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Reformulated OxyContin®: an interview with Dr. Paul Coplan, Executive Director, Risk Management and Epidemiology, Purdue Pharma

OxyContin contains oxycodone, which is an opioid agonist. It is used for the management of moderate to severe pain when a constant opioid analgesic is needed for a prolonged period of time.

29 Aug 2013

Opioid dependence causes greatest health burden of all illicit drugs

The first ever analysis of the global and regional prevalence of dependence upon the four major categories of illicit drugs – amphetamine, cannabis, cocaine, and opioids (such as heroin) – has revealed that opioid dependence causes the greatest health burden (overall death and illness) of all the illicit drugs. The results come from new analysis of the Global Burden of Disease Study 2010, and are published in The Lancet.

29 Aug 2013

Mental and substance use disorders responsible for more death and illness worldwide

Mental and substance use disorders were the leading cause of non-fatal illness worldwide in 2010, according to a new analysis from the Global Burden of Disease Study, published in The Lancet.

29 Aug 2013

Revenue of China Nepstar Chain Drugstore for second quarter of 2013 increased by 3.4%

China Nepstar Chain Drugstore Ltd. (NYSE: NPD) ("Nepstar" or the "Company"), the largest retail drugstore chain in China based on the number of directly operated stores, today announced its unaudited financial results for the second quarter ended June 30, 2013.

29 Aug 2013

Patients attending specialist nurse clinics do not get inferior treatment to that offered by rheumatologists

Patients attending clinical nurse specialist clinics do not get inferior treatment to that offered by consultant rheumatologists, the results of a major new clinical trial have revealed.

29 Aug 2013

Scientists create polymer additives that enhance orally administered drugs to reach bloodstream

All too often, when a person takes a pill full of a potent and effective drug, the drug passes straight through the body, not reaching the organ where it is needed - a waste of money and inconvenient if it is a cold medicine, but potentially dire if it is a treatment for a serious illness.

29 Aug 2013

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Pulmonary hypertension, a deadly form of high blood pressure that develops in the lungs, may be caused by an inflammation-producing molecular pathway that damages the inner lining of blood vessels, according to a new study by researchers at the Stanford University School of Medicine.

29 Aug 2013

Loyola's success in implementing standard of care for heart attack patients recognized by AHA

Loyola University Medical Center has received the American Heart Association's Mission: Lifeline Silver Receiving Quality Achievement Award, which recognizes Loyola's commitment and success in implementing an exceptional standard of care for heart attack patients.

29 Aug 2013

Barber pole worm genome provides essential platform to understand drug resistance in worms

Researchers have identified five enzymes that are essential to the survival of a parasitic worm that infects livestock worldwide and is a great threat to global food security. Two of these proteins are already being studied as potential drug targets against other pathogens.

29 Aug 2013

Researchers develop new opioid drug for chronic pain

A team of researchers led by Andrew Coop, PhD, professor and chair of the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy, has developed a new opioid drug that shows great potential to advance treatment and improve quality of life for individuals living with chronic pain.

29 Aug 2013

Problems with key enzymes potentially lead to autism spectrum disorder

Problems with a key group of enzymes called topoisomerases can have profound effects on the genetic machinery behind brain development and potentially lead to autism spectrum disorder, according to research announced today in the journal Nature.

29 Aug 2013

Fewer children in UK diagnosed with ADHD than in USA

New research suggests that children are far less likely to be diagnosed with Attention deficit hyperactivity disorder in the UK than they are in the USA. However, the same study, led by the University of Exeter Medical School, suggests that autism diagnosis is still rising.

29 Aug 2013

Reversing inflammation in fluid near brain's cortex may provide solution to Parkinson's disease

Reversing inflammation in the fluid surrounding the brain's cortex may provide a solution to the complex riddle of Parkinson's, according to researchers who have found a link between pro-inflammatory biomarkers and the severity of symptoms such as fatigue, depression and anxiety in patients with the chronic disease.

29 Aug 2013

Endo Eyes Generics Growth With $225M Boca Pharmacal Acquisition

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28 Aug 2013

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Aug 2013

Use of antipsychotics down among nursing home residents

A two-year effort by the federal government and the nursing-home industry has reduced the use of powerful antipsychotic drugs among elderly nursing-home residents, but the decline fell short of the program's goal, according to U.S. officials (Lagnado, 8/26).

28 Aug 2013

Study shows ABL kinases have enhanced expression and activity in CML

Chronic Myelogenous Leukemia (CML) is a cancer of the white blood cells that is most commonly found in adults and in the elderly. Its incidence has been estimated to be 1 to 2 in 100,000 people. CML was the first cancer to be associated with a genetic abnormality, known as the Philadelphia Chromosome, which 95% of all CML patients carry in their cells.

28 Aug 2013

Study shows genetic test to classify gastric cancers and match them to therapies offer best outcomes

Stomach cancer, one of the leading causes of cancer death worldwide, actually falls into three broad subtypes that respond differently to currently available therapies, according to researchers at Duke-NUS Graduate Medical School Singapore.

28 Aug 2013

New polymer additives enhance ability of oral drugs to reach bloodstream

All too often, when a person takes a pill full of a potent and effective drug, the drug passes straight through the body, not reaching the organ where it is needed — a waste of money and inconvenient if it is a cold medicine, but potentially dire if it is a treatment for a serious illness.

28 Aug 2013

Genetic variant linked with increased risk of CHD in type 2 diabetic patients

Joslin scientists, in collaboration with researchers from the Harvard School of Public Health and Italian research institutes, have identified a previously unknown genetic variant associated with an increased risk of coronary heart disease (CHD) in type 2 diabetic patients.

28 Aug 2013

Drugs News and Research

Reformulated OxyContin®: an interview with Dr. Paul Coplan, Executive Director, Risk Management and Epidemiology, Purdue Pharma

Opioid dependence causes greatest health burden of all illicit drugs

Mental and substance use disorders responsible for more death and illness worldwide

Revenue of China Nepstar Chain Drugstore for second quarter of 2013 increased by 3.4%

Patients attending specialist nurse clinics do not get inferior treatment to that offered by rheumatologists

Scientists create polymer additives that enhance orally administered drugs to reach bloodstream

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Loyola's success in implementing standard of care for heart attack patients recognized by AHA

Barber pole worm genome provides essential platform to understand drug resistance in worms

Researchers develop new opioid drug for chronic pain

Problems with key enzymes potentially lead to autism spectrum disorder

Fewer children in UK diagnosed with ADHD than in USA

Reversing inflammation in fluid near brain's cortex may provide solution to Parkinson's disease

Endo Eyes Generics Growth With $225M Boca Pharmacal Acquisition

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

Use of antipsychotics down among nursing home residents

Study shows ABL kinases have enhanced expression and activity in CML

Study shows genetic test to classify gastric cancers and match them to therapies offer best outcomes

New polymer additives enhance ability of oral drugs to reach bloodstream

Genetic variant linked with increased risk of CHD in type 2 diabetic patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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