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Genetic-code expansion technique to potentially create next-generation vaccine candidate

A new experiment devised a novel method to manipulate virulent viruses in conventional laboratories and validated the prophylactic effect of this method in two mouse models.

13 Dec 2021

Study demonstrates SARS-CoV-2 ORF6 localization and interferon antagonism as independent events

Researchers deploy mutagenesis studies to investigate the relationship between ORF6 localization and IFN antagonism.

12 Dec 2021

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

Researchers have screened several compounds that could show the ability to inhibit SARS-CoV-2.

10 Dec 2021

New approach to enhance the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

7 Dec 2021

Metrion Biosciences expands ion channel drug discovery service capabilities and in-house expertise

Metrion today announced it has expanded its capabilities and expertise through the addition of automated low volume liquid handling capability.

From Metrion Biosciences Limited 7 Dec 2021

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

New strategy for antibodies to distort viruses discovered

It is widely understood that antibodies neutralize viruses by latching onto their surfaces and blocking them from infecting host cells.

30 Nov 2021

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

Study on molnupiravir precursor NHC antiviral activity against SARS-CoV-2 variants of concern

In a new study, published on the bioRxiv* preprint server, scientists aimed to determine the reaction of the molnupiravir parent drug (NHC) to different SARS-CoV-2 Variants of Concern (VoCs). They also sought to establish the therapeutic window in a human lung cell model.

29 Nov 2021

Glycosylation and disulfide bonding profile of SARS-CoV-2 spike glycoprotein

Researchers found that virus-like particles produced by co-expression of SARS-CoV-2 S, membrane, envelope, and nucleocapsid proteins contain S glycoproteins, which are modified by complex carbohydrates.

29 Nov 2021

Study finds atazanavir inhibits main SARS-CoV-2 protease

Research shows that ATV has different antiviral activity compared to PAXLOVID™, encouraging further research.

29 Nov 2021

New technique may be a significant leap forward in the understanding of human cells

Most human diseases can be traced to malfunctioning parts of a cell — a tumor is able to grow because a gene wasn't accurately translated into a particular protein or a metabolic disease arises because mitochondria aren't firing properly, for example. But to understand what parts of a cell can go wrong in a disease, scientists first need to have a complete list of parts.

24 Nov 2021

Cell Line News and Research

Genetic-code expansion technique to potentially create next-generation vaccine candidate

Study demonstrates SARS-CoV-2 ORF6 localization and interferon antagonism as independent events

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

New approach to enhance the therapeutic efficacy of liver cancer immunotherapy

Metrion Biosciences expands ion channel drug discovery service capabilities and in-house expertise

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

New strategy for antibodies to distort viruses discovered

Potentially neurotoxic SARS-CoV-2 protein fragments

Study on molnupiravir precursor NHC antiviral activity against SARS-CoV-2 variants of concern

Glycosylation and disulfide bonding profile of SARS-CoV-2 spike glycoprotein

Study finds atazanavir inhibits main SARS-CoV-2 protease

New technique may be a significant leap forward in the understanding of human cells

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Interferon beta versus the SARS-CoV-2 Delta variant

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

MIT researchers uncover a possible new way to combat tumors

Toll-like receptor 2 - novel target for improved COVID-19 vaccines

P681H mutation helps SARS-CoV-2 VOCs replicate faster and resist innate immunity

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

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