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Scientists develop new form of aspirin to cope with resistance

Scientists are reporting development of a new form of aspirin - taken daily by about 60 million people in the United States alone to reduce the risk of heart attack and stroke - that could extend aspirin's benefits to people who may not respond to the drug. Their advance toward coping with "aspirin resistance" appears in the journal ACS Nano.

5 Sep 2013

Stress-related protein genetically linked to acceleration of Alzheimer's disease

A stress-related protein genetically linked to depression, anxiety and other psychiatric disorders contributes to the acceleration of Alzheimer's disease, a new study led by researchers at the University of South Florida has found.

5 Sep 2013

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Case Western Reserve researchers have identified a genetic factor that blocks the blood vessel inflammation that can lead to heart attacks, strokes and other potentially life-threatening events.

5 Sep 2013

£13M partnership to accelerate cancer-focused drug discovery launched by Queen's and Almac Discovery

A new -13 million partnership to accelerate cancer-focused drug discovery in Northern Ireland has been launched by Enterprise Minister Arlene Foster MLA.

5 Sep 2013

Parkin protein plays key role in destruction of bacteria that cause tuberculosis

A protein at the center of Parkinson's disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis, according to scientists led by UC San Francisco microbiologist and tuberculosis expert Jeffery Cox, PhD.

5 Sep 2013

Underweight women with CAD should gain weight to reduce risk of death

Being underweight increases the death risk of women with coronary artery disease (CAD) by 2-fold, according to research presented at the ESC Congress today by Dr Aziza Azimi from Denmark. The study suggests that underweight women with CAD should gain weight to reduce their risk of death.

5 Sep 2013

Research findings raise hope for new heart therapies

Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center recently found hope in an unlikely source - stem cells in cortical, or compact, bone.

5 Sep 2013

People with CVD more likely to take preventive medicines when combined in one pill

People are much more likely to take preventive medicines if they're combined in one pill, an international study has found. The findings are published today in the Journal of the American Medical Association.

5 Sep 2013

Neurodyn acquires all assets related to new drug candidate Memogain from Galantos Pharma

Neurodyn Inc. announced today that it has acquired from Galantos Pharma GmbH, Mainz, Germany all assets related to their Alzheimer's prescription drug candidate - Memogain. Memogain has completed an extensive preclinical development program and is ready to proceed into Phase 1 clinical trials in late 2013. The terms of the acquisition were not disclosed.

5 Sep 2013

HeartIT receives $2.5M NIH grant to develop Cloud Based Corelab of the Future

HeartIT, the global leader that pioneered the first FDA approved zero-footprint medical imaging workstation, announced today that it has received a $2.5M grant from the NIH in order to develop the "Cloud Based Corelab of the Future."

4 Sep 2013

University of Leeds to study mechanism of Prana’s PBT434 in animal models of Parkinson’s disease

Prana Biotechnology today announced that Parkinson’s UK has awarded £150,000 (AU$260,000) to The University of Leeds to study the mechanism of action of PBT434.

4 Sep 2013

Dakota Laboratories banned from manufacturing and distributing drugs

Dakota Laboratories LLC and its president, Charles L. Voellinger, Sr., are prohibited from manufacturing and distributing drugs until they correct their ongoing violations of the drug manufacturing laws.

4 Sep 2013

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

The hepatitis C virus hijacks the body's immune system, leaving T cells unable to function. A new study in animal models suggests that blocking a protein that helps the virus thrive could restore immune function, allowing the body to fight infection. The work, led by teams at The Research Institute at Nationwide Children's Hospital and Emory University, was published online Aug. 26 in the Proceedings of the National Academy of Sciences.

4 Sep 2013

Money & Medicine: Pay differential for women docs grows, big employers see health costs jump, Rx coupons are no bargain

News outlets covered various studies about health costs and doctor earnings. Female physicians in the U.S. continue to earn less than their male counterparts, with the pay gap widening during the past two decades to more than $50,000 annually in 2010, researchers said.

4 Sep 2013

RVX-208 drug fails to increase good cholesterol levels in ASSURE trial

Patients with coronary artery disease and low levels of "good cholesterol - or high-density lipoprotein - who were treated with a drug designed to increase HDL levels and reduce coronary plaque build-up, experienced no better results than those treated with placebo, according to research conducted by the Cleveland Clinic Coordinating Center for Clinical Research.

4 Sep 2013

Over half of people with hypertension unaware of the condition, very few take adequate treatment

A global study has found that many patients don't know they have hypertension and, even if they do, too few are receiving adequate drug therapy for their hypertension.

4 Sep 2013

Study: Fixed-dose combination medication helps CVD patients

In a randomized trial that included about 2,000 patients with or at high risk of cardiovascular disease (CVD), use of a fixed-dose combination medication for blood pressure, cholesterol, and platelet control compared to usual care resulted in significantly improved medication adherence after 15 months and small improvements in systolic blood pressure and low-density lipoprotein cholesterol, according to a study in the September 4 issue of JAMA.

4 Sep 2013

Microencapsulated brain cancer drug may simplify treatment and provide tightly controlled therapy

Consistently uniform, easily manufactured microcapsules containing a brain cancer drug may simplify treatment and provide more tightly controlled therapy, according to Penn State researchers.

4 Sep 2013

Viewpoints: Shortages of drugs persist; number of Medicare doctors is growing; Obamacare undermines health savings accounts

As was the case during the last debt-ceiling debacle, in 2011, playing politics with the nation's creditworthiness is irresponsible and unnecessary. Leave aside the ObamaCare obsession, because Republicans have zero chance of persuading the president to kill one of his defining achievements.

4 Sep 2013

NIH-funded study finds zebrafish model may help identify treatments for childhood epilepsy

According to new research on epilepsy, zebrafish have certainly earned their stripes. Results of a study in Nature Communications suggest that zebrafish carrying a specific mutation may help researchers discover treatments for Dravet syndrome (DS), a severe form of pediatric epilepsy that results in drug-resistant seizures and developmental delays.

4 Sep 2013

Drugs News and Research

Scientists develop new form of aspirin to cope with resistance

Stress-related protein genetically linked to acceleration of Alzheimer's disease

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

£13M partnership to accelerate cancer-focused drug discovery launched by Queen's and Almac Discovery

Parkin protein plays key role in destruction of bacteria that cause tuberculosis

Underweight women with CAD should gain weight to reduce risk of death

Research findings raise hope for new heart therapies

People with CVD more likely to take preventive medicines when combined in one pill

Neurodyn acquires all assets related to new drug candidate Memogain from Galantos Pharma

HeartIT receives $2.5M NIH grant to develop Cloud Based Corelab of the Future

University of Leeds to study mechanism of Prana’s PBT434 in animal models of Parkinson’s disease

Dakota Laboratories banned from manufacturing and distributing drugs

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

Money & Medicine: Pay differential for women docs grows, big employers see health costs jump, Rx coupons are no bargain

RVX-208 drug fails to increase good cholesterol levels in ASSURE trial

Over half of people with hypertension unaware of the condition, very few take adequate treatment

Study: Fixed-dose combination medication helps CVD patients

Microencapsulated brain cancer drug may simplify treatment and provide tightly controlled therapy

Viewpoints: Shortages of drugs persist; number of Medicare doctors is growing; Obamacare undermines health savings accounts

NIH-funded study finds zebrafish model may help identify treatments for childhood epilepsy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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