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Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Atherosclerosis is the most common cause of cardiovascular disease, and results from chronic inflammation of arterial vessel walls. An international collaboration led by Professor Christian Weber of Ludwig-Maximilians-Universität (LMU) in Munich and Privatdozentin Alma Zernecke of Würzburg University now shows that dendritic cells stimulate this process by derailing a mechanism that normally acts as a brake on immune reactions.

4 Jun 2011

Researchers identify 'epigenetic fingerprints' of healthy volunteers, patients with common diseases

Until a decade, it was believed that differences between people were due solely to the existence of genetic changes, which are alterations in the sequence of our genes. The discoveries made during these last ten years show that beings with the same genetics like the twins and cloned animals may have different characteristics and disease due to epigenetic changes.

4 Jun 2011

Johns Hopkins researchers solve long-standing mystery of Warburg effect

It's long been known that cancer cells eat a lot of sugar to stay alive. In fact, where normal, noncancerous cells generate energy from using some sugar and a lot of oxygen, cancerous cells use virtually no oxygen and a lot of sugar.

4 Jun 2011

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have demonstrated why certain immune cells chronically exposed to HIV shut down, and how they can be reactivated.

4 Jun 2011

Scientists identify chromosomal mutation responsible for excessive hair growth

Researchers in the Keck School of Medicine of the University of Southern California (USC), together with scientists in Beijing, China, have discovered a chromosomal mutation responsible for a very rare condition in which people grow excess hair all over their bodies.

4 Jun 2011

Research in progress for novel protein kinase inhibitors: GEN

Biotech scientists are working on novel protein kinase inhibitors that are targeting a host of conditions ranging from atherosclerosis to neurodegenerative diseases, reports Genetic Engineering & Biotechnology News.

4 Jun 2011

Researchers discover genomic control system that regulates gut formation in sea-urchin embryos

For all animals, development begins with the embryo. It is here that uniform cells divide and diversify, and blueprints are laid for future structures, like skeletal and digestive systems. Although biologists have known for some time that signaling processes-messages that tell a cell to express certain genes so as to become certain parts of these structures-exist at this stage, there has not been a clear framework explanation of how it all comes together.

4 Jun 2011

National Cancer Survivors Day to be held on June 5th 2011

The 24th National Cancer Survivors Day will be held on June 5th this year. "This annual event is a national recognition that we have made significant progress in the fight against cancer," said Dr. Patricia Robinson, director of Loyola University Health System's Cancer Survivorship Program. Robinson sees cancer survivors at Loyola's main campus in Maywood and at the Loyola Center for Health at Wheaton.

3 Jun 2011

Mimicry allows bacteria to evade host's defense responses

Deadly bacteria may be evolving antibiotic resistance by mimicking human proteins, according to a new study by the Translational Genomics Research Institute (TGen).

3 Jun 2011

Medical researchers uncover a novel approach to treat Huntington's disease

Medical researchers may have uncovered a novel approach to treat an incurable and ultimately fatal neurodegenerative disease that affects hundreds of thousands of people.

3 Jun 2011

'Switching off' critical disease causing gene can reestablish Rett syndrome in adult animals

An IRSF funded study published today in the journal Science has shown that the childhood disorder Rett syndrome, can be reestablished in adult animals by "switching off" a critical disease causing gene in healthy adult animals.

3 Jun 2011

Media outlets examine case of man cured of HIV, leukemia through bone marrow transplant

In a special report, Reuters examines the case of Timothy Ray Brown, who was cured of HIV and leukemia after undergoing "a bone marrow transplant using cells from a donor with a rare genetic mutation, known as CCR5 delta 32," which researchers knew conveyed resistance to HIV infection.

3 Jun 2011

Study provides insights into evolution and origins of MRSA

A distinctly new type of methicillin resistant Staphylococcus aureus (MRSA) that is not detected by traditional genetic screening methods has been discovered in patients in Irish hospitals according to research to be published in the journal Antimicrobial Agents and Chemotherapy.

3 Jun 2011

Johns Hopkins researchers solve mystery of Warburg effect

It’s long been known that cancer cells eat a lot of sugar to stay alive. In fact, where normal, noncancerous cells generate energy from using some sugar and a lot of oxygen, cancerous cells use virtually no oxygen and a lot of sugar. Many genes have been implicated in this process and now, reporting in the May 27 issue of Cell, researchers at the Johns Hopkins University School of Medicine have discovered that this so-called Warburg effect is controlled.

2 Jun 2011

Noninvasive diagnostics may offer alternative to liver biopsy for assessing liver fibrosis

Patients who are evaluated for liver diseases such as hepatitis C (HCV) are typically recommended for liver biopsy to determine the extent of disease progression. For patients who question whether less invasive testing is available, clinicians now have alternatives options to consider. Elastography and serum markers are two such diagnostic options reviewed in an editorial published in the June issue of Hepatology, a journal of the American Association for the Study of Liver Diseases.

2 Jun 2011

Sequenom secures $30.0M credit facility from Silicon Valley Bank’s San Diego-based team

Sequenom, Inc., a life sciences company providing innovative genetic analysis solutions, today announced it and its subsidiary Sequenom Center for Molecular Medicine have secured a $30.0 million financing commitment from Silicon Valley Bank’s San Diego-based team. Sequenom will use proceeds from the facility to support the development and commercialization of new products and other near term growth initiatives.

2 Jun 2011

New model can help determine physical fitness and cardiac health

Imagine being able to calculate one number that would tell you just how fit you are - and what that means for your heart health. Researchers from the Norwegian University of Science and Technology (NTNU) have managed exactly that: they have developed a model that can help doctors - and individuals - determine just how fit an individual is, and what that means for overall health.

2 Jun 2011

PCF funds 14 new Creativity Awards for advanced prostate cancer research

The Prostate Cancer Foundation today announced that it has funded 14 new Creativity Awards for advanced prostate cancer research. These two-year awards are designed to support innovative research ideas that have the potential to achieve breakthroughs for improved prostate cancer diagnosis and treatment.

2 Jun 2011

Adaptimmune announces opening of Phase I/II clinical trial in multiple myeloma

Adaptimmune announced that it has opened a Phase I/II, dual site, two-cohort, open-label clinical trial in multiple myeloma at the University of Maryland and the University of Pennsylvania testing its enhanced T cell receptor T cell therapy.

1 Jun 2011

Scientists find no link between XMRV retrovirus and human disease

Delineation of the origin of the retrovirus known as XMRV from the genomes of laboratory mice indicates that the virus is unlikely to be responsible for either prostate cancer or chronic fatigue syndrome in humans, as has been widely published.

1 Jun 2011

Genetic News and Research

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Researchers identify 'epigenetic fingerprints' of healthy volunteers, patients with common diseases

Johns Hopkins researchers solve long-standing mystery of Warburg effect

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

Scientists identify chromosomal mutation responsible for excessive hair growth

Research in progress for novel protein kinase inhibitors: GEN

Researchers discover genomic control system that regulates gut formation in sea-urchin embryos

National Cancer Survivors Day to be held on June 5th 2011

Mimicry allows bacteria to evade host's defense responses

Medical researchers uncover a novel approach to treat Huntington's disease

'Switching off' critical disease causing gene can reestablish Rett syndrome in adult animals

Media outlets examine case of man cured of HIV, leukemia through bone marrow transplant

Study provides insights into evolution and origins of MRSA

Johns Hopkins researchers solve mystery of Warburg effect

Noninvasive diagnostics may offer alternative to liver biopsy for assessing liver fibrosis

Sequenom secures $30.0M credit facility from Silicon Valley Bank’s San Diego-based team

New model can help determine physical fitness and cardiac health

PCF funds 14 new Creativity Awards for advanced prostate cancer research

Adaptimmune announces opening of Phase I/II clinical trial in multiple myeloma

Scientists find no link between XMRV retrovirus and human disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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