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New delivery system for combination of 2 FDA approved drugs to fight HIV

A University of Minnesota research team featuring researchers from the Institute for Molecular Virology, School of Dentistry and Center for Drug Design has developed a new delivery system for a combination of two FDA approved drugs that may serve as an effective treatment for the human immunodeficiency virus (HIV).

31 Aug 2013

Study describes lack of positive effects in drugs, long-term data and robust direct comparisons in RA

The German Institute for Quality and Efficiency in Health Care (IQWiG) examined 9 biotechnologically produced drugs for the treatment of adults with rheumatoid arthritis in whom prior pharmacological treatment had failed.

31 Aug 2013

Researchers develop model that completes bridge between cellular and human studies of schizophrenia

Schizophrenia is one of the most devastating neurological conditions, with only 30 percent of sufferers ever experiencing full recovery. While current medications can control most psychotic symptoms, their side effects can leave individuals so severely impaired that the disease ranks among the top ten causes of disability in developed countries.

31 Aug 2013

New angle for developing drugs to prevent thrombosis and heart attack

Platelets, which allow blood to clot, are at the heart of numerous cardiovascular problems, including heart attacks and stroke. New research has uncovered a key platelet protein that could offer a new angle for developing drugs to prevent thrombosis, or dangerous blood clots, in patients who are at high risk such as those with atherosclerosis or a history of heart problems.

31 Aug 2013

EEG marker unlikely to predict epilepsy death

Prolonged postictal generalized electroencephalography suppression is an “inconsistent” finding in patients with epilepsy, say researchers.

30 Aug 2013

Scientists identify protein that blocks death of high-risk acute lymphoblastic leukemia cells

St. Jude Children's Research Hospital scientists have identified a protein that certain high-risk acute lymphoblastic leukemia (ALL) cells need to survive and have used that knowledge to fashion a more effective method of killing tumor cells. The findings appear in the August 29 edition of the journal Blood.

30 Aug 2013

State highlights: Calif. dems propose alternative prison care plan; N.Y. extends managed care to cut Medicaid costs; Ga. Medicaid rolls at new high

Democratic leaders of the state Senate on Wednesday proposed an extra $200 million annually for rehabilitation, drug and mental health treatment as an alternative to Gov. Jerry Brown's plan for reducing prison crowding (McGreevy, 8/28).

30 Aug 2013

Statins offer great potential as anti-aging therapy

Not only do statins extend lives by lowering cholesterol levels and reducing the risks of cardiovascular disease, but new research in the September 2013 issue of The FASEB Journal suggests that they may extend lifespans as well. Specifically, statins may reduce the rate at which telomeres shorten, a key factor in the natural aging process. This opens the door for using statins, or derivatives of statins, as an anti-aging therapy.

30 Aug 2013

NIHR recognizes Plymouth Hospitals for promoting clinical research in NHS

Healthcare professionals and academic researchers will have the opportunity to hear from research teams at Plymouth Hospitals NHS Trust and its research partners next month.

30 Aug 2013

Findings lead to new drugs that block cancers from spreading to bone

When a cancer cell sloughs off the edge of a tumor in the breast, it faces a tough road to survive. The cell must not only remain physically intact as it rushes through blood vessels, but it also must find a new organ to lodge itself in, take in enough nutrients and oxygen to stay alive, and begin dividing, all while escaping notice by the body's immune system.

30 Aug 2013

Research: People with chronic diseases are more likely to be food insecure

Research findings provide direct evidence that people with chronic diseases are more likely to be food insecure - that is suffering from inadequate, insecure access to food as a result of financial constraints.

30 Aug 2013

Stem cell researchers receive Early Translational research awards from CIRM

Four prominent researchers from UCLA's Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational research awards totaling approximately $13 million from the California Institute for Regenerative Medicine (CIRM) the state stem cell agency. The UCLA researchers received four of the 12 total awards; no other applicant institution received more than one award.

30 Aug 2013

Texas A&M University biologist receives federal grant to study Clostridium difficile

A Texas A&M University biologist has received a federal grant to study the fecal samples of hundreds of people to better understand the gut bacteria Clostridium difficile - the cause of some 14,000 deaths a year in America - and to help lay the basic science foundation to develop drugs to combat its deadly results.

30 Aug 2013

Blood test provides tool essential to trials of therapies for Huntington's disease

An assay designed to measure normal and abnormal forms of the huntingtin protein - the mutated form of which causes Huntington's disease - was successful in detecting levels of the mutant protein in a large multicenter study of individuals at risk for the devastating neurological disorder.

30 Aug 2013

Absence or presence of single protein can make cancer cells more or less susceptible to drugs

A new weakness has been discovered in cancer cells that may make them more susceptible to chemotherapy and other treatments. In a research report appearing in the September 2013 issue of The FASEB Journal, scientists identify the HDAC5 protein as being essential for the maintenance of structures, called telomeres, within cancer cells that promote cancer cells longevity.

30 Aug 2013

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Dezima Pharma, the biotechnology company developing innovative drugs in the field of dyslipidemia, announced today the initiation of a double blind, placebo controlled, Phase 2b dose ranging study of DEZ-001 (previously TA-8995), alone and in combination with statins, in order to study the effects on a wide range of lipids and other biomarkers of cardiovascular disease in patients with mild dyslipidemia.

30 Aug 2013

Researchers discover protein that may help predict breast cancer prognosis

Researchers have identified a protein that they believe may help predict breast cancer prognosis, potentially relieving thousands of women at low risk from having to undergo painful, oft-debilitating therapies, while insuring the most successful treatments for those at high risk. The research was published ahead of print in the journal Molecular and Cellular Biology.

30 Aug 2013

Researchers discover new gene mutations which cause devastating mitochondrial disorders

Researchers have identified a novel disease gene in which mutations cause rare but devastating genetic diseases known as mitochondrial disorders.

30 Aug 2013

First Edition: August 29, 2013

Today's headlines include reports about ongoing fiscal fights surrounding efforts to raise the nation's debt limit and to defund the health law. Also, the White House enlists former President Bill Clinton to help spread the word about the overhaul.

29 Aug 2013

Future of biomedical innovation depends on new trend for all players to work together for common goal

It's a long, expensive, risky road to turn a scientific breakthrough into a treatment that can help patients. Fewer organizations are trying to tackle the challenges alone, says a new paper from MIT researchers published August 28 in the journal Science Translational Medicine.

29 Aug 2013

Drugs News and Research

New delivery system for combination of 2 FDA approved drugs to fight HIV

Study describes lack of positive effects in drugs, long-term data and robust direct comparisons in RA

Researchers develop model that completes bridge between cellular and human studies of schizophrenia

New angle for developing drugs to prevent thrombosis and heart attack

EEG marker unlikely to predict epilepsy death

Scientists identify protein that blocks death of high-risk acute lymphoblastic leukemia cells

State highlights: Calif. dems propose alternative prison care plan; N.Y. extends managed care to cut Medicaid costs; Ga. Medicaid rolls at new high

Statins offer great potential as anti-aging therapy

NIHR recognizes Plymouth Hospitals for promoting clinical research in NHS

Findings lead to new drugs that block cancers from spreading to bone

Research: People with chronic diseases are more likely to be food insecure

Stem cell researchers receive Early Translational research awards from CIRM

Texas A&M University biologist receives federal grant to study Clostridium difficile

Blood test provides tool essential to trials of therapies for Huntington's disease

Absence or presence of single protein can make cancer cells more or less susceptible to drugs

Dezima starts DEZ-001 Phase 2b study in patients with mild dyslipidemia

Researchers discover protein that may help predict breast cancer prognosis

Researchers discover new gene mutations which cause devastating mitochondrial disorders

First Edition: August 29, 2013

Future of biomedical innovation depends on new trend for all players to work together for common goal

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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