Protein C News and Research

RSS

New study identifies possible treatment to block deposition of calcium in arterial wall

HGPS is a rare genetic disease that affects one in every 4-8 million births. The disease is caused by a spontaneous mutation in one of the two copies (alleles) of the gene LMNA, which codes for lamin A, a protein important for the integrity and function of the envelope surrounding the cell nucleus. The mutation causes incorrect processing of the messenger RNA for lamin proteins, resulting in the synthesis of an anomalous protein, called progerin.

18 Jun 2013

HPV antibodies may help identify individuals at increased risk of HPV-related oropharynx cancer

Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils.

18 Jun 2013

Increasing red meat intake boosts risk of type-2 diabetes mellitus

Eating more red meat over time is associated with an increased risk of type-2 diabetes mellitus (T2DM) in a follow-up of three studies of about 149,000 U.S. men and women, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

18 Jun 2013

Mannitol could prevent aggregation of toxic proteins in the brain, says Tel Aviv University researcher

Mannitol, a sugar alcohol produced by fungi, bacteria, and algae, is a common component of sugar-free gum and candy. The sweetener is also used in the medical field - it's approved by the FDA as a diuretic to flush out excess fluids and used during surgery as a substance that opens the blood/brain barrier to ease the passage of other drugs.

18 Jun 2013

Pyrvinium pamoate inhibits drug-resistant prostate cancer

A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Researchers produce first genome-wide investigation of cap-independent translation

Because of their central importance to biology, proteins have been the focus of intense research, particularly the manner in which they are produced from genetically coded templates-a process commonly known as translation. While the general mechanism of translation has been understood for some time, protein synthesis can initiate by more than one mechanism. One of the least well understood mechanisms is known as cap-independent translation.

17 Jun 2013

Scientists find that psychiatric disorders may be linked to protein involved in memory formation

Researchers have discovered a pathway by which the brain controls a molecule critical to forming long-term memories and connected with bipolar disorder and schizophrenia.

17 Jun 2013

Mount Sinai researchers present several new studies at ENDO 2013

Researchers from the Icahn School of Medicine at Mount Sinai will present several new studies at ENDO 2013, The Endocrine Society's Annual Meeting & Expo from June 15-18 in San Francisco.

17 Jun 2013

New research reports that UnaG protein could lead to new liver test

Many scientists dream of making a single discovery that provides fundamental insight into nature, may be used to help save human lives, and can assist in the preservation of an endangered species. In new research reported in the journal Cell, a Japanese team is on the verge of accomplishing this nearly impossible feat.

17 Jun 2013

Mayo researchers find rheumatic condition gout may be due to flare-ups in other joints

The painful rheumatic condition gout is often associated with the big toe, but it turns out that patients at highest risk of further flare-ups are those whose gout first involved other joints, such as a knee or elbow, Mayo Clinic has found.

15 Jun 2013

Penn researchers develop variant of mu opioid painkiller receptor to overcome side effects

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves testing them on their corresponding receptors, but access to meaningful quantities of these receptors that can work in experimental conditions has always been a limiting factor.

15 Jun 2013

Researchers uncover DNA damage checkpoint used by cells to monitor oxidatively damaged DNA

In current health lore, antioxidants are all the rage, as "everybody knows" that reducing the amount of "reactive oxygen species" -- cell-damaging molecules that are byproducts of cellular metabolism -- is critical to staying healthy. What everyone doesn't know is that our bodies already have a complex set of processes built into our cells that handle these harmful byproducts of living and repair the damage they cause.

15 Jun 2013

UCSF researchers discover memory-boosting molecule in mice

Memory improved in mice injected with a small, drug-like molecule discovered by UCSF San Francisco researchers studying how cells respond to biological stress.

15 Jun 2013

New research finding raises questions about common mutant forms of JC polyomavirus

The JC polyomavirus is clearly opportunistic. It infects half the population but lethally destroys brain tissue only in immunocompromised patients - and it may be outright sneaky, too. Even as a new research paper allays fears that common mutant forms of the virus are the ones directly responsible for the disease's main attack, that same finding raises new questions about what the mutants are doing instead.

14 Jun 2013

Protein expressed during embryogenesis is responsible for cancer metastasis

A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the June 15, 2013 issue of the journal Cancer Research.

14 Jun 2013

TAU researcher develops peptide to protect and restore microtubule function

A structure called "the microtubule network" is a crucial part of our nervous system. It acts as a transportation system within nerve cells, carrying essential proteins and enabling cell-to-cell communications. But in neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's, this network breaks down, hindering motor abilities and cognitive function.

14 Jun 2013

Scientists discover key mechanism that boosts signalling function of neurons in the brain

Scientists working under the leadership of neurobiologists Nils Brose and Erwin Neher at the Max Planck Institutes of Experimental Medicine and Biophysical Chemistry in Göttingen have now discovered an important molecular mechanism that turns neurons into true masters of adaptation.

14 Jun 2013

New drug target may prevent consequences of ACL tear in athletes

Striking the likes of Chicago Bulls' Derrick Rose, L.A. Lakers' Kobe Bryant and Detroit Tigers' Victor Martinez, tears in the anterior cruciate ligament (ACL) are one of the most rampant and serious knee injuries among athletes.

14 Jun 2013

CSHL scientists solve the mystery of why some infants born with grave syndrome

By identifying a protein that acts as a genetic modifier, scientists at Cold Spring Harbor Laboratory have solved the mystery of why some infants are born with a grave syndrome consisting of cleft palate and major deformities of the skin and limbs, while other infants bearing the same predisposing genetic mutation bear little or no sign of the illness, called EEC.

14 Jun 2013

Pew Charitable Trusts selects NYU professor as Pew Scholar in Biomedical Sciences

Fei Li, an assistant professor in New York University's Department of Biology, has been selected as a Pew Scholar in the Biomedical Sciences by The Pew Charitable Trusts.

14 Jun 2013

Protein C News and Research

New study identifies possible treatment to block deposition of calcium in arterial wall

HPV antibodies may help identify individuals at increased risk of HPV-related oropharynx cancer

Increasing red meat intake boosts risk of type-2 diabetes mellitus

Mannitol could prevent aggregation of toxic proteins in the brain, says Tel Aviv University researcher

Pyrvinium pamoate inhibits drug-resistant prostate cancer

Researchers produce first genome-wide investigation of cap-independent translation

Scientists find that psychiatric disorders may be linked to protein involved in memory formation

Mount Sinai researchers present several new studies at ENDO 2013

New research reports that UnaG protein could lead to new liver test

Mayo researchers find rheumatic condition gout may be due to flare-ups in other joints

Penn researchers develop variant of mu opioid painkiller receptor to overcome side effects

Researchers uncover DNA damage checkpoint used by cells to monitor oxidatively damaged DNA

UCSF researchers discover memory-boosting molecule in mice

New research finding raises questions about common mutant forms of JC polyomavirus

Protein expressed during embryogenesis is responsible for cancer metastasis

TAU researcher develops peptide to protect and restore microtubule function

Scientists discover key mechanism that boosts signalling function of neurons in the brain

New drug target may prevent consequences of ACL tear in athletes

CSHL scientists solve the mystery of why some infants born with grave syndrome

Pew Charitable Trusts selects NYU professor as Pew Scholar in Biomedical Sciences

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News