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How SARS-CoV-2 infection progresses throughout the respiratory system

Researchers discuss the progression of SARS-CoV-2 infection throughout the respiratory epithelium.

9 Feb 2022

Researchers discover a new function of anti-HIV-1 antibodies

Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures.

6 Feb 2022

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

A University of South Florida Health preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

31 Jan 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

Researchers from the University of California, Irvine have discovered that the absence of Adiponectin receptor 1 protein (AdipoR1), one of the principal enzymes regulating ceramide homeostasis in the retina, leads to an accumulation of ceramides in the retina, resulting in progressive photoreceptor cell death and ultimately vision loss.

28 Jan 2022

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

A study recently identified Neurolipin-1 or NRP1, a host factor for SARS-CoV-2 infection, as a cargo retrograde-transported by the ESCPE-1.

26 Jan 2022

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Scientists report that they have built a living "minimal cell" with a genome stripped down to its barest essentials – and a computer model of the cell that mirrors its behavior.

20 Jan 2022

Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

A new study suggests that coronaviruses such as SARS-CoV-2 depend on a furin cleavage site between the S1/S2 subunits to enhance viral infectivity.

20 Jan 2022

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

In a new study, researchers discuss the role of calcium signaling pathways as targets of inhibition in potential new antiviral therapeutic pathways for SARS-CoV-2.

20 Jan 2022

New topical cream could help prevent frostbite injuries

Skiers, hikers, soldiers and others exposed to extreme cold temperatures can experience frostbite -; a painful injury that occurs when ice crystals form in the skin. Many extremely cold areas are also remote, and delays in frostbite treatment can result in severe wounds, scarring and even limb amputation

19 Jan 2022

Impact of COVID-19 on male and female reproductive health

A new review article investigated the relation between SARS-CoV-2 infection and reproductive health.

19 Jan 2022

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

A recent review discusses the engineering versatility of polymeric nanoparticles - making a good therapeutic alternative against coronavirus diseases.

19 Jan 2022

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

A new study discusses the activation of the complement system to determine its role in COVID-19-related deaths.

17 Jan 2022

Mutations in SARS-CoV-2 Omicron variant promote cell binding

Researchers in Germany, based on their recent study published in the journal ChemBioChem, have proposed that the elevated occurrence of positively charged amino acids in specific domains of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) Omicron variant spike protein improves viral binding to cellular negatively charged receptors aiding in enhanced infectiousness.

16 Jan 2022

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

In normal cells, electrical voltage patterns provide a blueprint for orderly growth. But with cancer, the opposite happens.

11 Jan 2022

Multiscale model reveals the importance of lipids to the signaling dynamics of RAS proteins

Lawrence Livermore National Laboratory researchers and a multi-institutional team of scientists have developed a highly detailed, machine learning-backed multiscale model revealing the importance of lipids to the signaling dynamics of RAS, a family of proteins whose mutations are linked to numerous cancers.

10 Jan 2022

Researchers study immune cell invasion process in living fruit fly embryos

To fight infections and heal injuries, immune cells need to enter tissue. They also need to invade tumors to fight them from within.

6 Jan 2022

Researchers identify how a critical schistosomiasis drug works on the molecular level

Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.

6 Jan 2022

Host kinase identified as an inhibition target for SARS-CoV-2

In this experiment, the chemical probe SGC-CK2-1 inhibited virus replication at nanomolar concentration, showing a highly selective effect on the kinase.

6 Jan 2022

Humanized antibody shows strong neutralization ability against SARS-CoV-2 Delta variant

Researchers combine SARS-CoV-2 spike vaccination with single-cell B-cell receptor sequencing technology to discover neutralizing antibody candidates.

3 Jan 2022

Cell Membrane News and Research

How SARS-CoV-2 infection progresses throughout the respiratory system

Researchers discover a new function of anti-HIV-1 antibodies

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

New topical cream could help prevent frostbite injuries

Impact of COVID-19 on male and female reproductive health

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

Mutations in SARS-CoV-2 Omicron variant promote cell binding

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

Multiscale model reveals the importance of lipids to the signaling dynamics of RAS proteins

Researchers study immune cell invasion process in living fruit fly embryos

Researchers identify how a critical schistosomiasis drug works on the molecular level

Host kinase identified as an inhibition target for SARS-CoV-2

Humanized antibody shows strong neutralization ability against SARS-CoV-2 Delta variant

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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