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Study reveals how SARS-CoV-2 infection of macrophages promotes inflammatory responses

Dysregulation of macrophages during SARS-CoV-2 infection and the over-exuberant production of pro-inflammatory cytokines by these macrophages has been hypothesized to contribute to severity of COVID-19 disease.

25 Oct 2022

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

What is the efficacy of mulberry component Kuwanon C against COVID-19?

A recent study determined the underlying antiviral mechanism of KC associated with the inhibition of SARS-CoV-2.

24 Oct 2022

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

Researchers evaluated imprinted antibody responses against SARS-CoV-2 Omicron sublineages.

24 Oct 2022

Relationship between COVID-19 and chilblains

A recent study discusses the associations between chilblains and COVID-19.

23 Oct 2022

How does COVID-19 and its treatment affect testicular function?

Researchers summarized available information related to the reproductive effects of COVID-19 in men.

23 Oct 2022

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Researchers demonstrated the structural basis of how the receptor-binding domain nested Omicron mutations have adapted to mouse angiotensin-converting enzyme 2 rather than human ACE2.

22 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

Exploring SARS-CoV-2-associated endothelial dysfunction

A new study described the evidence, mechanisms, and therapies for endothelial dysfunction in coronavirus disease 2019 (COVID-19).

21 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

In a recent study posted to the bioRxiv* preprint server, researchers at Ohio State University and the University of Texas Medical Branch assessed the underlying mechanisms involved in the fusogenicity and endosomal entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

20 Oct 2022

Licorice root extract shows potential as a COVID-19 treatment

A recent study explores the activity of glycyrrhizin against SARS-CoV-2.

19 Oct 2022

Does skin inflammation exacerbate COVID-19?

In a new study, researchers discussed inflammation during infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Oct 2022

Study explores the effect of COVID-19 on platelet function

A new study posted in the pre-print server bioRxiv* aimed to analyze the impact of COVID-19 on platelet proteome and relate the functional responses of platelets and the formation of platelet-neutrophil aggregate in hospitalized COVID-19 patients.

17 Oct 2022

High TNF receptors levels could predict COVID-19 mortality and disease severity

High levels of TNFR might successfully predict the increased severity of COVID-19.

16 Oct 2022

Transition in the management of COVID-19

A review of the current approaches to managing COVID-19, including diagnostic, therapeutic, and preventive measures.

16 Oct 2022

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

In a new study, researchers discussed the therapeutic potential of Panax ginseng for COVID-19 (coronavirus disease 2019)-induced neurological diseases.

14 Oct 2022

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Researchers developed a human endogenous retrovirus (HERV)-enveloped recombinant baculoviral DNA vaccine to target the SARS-CoV-2 Delta variant, and tested its cross-protection efficacy using mice models.

13 Oct 2022

Study explores cell signaling dysregulation and COVID-19 severity

Researchers assessed the impact of dysregulation in cell signaling events on coronavirus disease 2019 (COVID-19) severity.

12 Oct 2022

Metformin reduces risk of severe COVID-19 in diabetic patients

A new study determines whether antidiabetic agents can reduce complications in COVID-19 patients with diabetes.

10 Oct 2022

ACE2 News and Research

Study reveals how SARS-CoV-2 infection of macrophages promotes inflammatory responses

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

What is the efficacy of mulberry component Kuwanon C against COVID-19?

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

Relationship between COVID-19 and chilblains

How does COVID-19 and its treatment affect testicular function?

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Exploring SARS-CoV-2-associated endothelial dysfunction

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

Licorice root extract shows potential as a COVID-19 treatment

Does skin inflammation exacerbate COVID-19?

Study explores the effect of COVID-19 on platelet function

High TNF receptors levels could predict COVID-19 mortality and disease severity

Transition in the management of COVID-19

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Study explores cell signaling dysregulation and COVID-19 severity

Metformin reduces risk of severe COVID-19 in diabetic patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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