becoming resistant to treatment with some of the front line antifungal drugs.

11 Dec 2018

New method uses water molecules to unlock neurons' secrets

Neurons are brain cells that communicate with each other by sending electrochemical signals along axons. When a neuron is about to release a signal - in the form of an electric charge - it allows ions to pass through its membrane via ion channels.

11 Dec 2018

Researchers develop new system for efficiently producing human norovirus

An Osaka University-led research team has developed a system for simply and efficiently producing human norovirus. By coaxing human induced pluripotent stem cells to develop into a type of cell that usually lines the intestine, they created a cellular environment that can be used for producing the virus, studying how it interacts with human cells, and investigating potential vaccines.

11 Dec 2018

Krystal 2000 microplate design improves fluorescence and luminescence measurement

Porvair Sciences unique Krystal 2000 microplate range sets a new standard for luminescence and fluorescence assays.

From Porvair Sciences Limited 11 Dec 2018

New study reveals yin-yang personality of dopamine

For decades, psychologists have viewed the neurotransmitter dopamine as a double-edged sword: released in the brain as a reward to train us to seek out pleasurable experiences, but also a "drug" the constant pursuit of which leads to addiction.

11 Dec 2018

Researchers shed new light on how to combat Shiga and ricin toxins

Min Dong, PhD, and his lab are world experts in toxins and how to combat them. They've figured out how Clostridium difficile's most potent toxin gets into cells and zeroed in on the first new botulinum toxin identified since 1969.

11 Dec 2018

Researchers capture high-resolution X-ray and NMR image of key immune regulator

A new study by investigators from Brigham and Women's Hospital provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3).

11 Dec 2018

Slow-growing type of glioma may be vulnerable to immunotherapy, suggests study

Immunotherapy has proved effective in treating a number of cancers, but brain tumors have remained stubbornly resistant.

11 Dec 2018

Ezogabine treatment reduces motor neuron excitability in ALS patients, study shows

Brian Wainger, MD, PhD, of the Healey Center for ALS at Massachusetts General Hospital presented initial, top-level results of a recently completed phase 2 clinical trial of ezogabine (also called retigabine) on December 9 at the Motor Neurone Disease Association annual meeting in Glasgow, Scotland.

11 Dec 2018

Scientists discover cellular mechanism that triggers pneumonia in humans

The situation is relatively common, especially in winter. You come down with the flu, which lasts longer than usual. A few days later, you discover you have pneumonia.

10 Dec 2018

Novel personalized medicine tool for assessing inherited colorectal cancer syndrome risk developed

An international team of researchers led by Huntsman Cancer Institute at the University of Utah has developed, calibrated, and validated a novel tool for identifying the genetic changes in Lynch syndrome genes that are likely to be responsible for causing symptoms of the disease.

10 Dec 2018

Researchers explore how glial cells develop in the brain from neural precursor cells

Two types of cells are active in the brain: nerve cells and glial cells. The latter have long been regarded primarily as supportive cells, but it is increasingly recognized that they play an active role in the communication between neurons in the brain.

10 Dec 2018

Breast tumors recruit bone marrow cells to boost their growth, study reveals

Tel Aviv University researchers have discovered that breast cancer tumors boost their growth by recruiting stromal cells that originate in bone marrow.

10 Dec 2018

Scientists find answers to how cancer spreads

How does cancer spread? While studying human brain tumor cells, a team of scientists at the Research Institute of the McGill University Health Centre found some answers to this crucial, yet so far unanswered question.

10 Dec 2018