Malignant News and Research

RSS

Work stress ‘unlikely’ cause of cancer

Work-related stress is unlikely to be a major cause of cancer, say researchers who found no link between job strain and the risk for overall or site-specific malignancy.

11 Feb 2013

Case Western Reserve receives $220,000 grant to study gastric cancers

The Case Western Reserve University School of Medicine has received a $220,000 grant from the DeGregorio Family Foundation to study gastric cancers, which remain among the most deadly forms of disease.

11 Feb 2013

MicroRNA can be used to define four subtypes of triple-negative breast cancer

A new, large-scale study of triple-negative breast cancer shows that small molecules called microRNA can be used to define four subtypes of this aggressive malignancy.

11 Feb 2013

Combination of two antibodies prevents growth and spread of triple-negative breast tumors

Cancer drugs of the new, molecular generation destroy malignant breast tumors in a targeted manner: They block characteristic molecules on tumor cells - receptors for the hormones estrogen or progesterone, or a co-receptor, called HER2, that binds to many growth factors. But about one in every six breast tumors has none of these receptors. Such cancers, called triple-negative, are particularly aggressive and notoriously difficult to treat.

10 Feb 2013

Novel combination of ibrutinib and bortezomib could be effective new therapy for blood cancers

Laboratory experiments conducted by scientists at Virginia Commonwealth University Massey Cancer Center suggest that a novel combination of the drugs ibrutinib and bortezomib could potentially be an effective new therapy for several forms of blood cancer, including diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL).

7 Feb 2013

Drug-carrying nanoparticles have another hurdle to overcome - escaping the bloodstream

Many medically minded researchers are in hot pursuit of designs that will allow drug-carrying nanoparticles to navigate tissues and the interiors of cells, but University of Michigan engineers have discovered that these particles have another hurdle to overcome: escaping the bloodstream.

7 Feb 2013

Previously poorly investigated signalling pathway crucial for proliferation of prostate cancer cells

A previously poorly investigated signalling pathway is crucial for the growth and proliferation of prostate cancer cells. An international research team discovered this when studying the enzyme "soluble adenylyl cyclase" that produces the second messenger molecule cAMP.

5 Feb 2013

Risks and benefits of computed tomography in young adults

The underlying medical conditions facing young adults who undergo computed tomography (CT) exams represent a significantly greater health risk than that of radiation-induced cancer from CT, according to a new study published online in the journal Radiology.

5 Feb 2013

New method for detecting cancer by measuring elasticity of tumours

As the first countries in the world, Norway and France will be testing a completely new method for detecting cancer. This is done by measuring the elasticity of tumours. The method is called elastography. You may as well learn this new word right away; in a few years, elastography may be as common as X-rays.

4 Feb 2013

Researchers determine differences in stiffness between healthy and cancerous tissue

The texture of breast cancer tissue differs from that of healthy tissue. Using a cutting-edge tissue diagnostic device, a group of researchers in Basel, Switzerland, has determined one key difference: cancerous tissue is a mix of stiff and soft zones, whereas healthy tissue has uniform stiffness.

2 Feb 2013

Endothelial cells can trigger changes in cancer cells without direct contact

Blood vessels that supply oxygen and nutrients to tumors can also deliver something else - a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and more lethal, scientists at The University of Texas MD Anderson Cancer Center report online in Cancer Cell.

1 Feb 2013

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

CEL-SCI Corporation announced that its longstanding collaboration with Northeast Ohio Medical University has produced a new investigational breast cancer vaccine which prevents and treats a HER-2/neu expressing breast cancer tumor in a mouse model of the disease.

31 Jan 2013

Palliative care for stroke affected by age, gender, stroke type

Whether patients with stroke are referred to palliative care services depends on their age, their gender, and what type of stroke they have had, Australian study results indicate.

31 Jan 2013

Microscopic hematuria poor indicator for renal, bladder malignancy

The presence of microscopic levels of blood in the urine is unreliable as an indicator for renal or bladder cancer, report researchers.

30 Jan 2013

ADRB receptors play a direct role in Src activation by PKA-mediated mechanism

Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins - known as Src - leads to ovarian cancer progression when exposed to stress hormones. The researchers report in the current issue of Nature Communications that beta blocker drugs mitigate this effect and reduce cancer deaths by an average of 17 percent.

30 Jan 2013

Genzyme receives FDA approval for Kynamro to treat homozygous familial hypercholesterolemia

The U.S. Food and Drug Administration today approved Kynamro (mipomersen sodium) injection as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemia (HoFH).

30 Jan 2013

Colorectal cancer screening: an interview with Dr Donato F. Altomare

Colorectal cancer is a malignant neoplasm affecting the large bowel and the rectum mainly after the 5th decade of life and representing the second cause of death for cancer in western countries (the third in women). In about 15-20% of patients there is an inherited predisposition.

29 Jan 2013

Scientists identify genetic process in which normal liver cells transform into cancerous ones

A team of scientists from the Cancer Science Institute of Singapore (CSI) at the National University of Singapore (NUS) has identified a genetic process in which normal liver cells transform into cancerous ones. The finding provides new understanding into the pathogenesis of human cancers.

29 Jan 2013

Double transplants can be successful with donor lungs from heavy smokers

Lungs from carefully selected donors with a heavy smoking history can be used with good results in adult, double-lung transplants, according to a study released today at the 49th Annual Meeting of The Society of Thoracic Surgeons held at the Los Angeles Convention Center.

29 Jan 2013

KLF8 protein could be helpful in preventing cancer recurrence

Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein present in several types of cancer, including breast and ovarian cancer, which could be helpful in preventing tumors from coming back.

29 Jan 2013

Malignant News and Research

Work stress ‘unlikely’ cause of cancer

Case Western Reserve receives $220,000 grant to study gastric cancers

MicroRNA can be used to define four subtypes of triple-negative breast cancer

Combination of two antibodies prevents growth and spread of triple-negative breast tumors

Novel combination of ibrutinib and bortezomib could be effective new therapy for blood cancers

Drug-carrying nanoparticles have another hurdle to overcome - escaping the bloodstream

Previously poorly investigated signalling pathway crucial for proliferation of prostate cancer cells

Risks and benefits of computed tomography in young adults

New method for detecting cancer by measuring elasticity of tumours

Researchers determine differences in stiffness between healthy and cancerous tissue

Endothelial cells can trigger changes in cancer cells without direct contact

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

Palliative care for stroke affected by age, gender, stroke type

Microscopic hematuria poor indicator for renal, bladder malignancy

ADRB receptors play a direct role in Src activation by PKA-mediated mechanism

Genzyme receives FDA approval for Kynamro to treat homozygous familial hypercholesterolemia

Colorectal cancer screening: an interview with Dr Donato F. Altomare

Scientists identify genetic process in which normal liver cells transform into cancerous ones

Double transplants can be successful with donor lungs from heavy smokers

KLF8 protein could be helpful in preventing cancer recurrence

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News