Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Adding chemotherapy to radiotherapy does not improve outcomes for cervical cancer patients

Results from the NRG Oncology GOG-0263 phase III clinical trial testing the addition of cisplatin-based chemotherapy to adjuvant radiotherapy following radical hysterectomy and lymphadenectomy for patients with early-stage, intermediate-risk cervical carcinoma indicated that the addition of chemotherapy did not improve outcomes for patients and led to increased toxicity for patients.

14 Mar 2025

Novel cyclic peptide antagonist can be a promising therapeutic approach for MASH

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

14 Mar 2025

Pitt study uncovers a novel trigger of deadly form of ovarian cancer

Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.

14 Mar 2025

Impact of excessive alcohol consumption on digestive health

Excessive alcohol consumption is a significant public health concern, responsible for approximately 6% of all deaths and contributing to 5.1% of the global disease burden.

12 Mar 2025

Examining skin cancer risk perceptions and reported sunburns among U.S. adults

Skin cancer is the most common cancer in the United States and a significant health issue, with millions of non-melanoma cases and tens of thousands of melanomas diagnosed annually. Furthermore, treating skin cancer costs the U.S. approximately $8.9 billion annually.

12 Mar 2025

New treatment option for advanced thymic carcinoma shows promise

Thymic epithelial tumors are a rare group of malignancies originating in the thymus gland, that includes thymoma and thymic carcinoma.

12 Mar 2025

Nwd1 gene linked to liver dysfunction in metabolic disease

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

11 Mar 2025

Deciphering the tumor-immune interplay in endometrial carcinoma

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which tumor-infiltrating immune cells regulate endometrial carcinoma (EC). As one of the most prevalent gynecological cancers, EC continues to challenge researchers and clinicians due to its dynamic interaction with the immune microenvironment.

11 Mar 2025

Ovarian cancer mutations across populations show similarities and unique differences

An extensive tumor genomic analysis of individuals with ovarian cancer, led by researchers from Huntsman Cancer Institute at the University of Utah (the U) and Emory University, revealed that Black women have nearly identical mutations to other previously studied populations.

10 Mar 2025

Unraveling the genetic differences between LUAD and LUSC in lung cancer

Lung cancer remains one of the leading causes of cancer-related mortality, with lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) representing the most prevalent subtypes of non-small cell lung cancer (NSCLC).

8 Mar 2025

Novel treatment approach shows promise for advanced HPV-negative head and neck cancer

Researchers from the University of Chicago Medicine Comprehensive Cancer Center demonstrated the potential of a novel treatment approach including immunotherapy to treat advanced human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC).

7 Mar 2025

Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more severe forms of liver disease by regulating hepatic lipid homeostasis and cellular maintenance processes.

6 Mar 2025

Breakthrough study defines ideal interval for immunotherapy and liver transplants

Hepatocellular carcinoma (HCC) represents about 80 to 90% of cases of primary liver cancer. On a global level, 905,700 new cases and 830,200 deaths were registered in 2020 according to the World Health Organization.

6 Mar 2025

Researchers develop magnetic nanoparticles for precise cancer treatment

Traditionally, radiation, chemotherapy, and surgery have been the most common ways to remove and destroy malignant cells.

6 Mar 2025

UC San Diego researchers discover new way to predict breast cancer spread

By assessing how "sticky" tumor cells are, researchers at the University of California San Diego have found a potential way to predict whether a patient's early-stage breast cancer is likely to spread.

5 Mar 2025

New drug candidate may help combat metabolic dysfunction-associated steatotic liver disease

A study published in Nature Aging has revealed a promising new drug candidate that may help combat metabolic dysfunction-associated steatotic liver disease (MASLD), a chronic liver condition that disproportionately affects communities in San Antonio due to high rates of obesity and diabetes.

5 Mar 2025

Carcinoma News and Research

Further Reading

Adding chemotherapy to radiotherapy does not improve outcomes for cervical cancer patients

Novel cyclic peptide antagonist can be a promising therapeutic approach for MASH

Pitt study uncovers a novel trigger of deadly form of ovarian cancer

Impact of excessive alcohol consumption on digestive health

Examining skin cancer risk perceptions and reported sunburns among U.S. adults

New treatment option for advanced thymic carcinoma shows promise

Nwd1 gene linked to liver dysfunction in metabolic disease

Deciphering the tumor-immune interplay in endometrial carcinoma

Ovarian cancer mutations across populations show similarities and unique differences

Unraveling the genetic differences between LUAD and LUSC in lung cancer

Novel treatment approach shows promise for advanced HPV-negative head and neck cancer

Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Breakthrough study defines ideal interval for immunotherapy and liver transplants

Researchers develop magnetic nanoparticles for precise cancer treatment

UC San Diego researchers discover new way to predict breast cancer spread

New drug candidate may help combat metabolic dysfunction-associated steatotic liver disease

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Review sheds light on the mechanistic role of long non-coding RNAs in liver disease

Exploring the molecular characteristics of hepatic biliary adenofibroma

New ASTRO guideline offers radiation therapy recommendations for anal cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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