Protein C News and Research

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Promising approach to prevent emergence of drug-resistant forms of cancer

Re-routing anti-cancer drugs to the "power plants" that make energy to keep cells alive is a promising but long-neglected approach to preventing emergence of the drug-resistant forms of cancer - source of a serious medical problem, scientists are reporting.

24 May 2013

Common type of childhood asthma is not related to allergens and inflammation

Little is known about why asthma develops, how it constricts the airway or why response to treatments varies between patients. Now, a team of researchers at Weill Cornell Medical College, Columbia University Medical Center and SUNY Downstate Medical Center has revealed the roots of a common type of childhood asthma, showing that it is very different from other asthma cases.

24 May 2013

Neisseria meningitidis causes life threatening meningitis, meningococcal sepsis in humans

"Neisseria meningitidis is an important human pathogen that can cause rapidly progressing, life threatening meningitis and meningococcal sepsis in humans," Professor Jennings said.

24 May 2013

Researchers reveal roots of a common type of childhood asthma

24 May 2013

Lund University researchers deactivate mutated huntingtin protein in the brains of mice

Researchers at Lund University have succeeded in preventing very early symptoms of Huntington's disease, depression and anxiety, by deactivating the mutated huntingtin protein in the brains of mice.

23 May 2013

OncoGenex plans to initiate OGX-42 Phase 2 trial in patients with advanced squamous cell lung cancer

OncoGenex Pharmaceuticals, Inc. today announced plans for the initiation of the Cedar clinical trial, an investigator-sponsored, randomized, open-label Phase 2 trial evaluating OGX-427 in previously untreated patients with advanced squamous cell lung cancer.

23 May 2013

FDA gives Priority Review to Celgene's ABRAXANE sNDA for advanced pancreatic cancer

Celgene International Sàrl, a subsidiary of Celgene Corporation today announced that the U.S. Food and Drug Administration has assigned a Priority Review designation to the supplemental New Drug Application for the use of ABRAXANE (paclitaxel protein-bound particles for injectable suspension) (albumin-bound) in combination with gemcitabine for the first-line treatment of patients with advanced pancreatic cancer.

23 May 2013

Study identifies specific genetic factors that influence occurrence and severity of sepsis

A study published in the June issue of Anesthesiology represents an important first step in establishing new therapeutic options targeting specific genetic areas that influence the occurrence and severity of sepsis - a life-threatening, whole-body response to infection.

23 May 2013

Immune system attacks beneficial bacteria in several chronic human diseases

The human gut is loaded with commensal bacteria - "good" microbes that, among other functions, help the body digest food. The gastrointestinal tract contains literally trillions of such cells, and yet the immune system seemingly turns a blind eye. However, in several chronic human diseases such as inflammatory bowel disease, HIV/AIDS, cancer, cardiovascular disease, and diabetes, the immune system attacks these normally beneficial bacteria, resulting in chronic inflammation and contributing to disease progression.

23 May 2013

NIH-funded study raises hope for recovery of some adult patients with brain disorder

Scientists have reversed behavioral and brain abnormalities in adult mice that resemble some features of schizophrenia by restoring normal expression to a suspect gene that is over-expressed in humans with the illness.

23 May 2013

University of Granada researchers patent new treatment for acne

University of Granada scientists have patented a new treatment for acne that is based on completely natural substances and is much more effective than artificial formulas because it does not create resistance to bacteria and has no secondary effects.

23 May 2013

Research findings reveal promising new anti-addiction drug

Researchers at Johns Hopkins have unraveled the molecular foundations of cocaine's effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice.

23 May 2013

UC Irvine chemists create new method to identify clinically usable markers for prostate cancer in urine

Early screening for prostate cancer could become as easy for men as personal pregnancy testing is for women, thanks to UC Irvine research published today in the Journal of the American Chemical Society.

23 May 2013

Scientists make important step forward in the quest to develop universal influenza vaccine

A new approach for immunizing against influenza elicited a more potent immune response and broader protection than the currently licensed seasonal influenza vaccines when tested in mice and ferrets.

23 May 2013

GUVAX reports successful results in phase I study of oral, Escherichia coli diarrhea vaccine

The University of Gothenburg Vaccine Research Institute (GUVAX) announces successful results in a placebo controlled phase I study of an oral, inactivated Escherichia coli diarrhea vaccine.

22 May 2013

iBio announces production of vaccine candidate for new H7N9 influenza virus

iBio, Inc. today announced the production of a vaccine candidate for the newly emerged H7N9 influenza virus by an independent third party laboratory using the iBioLaunch platform.

22 May 2013

A1-PI treatment slows progression of emphysema in patients with AATD

Treatment with an Alpha-1 proteinase inhibitor (A1-PI), a naturally occurring protein that protects lung tissue from breakdown and protects the lung's elasticity, is effective in slowing the progression of emphysema in patients with Alpha-1 antitrypsin deficiency (AATD), a life-threatening genetic disorder, according to a new study presented at the 2013 American Thoracic Society International Conference.

22 May 2013

Genetic risk factor for pulmonary fibrosis can be used to identify individuals at risk for lung disease

A paper recently published in the New England Journal of Medicine and co-written by physicians and scientists at the University of Colorado School of Medicine finds that an important genetic risk factor for pulmonary fibrosis can be used to identify individuals at risk for this deadly lung disease.

22 May 2013

Rice University computational study tracks regulatory mechanisms of E. coli cells

Environment is not the only factor in shaping regulatory patterns -- and it might not even be the primary factor, according to a new Rice University study that looks at how cells' protein networks relate to a bacteria's genome.

22 May 2013

Study provides comprehensive blueprint for understanding diabetes

Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.

22 May 2013

Protein C News and Research

Promising approach to prevent emergence of drug-resistant forms of cancer

Common type of childhood asthma is not related to allergens and inflammation

Neisseria meningitidis causes life threatening meningitis, meningococcal sepsis in humans

Researchers reveal roots of a common type of childhood asthma

Lund University researchers deactivate mutated huntingtin protein in the brains of mice

OncoGenex plans to initiate OGX-42 Phase 2 trial in patients with advanced squamous cell lung cancer

FDA gives Priority Review to Celgene's ABRAXANE sNDA for advanced pancreatic cancer

Study identifies specific genetic factors that influence occurrence and severity of sepsis

Immune system attacks beneficial bacteria in several chronic human diseases

NIH-funded study raises hope for recovery of some adult patients with brain disorder

University of Granada researchers patent new treatment for acne

Research findings reveal promising new anti-addiction drug

UC Irvine chemists create new method to identify clinically usable markers for prostate cancer in urine

Scientists make important step forward in the quest to develop universal influenza vaccine

GUVAX reports successful results in phase I study of oral, Escherichia coli diarrhea vaccine

iBio announces production of vaccine candidate for new H7N9 influenza virus

A1-PI treatment slows progression of emphysema in patients with AATD

Genetic risk factor for pulmonary fibrosis can be used to identify individuals at risk for lung disease

Rice University computational study tracks regulatory mechanisms of E. coli cells

Study provides comprehensive blueprint for understanding diabetes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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