Laboratory News and Research

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New Hybrid virus may aid treatment of cancer

Researchers at The University of Texas M. D. Anderson Cancer Center have created a new class of hybrid virus and demonstrated its ability to find, highlight, and deliver genes to tumors in mice.

26 Apr 2006

Anthrax killed by protein that explodes cell walls

Not all biological weapons are created equal. They are separated into categories A through C, category A biological agents being the scariest: They are easy to spread, kill effectively and call for special actions by the pubic health system. One of these worrisome organisms is anthrax, which has already received its fair share of media attention. But work in Vince Fischetti's laboratory at Rockefeller University suggests that a newly discovered protein could be used to fight anthrax infections and even decontaminate areas in which anthrax spores have been released.

26 Apr 2006

Blood cancers may be caused by inactivation of a "tumor suppressor" gene

The discovery of a gene, called PRDM1, as a tumor suppressor sheds new light on the cause - and possible treatment - of diffuse large B-cell lymphomas (DLBCLs), a cancer of the blood's B-lymphocytes. DLBCLs comprise about 30 percent of non-Hodgkin's lymphomas.

25 Apr 2006

Beams of light used to move, select and trap protein molecules

A paper that outlines a new method to use a beam of light to trap protein molecules and make them dance in space has earned a place in the Proceedings of the National Academy of Sciences Early Edition.

25 Apr 2006

Vaginal gel zaps AIDS virus - gives women control

According to the researchers if current trials are satisfactory, a safe and effective gel which protects women from the AIDS virus may be available by 2010.

24 Apr 2006

Novel approach used to neutralize anthrax toxin

Researchers from Rensselaer Polytechnic Institute and the University of Toronto have designed a nanoscale assembly of molecules that successfully counteracts and inhibits anthrax toxin in animal and laboratory experiments.

23 Apr 2006

Scientists clarify role of phosphatase and tensin homolog tumor suppressor gene

Jiwang Zhang, Ph.D., formerly a Senior Research Associate at the Stowers Institute for Medical Research, and Linheng Li, Ph.D., Associate Investigator, are credited as the first and last authors, respectively, on a paper highlighting several previously unknown functions of phosphatase and tensin homolog (PTEN), an important tumor suppressor gene.

23 Apr 2006

Study reveals findings on how insulin-producing beta cells grow and function

A new Joslin Diabetes Center-led study has shown conclusively that two receptors in the insulin-producing beta cell do not affect developmental growth, refuting a long-held hypothesis in diabetes research.

23 Apr 2006

Protein discovery opens up new therapeutic possibilities for epilepsy and neurodegenerative diseases

UC Irvine researchers have found that a protein best known for building connections between nerve cells and muscle also plays a role in controlling brain cell activity.

23 Apr 2006

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

A team of scientists from Lawrence Berkeley National Laboratory and the Scripps Research Institute has determined the crystal structure and molecular mechanisms of a key part of WRN, a protein that protects humans from premature aging and cancer.

23 Apr 2006

Australian scientists tackle deadly Q fever

Scientists at James Cook University have taken the lead in developing a new vaccine against a highly infectious cattleyard disease caused by a bacteria which has the potential to be developed as a bioterrorist weapon.

20 Apr 2006

Magnetic nanotechnology holds promise in fighting cancer

Detecting cancer and reinventing computing are two challenges that seemingly have little, if anything, to do with each other. That is, unless you are a nanotechnologist like Shan Wang, an associate professor of materials science and engineering and of electrical engineering at Stanford.

20 Apr 2006

Genetic data from an island population proves to be a useful tool in understanding disease

With fewer than 4,000 residents, the genetically isolated Micronesian island of Kosrae, in the West Pacific, provides an ideal population in which to research heritability of disease.

20 Apr 2006

Muscles burn lactic acid as well as carbos

In the lore of marathoners and extreme athletes, lactic acid is poison, a waste product that builds up in the muscles and leads to muscle fatigue, reduced performance and pain.

20 Apr 2006

New method designed to analyze the genes that regulate the immune system

Seattle scientists have developed a new method for analyzing the Major Histocompatibility Complex (MHC) of the human genome.

20 Apr 2006

Activity levels - not food intake - most strongly correlates with weight gain in adulthood

Research conducted at the Oregon National Primate Research Center reveals that an individual's activity level is the most constant factor in predicting weight gain over adulthood.

20 Apr 2006

Bubonic plague confirmed in Los Angeles woman

Los Angeles County health officials have confirmed a case of bubonic plague in an adult woman. This is the first human case of plague in a Los Angeles County resident since 1984.

19 Apr 2006

Commercial fishermen do not face significant health risks from routine occupational exposure to Pfiesteria in estuaries

According to a study recently accepted for publication by Environmental Health Perspectives, researchers found no correlation between specific human health effects in "watermen" (commercial fishermen) and low-level exposure to the dinoflagellate Pfiesteria in areas of the Chesapeake Bay.

19 Apr 2006

Fast tracking the healing process for common ear infections

The research will aim to understand why some eardrums heal by themselves (and why some do not heal at all) by identifying which genes are responsible for the wound-healing process of an infected human ear drum.

18 Apr 2006