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New cell-based profiling service from RBC and Promega

A new cell-based profiling service for drug discovery has been announced by RBC and Promega Corporation.

From Promega Corporation 27 Sep 2018

New compound promotes social interaction in laboratory mice with autism

Children with autism often find social interactions awkward, leaving them isolated. Now in a study appearing in ACS' Journal of Medicinal Chemistry, scientists report that they have discovered a first-of-its-kind compound that promotes social interaction among laboratory mice that display autistic traits.

26 Sep 2018

Researchers create inexpensive system to test for dangerous levels of lead in water

The discovery of lead in Flint, Michigan's drinking water drew renewed attention to the health risks posed by the metal. Now researchers at the University of Houston have created an inexpensive system using a smartphone and a lens made with an inkjet printer that can detect lead in tap water at levels commonly accepted as dangerous.

26 Sep 2018

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

Cerevance, a clinical-stage drug discovery and development company focused on brain diseases, today announced the start of dosing in a Phase I first-in-human clinical trial of CVN424, an oral compound being developed for symptomatic treatment of Parkinson's disease.

25 Sep 2018

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sulforhodamine 101 derivative that was previously synthesized by our group.

25 Sep 2018

Biogen and Eisai announce results of LTE Phase 1b study of aducanumab for treating MCI

Biogen and Eisai Co., Ltd. announced results from a recent analysis of the ongoing long-term extension Phase 1b study of aducanumab, an investigational treatment for mild cognitive impairment due to Alzheimer's disease and mild AD dementia.

24 Sep 2018

Safe and reliable way to handle useful but foul-smelling gas in chemical synthesis

The chemical element sulfur is an important constituent in many pharmaceuticals and, consequently, it is desirable to be able to introduce sulfur-containing fragments efficiently in a broad range of chemical compounds.

21 Sep 2018

New federally-funded research project could lead to treatments that extend human lifespan

A new federally-funded research project at the Ohio University Edison Biotechnology Institute and Heritage College of Osteopathic Medicine could lead to treatments that extend human lifespan and allow people to enjoy better health in their old age.

21 Sep 2018

New naturally occurring antibiotic found effective against Mycobacterium tuberculosis

A naturally occurring antibiotic called kanglemycin A is effective against Mycobacterium tuberculosis, the bacteria that cause tuberculosis, even in drug-resistant strains, according to an international team of researchers who used chemistry, molecular biology, microbiology, and X-ray crystallography to show how the compound maintains its activity.

21 Sep 2018

Scientists find way to boost efficacy of powerful antimalarial drug with anti-cancer medicines

Scientists have found a way to boost the efficacy of the world's most powerful antimalarial drug with the help of chemotherapy medicines, according to new research published in the journal Nature Communications.

20 Sep 2018

New system harnesses power of bubbles to destroy dangerous biofilms

Stiff microbial films often coat medical devices, household items and infrastructure such as the inside of water supply pipes, and can lead to dangerous infections.

20 Sep 2018

Cannabinoid drugs reduce perceived unpleasantness of painful stimuli and increase tolerance

Researchers in the College of Arts and Sciences have determined that cannabinoid drugs do not appear to reduce the intensity of experimental pain, but, instead, may make pain feel less unpleasant and more tolerable.

19 Sep 2018

Novel clinical trial to examine cannabis as potential treatment for essential tremor

Researchers at University of California School of Medicine are preparing to launch a novel clinical trial to examine the safety, efficacy and pharmacological properties of cannabis as a potential treatment for adults with essential tremor.

18 Sep 2018

New compound could prevent malaria parasites from maturing inside mosquito

Researchers have identified compounds that could prevent malaria parasites from being able to infect mosquitoes, halting the spread of disease.

18 Sep 2018

People battling substance use disorders may benefit from meth-relapse prevention compound

New research raises the possibility that a wider group of people battling substance use disorders may benefit from a Scripps Research-developed relapse-prevention compound than previously thought.

17 Sep 2018

New device to treat acute coronary artery perforations approved by FDA

The U.S. Food and Drug Administration today approved a device intended to treat acute coronary artery perforations, or tears in the blood vessels of the heart. The PK Papyrus Covered Coronary Stent System is the first device approved by the FDA for this indication in 17 years.

14 Sep 2018

Researchers design new medicine to treat highly aggressive pancreatic cancer

A treatment for highly aggressive and commonly fatal pancreatic cancer is being developed, reports a University of Houston researcher who has designed a new medicine that can inhibit two of the major pathways of the deadly disease.

12 Sep 2018

Discovery of unusual biosynthetic pathways could aid in the search for new natural products

Bacteria are master engineers of small, biologically useful molecules. A new study in Nature Communications has revealed one of the tricks of this microbial trade: synthesizing and then later inserting a nitrogen-nitrogen bond, like a prefabricated part, into a larger molecule.

12 Sep 2018

How 'bad' bacteria gain an upper hand in the human gut

A study has revealed that the bacterium C. difficile gains a competitive advantage over protective bacteria in the human gut by producing para-cresol.

11 Sep 2018

Improve reliability, accuracy of drug discovery process with new 3D cell analysis technology

Olympus Corporation today announced the U.S.-only launch of a new 3D cell analysis technology with ability to accurately analyze 3D cell cultures down to the nuclei, improving the reliability and accuracy of the entire drug discovery process, from compound selection to animal experimentation and clinical trials in humans.

From Evident Corporation - Life Sciences 11 Sep 2018

Compound News and Research

New cell-based profiling service from RBC and Promega

New compound promotes social interaction in laboratory mice with autism

Researchers create inexpensive system to test for dangerous levels of lead in water

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

Biogen and Eisai announce results of LTE Phase 1b study of aducanumab for treating MCI

Safe and reliable way to handle useful but foul-smelling gas in chemical synthesis

New federally-funded research project could lead to treatments that extend human lifespan

New naturally occurring antibiotic found effective against Mycobacterium tuberculosis

Scientists find way to boost efficacy of powerful antimalarial drug with anti-cancer medicines

New system harnesses power of bubbles to destroy dangerous biofilms

Cannabinoid drugs reduce perceived unpleasantness of painful stimuli and increase tolerance

Novel clinical trial to examine cannabis as potential treatment for essential tremor

New compound could prevent malaria parasites from maturing inside mosquito

People battling substance use disorders may benefit from meth-relapse prevention compound

New device to treat acute coronary artery perforations approved by FDA

Researchers design new medicine to treat highly aggressive pancreatic cancer

Discovery of unusual biosynthetic pathways could aid in the search for new natural products

How 'bad' bacteria gain an upper hand in the human gut

Improve reliability, accuracy of drug discovery process with new 3D cell analysis technology

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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