Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Study determines the diagnostic utility of liver stiffness measurement

Even after chronic hepatitis C has been cured, portal hypertension remains the major factor driving the development of complications in advanced liver disease. In cooperation with researchers from Spain, a research team led by Georg Semmler and Mattias Mandorfer from the Division of Gastroenterology and Hepatology at MedUni Vienna's Department of Medicine III showed that the non-invasive tests explored in their earlier studies accurately estimate the probability of sequelae.

3 Nov 2022

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

Researchers examined virus-virus interactions using human lung cells coinfected with two co-circulating respiratory infection-causing viruses, respiratory syncytial virus (RSV) and influenza A virus (IAV).

1 Nov 2022

Study shows potential for eliminating surgery in a small subset of breast cancer patients

Researchers evaluate the efficacy of radiotherapy in patients with early-stage HER2-positive breast cancer or TNBC after neoadjuvant systemic therapy.

27 Oct 2022

Large genome-wide association study on nonalcoholic fatty liver disease

Scientists at deCODE genetics in Iceland have discovered rare, protective loss-of-function variants that point to potential drug targets for nonalcoholic fatty liver disease (NAFLD).

24 Oct 2022

Combination of radiation and systemic therapy can prolong survival for advanced liver cancer patients

Adding radiation therapy to systemic therapy for patients with advanced liver cancer can extend overall survival and delay tumor progression without compromising patients' quality of life, a randomized phase III clinical trial shows.

24 Oct 2022

Breakthrough discovery is a 'major step forward' in understanding cervical cancer

Scientists have discovered that cervical cancer can be divided into two distinct molecular subgroups – one far more aggressive than the other – as part of the largest 'omics' study of its kind, led by researchers at UCL and the University of Southampton.

21 Oct 2022

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

The process of metastasis is when cancer cells gain motility and spread to other sites of the body. Because this is one of the main causes of cancer-related deaths, researchers have aimed to develop therapeutic strategies that can block metastasis.

18 Oct 2022

Multi-center analysis shines light on invasive lobular carcinoma

A multi-center analysis of patients with invasive lobular carcinoma, or ILC -; the second most common histological subtype of invasive breast cancer in the U.S. -; showed that, despite its prevalence, ILC is detected later and has worse outcomes than the predominant subtype of invasive breast cancer, known as invasive ductal carcinoma (IDC), or no special type.

14 Oct 2022

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Researchers demonstrated that tumor cells evade immunotherapy by generating unique transient cell-in-cell structures, resistant to chemotherapy and destruction by T cells.

5 Oct 2022

Consumption of highly refined fiber may increase liver cancer risk in some people

Many people commonly consume fiber-enriched foods to promote weight loss and prevent chronic diseases such as diabetes and cancer.

26 Sep 2022

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

The multitargeted tyrosine kinase inhibitor (MKI), lenvatinib, is widely used to treat advanced and metastatic thyroid cancer. However, the molecular mechanisms by which thyroid cancer cells become resistant to lenvatinib remain poorly understood. In this study, we demonstrated, for the first time, that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells.

14 Sep 2022

Review highlights the role of retinol-binding protein-4 in non-alcoholic fatty liver disease

It is a known fact that consuming a large amount of alcohol, even for a few days, triggers fat accumulation in the liver and ultimately leads to alcohol-related liver diseases.

13 Sep 2022

Trained radiographers perform just as well as radiologists in double reading screening mammograms

When double reading screening mammograms, radiographers (technologists) trained for the task perform as well as radiologists in key areas, according to a study published in Radiology, a journal of the Radiological Society of North America (RSNA).

13 Sep 2022

Immunotherapy before surgery improves outcomes in many patients with stage II–IV cutaneous squamous cell carcinoma

In an international, multicenter Phase II clinical trial led by The University of Texas MD Anderson Cancer Center, 63.3% of patients with stage II–IV cutaneous squamous cell carcinoma (CSCC) saw their tumors nearly or completely disappear when treated with immunotherapy before surgery.

13 Sep 2022

MSK researchers reveal a promising treatment option for bladder cancer patients

Researchers from Memorial Sloan Kettering Cancer Center (MSK) shared a promising treatment option for bladder cancer patients today at The European Society for Medical Oncology (ESMO) Congress 2022.

13 Sep 2022

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

In a recent study posted to the medRxiv* preprint server, researchers in Australia determined whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta-ORF7aΔ17del [open reading frame 7a protein with 17-nucleotide (nt) frameshift-inducing deletion] variant has a fitness advantage over the Delta variant lacking the ORF7aΔ17del deletion (Delta-ORF7aintact) and/or the SARS-CoV-2 lineage (A.2.2).

12 Sep 2022

Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

Carcinoma News and Research

Further Reading

Study determines the diagnostic utility of liver stiffness measurement

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

Study shows potential for eliminating surgery in a small subset of breast cancer patients

Large genome-wide association study on nonalcoholic fatty liver disease

Combination of radiation and systemic therapy can prolong survival for advanced liver cancer patients

Breakthrough discovery is a 'major step forward' in understanding cervical cancer

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

Multi-center analysis shines light on invasive lobular carcinoma

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Consumption of highly refined fiber may increase liver cancer risk in some people

Signal transduction via the EGFR pathway likely to be involved in lenvatinib resistance

Review highlights the role of retinol-binding protein-4 in non-alcoholic fatty liver disease

Trained radiographers perform just as well as radiologists in double reading screening mammograms

Immunotherapy before surgery improves outcomes in many patients with stage II–IV cutaneous squamous cell carcinoma

MSK researchers reveal a promising treatment option for bladder cancer patients

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

Blocking FNDC5 prevents cancer-induced cachexia in mice

Study identifies new therapeutic target against lung adenocarcinoma

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

Triplet therapy slows progression of advanced kidney cancer

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

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